CBP Mission: To discover and validate mechanisms of cancer initiation and progression that may lead to novel biomarkers and therapeutic targets, with an emphasis on breast, prostate and ovarian cancers. The following programmatic goals provide a pathway to this end:
1) Discover alterations of molecular mechanisms that maintain intact genomes.
2) Discover alterations in intracellular signaling mechanisms and tumor cell-microenvironment interactions.
3) Validate cancer mechanisms, biomarkers, and targets using cell-based in vitro and animal models.
The CBP is organized into 3 themes that closely align with the goals delineated above.
CBP THEMES |
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Genome Instability and Cancer |
Signaling Mechanisms in Cancer |
Cellular Basis of Cancer |
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Program Co-Leaders:
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Hamid Band, MD, PhD 402.559.8572 |
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