Iraklis Pipinos, MD, FACS

Iraklis Pipinos, MD

Professor, Department of Surgery
University of Nebraska Medical Center
Division of General Surgery
985182 Nebraska Medical Center
Omaha, NE 68198-5182, USA
Phone: 402-559-7300
Fax: 402-559-8985
ipipinos@unmc.edu

Curriculum Vitae

Graduate:

University of Crete, School of Medicine, Crete, Greece, MD
Residency:

Henry Ford Hospital, Dept. of Surgery, Detroit, Michigan
Fellowship: Vascular Surgery: Henry Ford Hospital, Division of Vascular Surgery
Endovascular Surgery: Stanford University, Division of Vascular Surgery, Stanford, CA
Board Certification:

American Board of Surgery
American Board of Vascular Surgery
Academic Appointment:

Professor of Surgery
Sub-Specialty

Vascular Surgery
Endovascular Surgery
Complex Aortic Surgery
Research Interests: Open versus endovascular repair for abdominal aortic aneurysms, Mitochondrial dysfunction in chronically ischemic skeletal muscle, Carotid stenting, Walking impaiment in claudication.

Publications:

  • Wurdeman SR, Myers SA, Johanning JM, Pipinos II, Stergiou N. External work is deficient in both limbs of patients with unilateral PAD. Med Eng Phys. 2012 Feb 7. [Epub ahead of print] Abstract
  • Gupta PK, Mactaggart JN, Natarajan B, Lynch TG, Arya S, Gupta H, Fang X, Pipinos II. Predictive factors for mortality after open repair of paravisceral abdominal aortic aneurysm. J Vasc Surg. 2011 Dec 29. [Epub ahead of print] Abstract
  • Kamenskiy AV, Dzenis YA, Mactaggart JN, Lynch TG, Jaffar Kazmi SA, Pipinos II. Nonlinear Mechanical Behavior of The Human Common, External, and Internal Carotid Arteries In Vivo.J Surg Res. 2011 Oct 24. [Epub ahead of print] Abstract
  • Tu H, Liu J, Zhu Z, Zhang LB, Pipinos II, Li YL. Mitochondria-derived superoxide and voltage-gated sodium channels in baroreceptor neurons from chronic heart failure rats. J Neurophysiology. 2011 Nov 9. [Epub ahead of print] Abstract
  • Gupta PK, Gupta H, Sundaram A, Kaushik M, Fang X, Miller WJ, Esterbrooks DJ, Hunter CB, Pipinos II, Johanning JM, Lynch TG, Forse RA, Mohiuddin SM, Mooss AN. Development and validation of a risk calculator for prediction of cardiac risk after surgery. Circulation. 2011 Jul 26;124(4):381-7. Epub 2011 Jul 5. Abstract
  • Arya S, Pipinos II, Garg N, Johanning J, Lynch TG, Longo GM. Carotid Endarterectomy is Superior to Carotid Angioplasty and Stenting for Perioperative and Long-Term Results. Vasc Endovascular Surg. 2011 Aug;45(6):490-8. Epub 2011 Jun 5. Abstract
  • Kamenskiy AV, Dzenis YA, Mactaggart JN, Desyatova AS, Pipinos II. In vivo three-dimensional blood velocity profile shapes in the human common, internal, and external carotid arteries. J Vasc Surg. 2011 Oct;54(4):1011-20. Epub 2011 May 28. Abstract
  • Pankajakshan D, Makinde TO, Gaurav R, Del Core M, Hatzoudis G, Pipinos I, Agrawal DK. Successful Transfection of Genes Using AAV-2/9 Vector in Swine Coronary and Peripheral Arteries. J Surg Res. 2011 Mar 21. [Epub ahead of print] Abstract
  • Myers SA, Pipinos II, Johanning JM, Stergiou N. Gait variability of patients with intermittent claudication is similar before and after the onset of claudication pain. Clin Biomech (Bristol, Avon). 2011 Aug;26(7):729-34. Epub 2011 Mar 29. Abstract
  • Pankajakshan D, Jia G, Pipinos I, Tyndall SH, Agrawal DK. Neuropeptide Y receptors in carotid plaques of symptomatic and asymptomatic patients: Effect of inflammatory cytokines. Exp Mol Pathol. 2011 Feb 23;90(3):280-286. Abstract
  • Gupta PK, Pipinos II, Miller WJ, Gupta H, Shetty S, Johanning JM, Longo GM, Lynch TG. A Population-Based Study of Risk Factors for Stroke after Carotid Endarterectomy Using the ACS NSQIP Database. J Surg Res. 2011 May 15; 167(2):182-91. Epub 2010 Nov 11. Abstract
  • Tran TP, Tu H, Pipinos II, Muelleman RL, Albadawi H, Li YL. Tourniquet-induced acute ischemia-reperfusion injury in mouse skeletal muscles: Involvement of superoxide. Eur J Pharmacol. 2011 Jan 10;650(1):328-34. Epub 2010 Oct 29. Abstract
  • Huisinga JM, Pipinos II, Stergiou N, Johanning JM. Treatment with pharmacological agents in peripheral arterial disease patients does not result in biomechanical gait changes. J Appl Biomech. 2010 Aug;26(3):341-8. Abstract
  • Myers SA, Stergiou N, Pipinos II, Johanning JM. Gait variability patterns are altered in healthy young individuals during the acute reperfusion phase of ischemia-reperfusion. J Surg Res. 2010 Nov;164(1):6-12. Epub 2010 May 18. Abstract
  • Longo GL, Pipinos II. Endovascular techniques for arch vessel reconstruction, Accepted J Vasc Surg June 2010. Abstract
  • Koutakis P, Johanning JM, Myers SA, Stergiou N, Longo GM, Pipinos II. Abnormal joint powers before and after the onset of claudication symptoms, Accepted J Vasc Surg March 2010 Abstract
  • Huisinga JM, Pipinos II, Johanning JM, Stergiou N. The effect of pharmacological treatment on gait biomechanics in peripheral arterial disease patients. J Neuroeng Rehabil. 2010 Jun 7;7(1):25. Abstract
  • Pisimisis GT, Kantor B, Kalra M, Pipinos II. Thrombus of the internal carotid artery: the contribution of computed tomographic angiography to clinical management. Vasc Endovascular Surg. 2010 May;44(4):302-4. Abstract
  • Lederle FA, Freischlag JA, Kyriakides TC, Padberg FT Jr, Matsumura JS, Kohler TR, Lin PH, Jean-Claude JM, Cikrit DF, Swanson KM, Peduzzi PN; Open Versus Endovascular Repair (OVER) Veterans Affairs Cooperative Study Group. Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial. JAMA. 2009 Oct 14;302(14):1535-42.
  • Koutakis P, Pipinos II, Myers SA, Stergiou N, Lynch TG, Johanning JM. Joint torques and powers are reduced during ambulation for both limbs in patients with unilateral claudication. J Vasc Surg. 2010 Jan;51(1):80-8. Abstract
  • Kasotakis G, Pipinos II, Lynch TG. Aspirin resistance: Current evidence and clinical implications. J Vasc Surg. 2009 Dec;50(6):1500-10. Abstract
  • Kamenskiy AV, Pipinos II, Desyatova AS, Salkovskiy YE, Kossovich LY, Kirillova IV, Polyaev VO, Bockeria LA, Morozov KM, Lynch TG, Dzenis YA. Finite Element Model of the Patched Human Carotid. Vasc Endovascular Surg. 2009 Dec;43(6):533-41 Abstract
  • Pipinos II, Myers SA, Johanning JM, Stergiou N. Author reply to the letter: Regarding "Gait variability is altered in patients with peripheral arterial disease" by Crowther RG, Spinks WL, Leicht AS, Golledge J. J Vasc Surg. 2009 Oct;50(4):976-7.
  • Garg N, Karagiorgos N, Pisimisis GT, Sohal DP, Longo GM, Johanning JM, Lynch TG, Pipinos II. Cerebral protection devices reduce periprocedural strokes during carotid angioplasty and stenting: a systematic review of the current literature. J Endovasc Ther. 2009 Aug;16(4):412-27. Abstract
  • Gordon JR, Wahls T, Carlos RC, Pipinos II, Rosenthal GE, Cram P. Failure to recognize newly identified aortic dilations in a health care system with an advanced electronic medical record. Ann Intern Med. 2009 Jul 7;151(1):21-7, W5. Abstract
  • Myers SA, Johanning JM, Stergiou N, Celis RI, Robinson L, Pipinos II. Gait variability is altered in patients with peripheral arterial disease. J Vasc Surg. 2009 Apr;49(4):924-931. Abstract
  • Pipinos II, Pisimisis GT, Burjonrappa SC, Johanning JM, Longo GM, and Lynch TG. One Patent Intracranial Collateral Predicts Tolerance of Flow Reversal during Carotid Angioplasty and Stenting. Ann Vasc Surg. 2009 Jan-Feb;23(1):32-8. Abstract
  • Celis R, Pipinos II, Scott-Pandorf MM, Myers SA, Stergiou N, Johanning JM. Peripheral arterial disease affects kinematics during walking. J Vasc Surg. 2009 Jan;49(1):127-32. Abstract
  • Weiss DJ, Pipinos II, Longo GM, Lynch TG, Rutar FJ, Johanning JM. Direct and indirect measurement of patient radiation exposure during endovascular aortic aneurysm repair. Ann Vasc Surg. 2008 Nov;22(6):723-9. Abstract
  • Chen SJ, Pipinos II, Johanning JM, Radovic M, Huisinga JM, Myers SA, Stergiou N. Bilateral intermittent claudication results in alterations in the gait biomechanics at the hip and ankle joints during gait. J Biomech. 2008;41(11):2506-14. Abstract
  • Pipinos II, Swanson SA, Zhu Z, Nella AA, Weiss DJ, Gutti TL, McComb RD, Baxter BT, Lynch TG, and Casale GP. Chronically ischemic mouse skeletal muscle exhibits myopathy in association with mitochondrial dysfunction and oxidative damage. Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R290-6. Abstract
  • Pipinos II, Judge AR, Selsby JT, Zhu Z, Swanson SA, Nella AA, Dodd SL. The myopathy of peripheral arterial occlusive disease: Part 2. Oxidative Stress, Neuropathy, and Shift in Muscle Fiber Type. Vasc Endovascular Surg. 2008 Apr-May;42(2):101-12. Abstract
  • Pipinos II, Judge AR, Selsby JT, Zhen Zhu, Swanson SA, Nella AA, Dodd SL. The Myopathy of Peripheral Arterial Occlusive Disease: Part 1. Functional and Histomorphological Changes and Evidence for Mitochondrial Dysfunction. Vasc Endovascular Surg. 2008 Jan;41(6):481-489. Abstract
  • Myers SA, Johanning JM, Stergiou N, Lynch TG, Longo GM, Pipinos II. Claudication Distances and the Walking Impairment Questionnaire best describe the Ambulatory Limitations in Patients with Symptomatic Peripheral Arterial Disease. J Vasc Surg. 2008 Mar;47(3):550-555. Abstract
  • Makris KI, Nella AA, Zhu Z, Swanson SA, Casale GP, Yannam T, Judge AR, Pipinos II. The mitochondriopathy of Peripheral Arterial Disease. Vascular. 2007; 15(6): 336–343. Abstract
  • Scott-Pandorf MM, Stergiou N, Johanning JM, Robinson L, Lynch TG, Pipinos II. Peripheral Arterial Disease Affects Ground Reaction Forces during Walking. J Vasc Surg. 2007 Sep;46(3):491-9. Abstract
  • Trigilio-Black CM, Ringley CD, McBride CL, Sorensen VJ, Thompson JS, Longo GM, Pipinos II, Johanning JM. Inferior vena cava filter placement for pulmonary embolism risk reduction in super morbidly obese undergoing bariatric surgery. Surg Obes Relat Dis. 2007 Jul-Aug;3(4):461-4. Abstract
  • Lynch TG, Pipinos II. Editorial regarding “Aspirin resistance among long-term aspirin users after carotid endarterectomy and controls: Flow cytometric measurement of aspirin-induced platelet inhibition” J Vasc Surg. 2007 Jun;45(6):1147
  • Baxter BT, Mahoney C, Johnson PJ, Selmer KM, Pipinos II, Rose J, Neff JR. Concomitant arterial and venous reconstruction with resection of lower extremity sarcomas. Ann Vasc Surg. 2007 May-Jun;21(3):272-9. Abstract
  • Garg N, Pipinos II, Longo GM, Thorell WE, Lynch TG, Johanning JM. Detachable coils for repair of extraparenchymal renal artery aneurysms: an alternative to surgical therapy. Ann Vasc Surg. 2007 Jan;21(1):97-110. Abstract
  • Baxter BT, Pipinos I. Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation. Perspect Vasc Surg Endovasc Ther. 2006 Sep;18(3):273-4 Abstract
  • Pipinos II, Bruzoni M, Johanning JM, Longo GM, Lynch TG. Transcervical carotid stenting with flow reversal for neuroprotection: technique, results, advantages, and limitations. Vascular. 2006 Sep-Oct;14(5):245-55. Abstract
  • Pipinos II, Judge AR, Zhu Z, Selsby JT, Swanson SA, Johanning JM, Baxter BT, Lynch TG, Dodd SL. Mitochondrial defects and oxidative damage in patients with peripheral arterial disease. Free Radic Biol Med. 2006 Jul 15;41(2):262-9. Abstract
  • Pipinos II, Hopp R, Edwards WD, Radio SJ. Giant-cell temporal arteritis in a 17-year-old male. J Vasc Surg. 2006 May;43(5):1053-5. Abstract
  • Pipinos II. Book review on “Assessing and Modifying the Vulnerable Atherosclerotic Plaque, Editor: Valentin Fuster, M.D. with Assistance from William Insull, Jr., M.D., Blackwell Publishers; 1st edition (June 15, 2002). Vascular and Endovascular Surgery, May/June 2006;. 40(3): 255
  • MacTaggart JN, Pipinos II, Johanning JM, Lynch TG. Acrylic cement pulmonary embolus masquerading as an embolized central venous catheter fragment. J Vasc Surg. 2006 Jan; 43(1):180-3. Abstract
  • Sandhu RS, Pipinos II. Isolated iliac artery aneurysms. Semin Vasc Surg. 2005 Dec;18(4):209-15. Abstract
  • Pipinos II, Johanning JM, Pham CN, Soundararajan K, Lynch TG. Transcervical approach with protective flow reversal for carotid angioplasty and stenting. J Endovasc Ther. 2005 Jul-Aug;12(4):446-53. Abstract
  • Ganti AK, Pipinos I, Culcea E, Armitage JO, Tarantolo S. Successful hematopoietic stem-cell transplantation in multicentric Castleman disease complicated by POEMS syndrome. Am J Hematol. 2005 Jun 24;79(3):206-210 Abstract
  • Pipinos II, Sharov VG, Shepard AD, Anagnostopoulos PV, Katsamouris A, Todor A, Filis KA, Sabbah HN. Abnormal mitochondrial respiration in skeletal muscle in patients with peripheral arterial disease. J Vasc Surg. 2003 Oct;38(4):827-32. Abstract
  • Guerrero A, Gibson K, Kralovich KA, Pipinos I, Agnostopoulos P, Carter Y, Bulger E, Meissner M, Karmy-Jones R. Limb loss following lower extremity arterial trauma: what can be done proactively? Injury. 2002 Nov;33(9):765-9. Abstract
  • Lynch TG, Pipinos II, Boska MD. Editorial regarding "Can carotid endarterectomy improve metabolic status in patients with asymptomatic internal carotid artery flow lesion? Studies with localized in vivo proton magnetic resonance spectroscopy". J Vasc Surg. 2002 Sep;36(3):646-8 Abstract
  • Filis K, Arko FR, Johnson BL, Pipinos II, Harris EJ, Olcott C, Harris EJ, Zarins CK. Duplex ultrasound criteria for defining the severity of carotid stenosis. Ann Vasc Surg. 2002 Jul;16(4):413-21 Abstract
  • Pipinos II, Boska MD, Shepard, AD, Anagnostopoulos, PV, and Katsamouris A. Pentoxifylline Reverses Oxidative Mitochondrial Defect in Claudicating Skeletal Muscle. J Surg Res 2002,102: 126–132 Abstract