Matthew White, MD

Professor of Radiology and Neuroradiology Division Chief

MRI Fellowship Director

Education

• MD: The University of Iowa, Iowa City, Iowa
• Residency: Radiology, Indiana University Medical Center, Indianapolis, IN
• Fellowship: Neuroradiology Fellow, Indiana University Medical Center, Indianapolis, IN

Certifications:

• American Board of Radiology Diagnostic Radiology
• American Board of Radiology Certificate of Added Qualification in Neuroradiology

Achievement:

ASNR 2010 meeting Summa Cum Laude Award for scientific exhibit:  Compact white matter pathways: correlation of T2-weighted imaging with diffusion-tensor imaging tractography.  Matthew L. White, MD, Yan Zhang, MD, Jason T. Helvey, MD, David M. Penn, MD, David P. Poage, MD, Matthew F. Omojola, MD

Research Interest:

Evaluating Survival in Subjects with Primary Intra-axial Brain Tumors by MRI Dynamic Susceptibility Weighted Brain Perfusion Imaging

Funding: Bracco Imaging SpA
Principal Investigator –Matthew L. White, MD. 

The goal of the study is to evaluate subjects with primary intra-axial brain tumors to see how MRI brain tumor perfusion predicts overall survival and progression free survival.  The MRI brain tumor perfusion methodology is contrast based (Multihance) utilizing echo-planar techniques.  Multihance, given its underlying molecular attachment to gadolinium and weak affinity to serum albumin, has been shown to be superlative for echo-planar MRI perfusion analysis.  Given the excellent characteristics of Multihance it was utilized for our MRI brain tumor perfusion exams.

Hypothesis:  We hypothesize that MRI brain tumor perfusion will provide information that is predictive of overall and progression free survival times in subjects with primary intra-axial brain tumors.

Publications:

1. White ML, Zhang Y. Primary angiitis of the central nervous system:  apparent diffusion coefficient lesion analysis.  Clinical Imaging 34(1): 1-6, January 2010
2. White ML, Zhang Y. Three-tesla diffusion tensor imaging of Meyer's loop by tractography, color-coded fractional anisotropy maps, and eigenvectors. Clinical Imaging 34(6): 413-7, Nov-Dec 2010.
3. White ML, Zhang Y, Healey K.  Cervical Spinal Cord Multiple Sclerosis: Evaluation with 2D Multi-Echo Recombined Gradient Echo Magnetic Resonance Imaging.  The Journal of Spinal Cord Medicine 34(1): 93-98, January 2011.
4. White ML, Zhang Y, Yu F, Kazmi S.  Diffusion-Tensor MR Imaging of Cerebral Gliomas:  Evaluating Fractional Anisotropy Characteristics.  AJNR Am J Neuroradiol 32(2): 374-81, February 2011.
5. Wilson TW, Franzen JD, White ML, Knott NL, Wetzel MW.  Broadband Neurophysiological Abnormalities in the Medial Prefrontal Region of the Default-Mode Network in Adults with ADHD.  Accepted Human Brain Mapping.  Published online Nov 18, 2011.
6. Bravo E, White ML, Olney AH, Mcallister JL, Zhang Y. Novel proximal 14q deletion: Clinical and DTI tractography findings in a patient with lissencephaly, agenesis of the corpus callosum and septooptic dysplasia.  Published online Dec 22, 2011 AJNR Am J Neuroradiol.  Accepted for publication.
7. Wilson TW, Wetzel MW, White ML, Knott NL.  Stimulant Medications Normalize Gamma-Frequency Neuronal Activity in Adults with Attention-Deficit/Hyperactivity Disorder.  Accepted The Journal of Psychopharmacology.  Published online Jan 4, 2012.