The University of Nebraska
Center for Environmental Health and Toxicology
Promoting the integration of new perspectives
and insights into education and research
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The University of Nebraska |
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The Center for Environmental Toxicology offers graduate training leading to the M.S. or Ph.D. degree in various multidisciplinary aspects of environmental toxicology. Research opportunities in the program include mechanisms of carcinogenesis, mechanisms of alcohol toxicity and metal toxicity, mechanisms of DNA damage, human molecular genetics, environment-gene interactions, bioinformatics, immunotoxicology, ecological toxicology, agrochemicals in soil and water, food toxins, ultratrace determination of biological compounds, and synthetic and mechanistic bio-organic chemistry. Students may conduct their studies on the UNMC, UNL or UNO campus.
Required Courses
All students (M.S. and Ph.D.) are required to complete successfully two semesters of biochemistry, a semester of statistics and two semesters of toxicology. Biochemistry I and II are available at UNMC (BRTP 821/822) and UNL (BioChm 831/832). Students may take Biostatistics I at UNMC (PSM 806) or statistical Methods in Research at UNL (Biometry 801). Basic Toxicology (TOX 888) and Advanced Toxicology (TOX 950) will be provided to students at both campuses. All students must participate in the Center seminar series.
Track 1: [Research (Ph.D.) track] requires a minimum of 30 credit hours, 20-24 hours of course work and 6-10 hours of thesis; half of the total credit hours, including thesis, must be in the major.
Track 2: [Non-research (non-Ph.D.) track] requires a minimum of 36 credit hours, with: for UNL, a minimum of 18 hours in the major or two minors of 9 hours with 15 hours in the major; no thesis is required; at least 12 credit hours must be in upper level (800/900) level courses.
In addition to the required courses, at least two elective 800/900 level courses must be taken. A dissertation with an oral defense must be presented. During the second or third year, a grant proposal must be prepared on a subject related to toxicology, yet outside the immediate area of dissertation research; the proposal must conform to the guidelines of an appropriate federal agency (NIH, NSF, USDA, DoD, etc.); after review by the Supervisory Committee and other selected reviewers, the student must defend the grant proposal in an oral examination covering the proposal and related subject material. All students are required to submit at least one scientific article for publication. Students must participate in the Center seminar program, attending a minimum of 12 seminars.
Course DescriptionsTOX 875 CHEMICAL CARCINOGENESIS, 2 cr II even yrs. This course will present the basic concepts of chemical carcinogenesis, and introduce the major carcinogens, their biochemistry of activation and mode of action. Lect. 2. Prereq: Biochemistry or permission of instructor.
TOX 888 PRINCIPLES OF TOXICOLOGY, 3 cr, odd yrs. An introduction to the principles of toxicology, mechanisms of toxicity, measures used in the treatment of poisoning and specific information pertaining to the categories of toxic agents responsible for the majority of toxicological emergencies.
TOX 896 RESEARCH OTHER THAN THESIS, 1-9 cr.
TOX 899 MASTER’S THESIS, cr. arr.
TOX 902 SPECIAL TOPICS, 1-4 cr. - max 8
TOX 950 ADVANCED TOXICOLOGY, 3 cr II odd yrs. This course deals with the adverse effects of chemicals on biological systems. Physiological and biochemical mechanisms of toxicity at the cellular and subcellular levels will be emphasized. Prereq: Permission of instructor and PHSC 888 or equivalent.
TOX 970 SEMINAR, 1 cr.
TOX 999 DOCTORAL DISSERTATION, cr. arr.
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Center for Environmental Health and Toxicology
986805 Nebraska Medical Center
Omaha, Nebraska 68198-6805
Phone: (402) 559-8924
Facsimile: (402) 559-8068
E-mail: uncetox@unmc.edu