The Eppley Institute for Research in Cancer (unmc.edu/eppley/) at the University of Nebraska Medical Center (UNMC) seeks candidates for full-time senior faculty positions at the rank of Associate Professor or Professor. Candidates are expected to have an active, extramurally-funded research program in basic/translational cancer research that is complementary to existing strengths and aligned with the overall directions of the Institute and Fred & Pamela Buffett Cancer Center, an NCI-designated Cancer Center. Institute faculty members are expected to play important roles in the research programs in the Buffett Cancer Center, participate in graduate-level teaching in the Cancer Research Doctoral Program and/or other UNMC graduate programs and engage in institutional service based on their expertise.
Rank and compensation depend upon qualifications. EEO/AA individuals from diverse backgrounds are encouraged to apply. To apply, go to https://jobs.unmc.edu and reference requisition #2020-050. Please contact Chris Whitted (Email) with questions.
The Eppley Institute has 25 tenured or tenure-leading faculty members. For more information about the Institute see: https://www.unmc.edu/eppley/ The Institute is a mainstay of the NCI-designated Fred & Pamela Buffett Cancer Center (FPBCC). The Institute Director, Dr. Cowan, is also Director of the FPBCC.
The successful candidate is expected to:
1. Develop an independent, extramurally-funded research program in basic/translational cancer research that is complementary to existing strengths and aligned with the overall directions of the NCI-designated Fred & Pamela Buffett Cancer Center (FPBCC).
2. Participate in graduate-level teaching in the Cancer Research Doctoral Program and/or other UNMC graduate programs, and engage in institutional service based on their expertise.
3. Function as an active and collaborative participant in the FPBCC.
Fred & Pamela Buffett Cancer Center
The Fred & Pamela Buffett Cancer Center is in a dynamic growth phase and committed to expansion of all its research programs. A state-of-the-art $335 million complex for the Fred & Pamela Cancer Center, including a 260,000 sq. ft. cancer research tower, a multidisciplinary outpatient clinic (surgical, medical, and radiation oncology), and a 108 bed inpatient cancer hospital opened in 2017.
The FPBCC has over 100 primary members focused on externally funded research and organized into three main programs:
Molecular Biology and Etiology (MBEP)
The overall goal of the Molecular and Biochemical Etiology Program (MBEP) is to discover and validate novel mechanisms of cancer initiation and progression that could lead to new biomarkers and therapeutic targets, with an emphasis on breast, prostate, and ovarian cancers. The members of this program focus on the discovery of alterations in molecular mechanisms that maintain genome stability, intracellular signaling mechanisms, and tumor cell- microenvironment interactions, as well as the development and application of in vitro cell-based and whole animal-based models to validate cancer mechanisms, biomarkers, and targets.
Cancer Genes and Molecular Regulation (CGMRP)
The overall goal of the CGMRP is to develop strategies for the identification and validation of cellular targets for cancer therapy, and for the discovery of small molecules and delivery methods that affect target function. The CGMRP has 28 members from nine departments with multidisciplinary interests in cancer target discovery and development. Nine new members have been recruited to the CGMRP over the previous period of funding. The program membership has technical strengths in super resolution microscopy, high throughput RNA interference, small molecule screening and delivery, synthetic and medicinal chemistry, and the development of evaluative preclinical models. The research interests of the program faculty are organized around three themes: cancer target identification, cancer target validation, and drug development/translational research.
Gastrointestinal Cancer (GICP)
The overall goals of the GICP are to better understand the pathogenesis and pathophysiology of GI cancers, identify and validate new diagnostic and prognostic tools for GI cancer management, and develop new therapeutic options for patients with GI malignancies. To address these goals, the GICP has been organized into three interacting themes, each of which integrates basic and translational science: Mechanisms of GI Tumorigenesis, Biomarkers, and Novel Treatment Approaches. The establishment of the GICP reflects the success of a longstanding Working Group in Pancreatic Cancer at UNMC, the foundation of which includes a SPORE in Pancreatic Cancer and a robust Rapid Autopsy Program for comprehensive collection of tissues from pancreatic cancer patients. Additional support for research initiatives in pancreatic cancer comes from several multi-investigator grants in the area of biomarker discovery and validation and novel treatment approaches.
For more information about the Cancer Center see: http://www.unmc.edu/cancercenter.