B. Timothy Baxter, MD, FACS

Tim Baxter

Professor, Department of Surgery
Division of General Surgery - Vascular Surgery
University of Nebraska Medical Center
Surgery Research
985182 Nebraska Medical Center
Omaha, NE 68198-5182, USA
Phone: 402-559-7300
Fax: 402-559-8985

 Curriculum Vitae
Graduate:

University of Colorado Health Sciences Center, Denver, CO
Residency: University of Colorado, Fort Collins, CO
Fellowship: Northwestern University, Chicago, IL
Board Certification:

American Board of Surgery
American Board Surgery Vascular Surgery
Academic Appointment:

Professor of Surgery
 Sub-Specialty

Vascular Surgery
Research Interests: Research Interests Web Link

Publications:

  • Shimizu-Hirota R, Xiong W, Baxter BT, Kunkle SL, Maillard I, Chen XW, Sabeh F, Liu R, Li XY, Weiss SJ. MT1-MMP regulates the PI3KO(middle dot)MI-2/NuRD-dependent control of macrophage immune function. Genes Dev, 26(4):395-413, Feb 2012. Abstract
  • Xiong, W, MacTaggart JN, Knispel R, Worth J, Peridsky Y, Baxter BT.  Blocking TNF-alpha attenuates aneurysm formation in a murine model.  J Immunol, 183(4):2741-6, Aug 2009. Abstract
  • Xiong W, Mactaggart J, Knispel R, Worth J, Zhu Z, Li Y, Sun Y, Baxter BT, Johanning JM:  Inhibition of reactive oxygen species attenuates aneurysm formation in a murine model.  Atherosclerosis, 202(1):128-134, Jan 2009. Abstract
  • Xiong W, MacTaggart J, Knispel R, Persidsky Y, Baxter BT. Key Role of Tumor Necrosis Factor-a in the Development of Abdominal Aortic Aneurysm. J Immunol. 2009 Aug 15;183(4):2741-6. Epub 2009 Jul 20.
  • Xiong W, Knispel R, MacTaggart J, GreinerT C, Weiss SJ, Baxter BT. Mt1-MMP regulates macrophage-dependent elastolytic activity and aneurysm formation in vivo.Journal of Biological Chemistry 2009 Jan 16;284(3):1765-1771. Abstract
  • Rentschler ME, Baxter BT. Screening aortic drug treatments through arterial compliance measurements. Curr Vasc Pharmacol, 6(4):250-7, Oct 2008. Abstract
  • Pipinos II, Swanson SA, Zhu Z, Nella AA, Weiss DJ, Gutti TL, McComb RD, Baxter BT, Lynch TG, Casale GP. Chronically ischemic mouse skeletal muscle exhibits myopathy in association with mitochondrial dysfunction and oxidative damage. Am J Physiol Regul Integr Comp Physiol, 295(1):R290-6, Jul 2008. Abstract
  • Mahoney CR, Hartman CW, Simon PJ, Baxter BT, Neff JR.  Vascular management in rotationplasty. Clin Orthop Relat Res, 466(5):1210-6, May 2008. Abstract
  • Baxter BT, Terrin MC, Dalman RL. Medical management of small abdominal aortic aneurysms.  Circulation, 117(14):1883-9. Review, Apr 2008. Abstract
  • Xiong w, Knispel R, Rameriz F, Dietz H, Baxter BT.  Doxcycline preserves elastin and delays aortic rupture in a mouse model of Marfan syndrome.  J Vasc Surg, 47(1):166-72, Jan 2008. Abstract
  • Rentschler ME, Baxter BT. Medical therapy approach for treating abdominal aortic aneurysm.  Vascular, 15(6):361-5, 2007. Abstract
  • Sun J, Sukhova GK, Yang M, Wolters PJ, MacFarlane LA, Libby P, Sun C, Zhang Y, Liu J, Ennis TL, Knispel R, Xiong W, Thompson RW, Baxter BT, Shi GP. Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest, 117(11):3359-68. Nov 2007. Abstract
  • MacTaggart JN, Xiong W, Knispel R, Baxter BT. Deletion ofCCR2 but notCCR5 or CXCR3 inhibits aortic aneurysm formation. Surgery, 142(2):284-8, Aug 2007. Abstract
  • Baxter BT, Mahoney C, Johnson PJ, Selmer KM, Pipinos II, Rose J, Neff JR. Concomitant arterial and venous reconstruction with resetion of lower extremity sarcomas. Ann Vasc Surg 21(3):272-9, 2007. Abstract
  • Rentschler M, Baxter, BT.  Pharmacological Approaches to Prevent AAA Enlargement and Rupture. New York Academy of Science, 1085:39-46, Nov 2006. Abstract
  • Xiong W, Knispel R, Mactaggart J, Baxter BT.  Effects of tissue inhibitor of metalloproteinase 2 deficiency on aneurysm formation. J Vasc Surg, 44(5):1061-6, Nov 2006. Abstract
  • Baxter BT, Pipinos I. Commentary. Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation. Perspect Vasc Surg Endovasc Ther, 18(3):273-4, Sep 2006. Abstract
  • Pipinos II, Judge AR, Zhu Z, Selsby JT, Swanson SA, Johanning JM, Baxter BT, Lynch TG, Dodd SL. Mitochondrial defects and oxidative damage in skeletal muscle patients with peripheral arterial disease.  Free Radic Biol Med, 15;41(2):262-9, Jul 2006. Abstract
  • Fiotti N, Altamura N, Fisicaro M, Carraro N, Uxa L, Grassi G, Torelli L, Gobbato R, Guarnieri G, Baxter BT, Giansante C.  MMP-9 microsatellite polymorphism and susceptibility to carotid arteries atherosclerosis.  Arterioscler Thromb Vasc Biol, 26(6):1330-6, Jun 2006. Abstract
  • Baxter BT.  Abdominal aortic aneurysm regression by medical treatment: possibility or pipe dream? J Vasc Surg, 43(5):1068-9, May 2006. Abstract
  • Bartoli MA, Parodi FE, Chu J, Pagano MB, Mao D, Baxter BT, Buckley C, Ennis TL, Thompson RW.  Localized administration of doxycycline suppresses aortic dilatation in an experimental mouse model of abdominal aortic aneurysm Ann Vasc Surg, 20(2):228-36, Mar 2006. Abstract
  • Baxter BT, guest editor.  Treatment of peripheral, mesenteric and renal artery aneurysms: contemporary treatment in the endovascular age. Seminar in Vascular Surgery, 18(4), 2005. Abstract
  • Fiotta N, Altamura N, Fisicaro M, Carraro N, Adovasio R, SArra VM, Uxa L, Guarnieri G, Baxter BT, Giansante C. MMP-9 microsatellite polymorphism: association with the progression of intima-media thickening and constrictive remodeling of carotid atherosclerotic plaques.  Atherosclerosis, 182(2):287-92, Oct 2005. Abstract
  • Baxter BT. Heritable diseases of the blood vessels.  Cardiovascular Pathol, 14(4):185-8, Jul-Aug 2005. Abstract
  • Longo GM, Buda SJ, Fiotti N, Xiong W, Grenier TC, Shapiro SD, Baxter BT: MMP-12 has a role in abdominal aortic aneurysms in mice. Surgery. 137(4):457-62, Apr 2005. Abstract
  • Baxter BT. Could medical intervention work for aortic aneurysms? Am J Surg, 188(6):628-32, Dec 2004. Abstract
  • Basalyga DM, Simionescu DT, Xiong W, Baxter BT, Starcher BC, Vyavahare NR. Elastin Degradation and Calcification in an Abdominal Aorta Injury Model. Role of Matrix Metalloproteinase’s. Circulation, 110(22):3480, Nov 2004. Abstract
  • Baxter BT. Presidential address: Commitment-looking for someone willing to go to the trouble. Journal of Vascular Surgery, 39(5):925-30, May 2004. Abstract
  • Xiong W, Zhao Y, Prall A, Greiner TC, Baxter BT. Key roles of CD4+ T cells and IFN-gamma in the development of abdominal aortic aneurysms in a murine model. J Immunol. 2004 Feb 15;172(4):2607-12. Abstract
  • Zhao Y, Xiong W, Yang T, Prall A, Baxter BT, Langnas AN. Xenogeneic skin graft rejection in M-CSF/macrophage deficient osteopetrotic mice. Xenotransplantation, 10(3):232-9, May 2003. Abstract
  • Thompson JS, Baxter BT, Allison JG, Johnson FE, Lee KK, Park WY. Temporal patterns of postoperative complications. Arch Surg, 138(6):596-602, Jun 2003. Abstract
  • Johanning J, Pipinos I, Baxter BT, Lynch TJ.  NO in AAA patients. Surgical Forum 2003.
  • Liu J, Xiong W, Baca-Regen L, Nagase H, Baxter BT. Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells. J. Vasc Surg, 38(6):1376-83, Dec 2003. Abstract
  • Johanning J, Brunz J, Pipinos I, Park J, Leone A, Baxter BT, Lynch T. Altered nitric oxide metabolites in patients with abdominal aortic aneurysm: potential for screening. Journal of the American College of Surgeons, 197(3) S103, 2003.
  •  Longo GM, Xiong W, Greiner T, Baxter BT. MMP2 and MMP-9 work in concert to produce AAA. J Clin Invest. 110(5):625-32, 2002. Abstract