Cancer Biology Program (CRP)

CBP Mission: To discover and validate mechanisms of cancer initiation and progression that may lead to novel biomarkers and therapeutic targets, with an emphasis on breast, prostate and ovarian cancers. The following programmatic goals provide a pathway to this end:

1) Discover alterations of molecular mechanisms that maintain intact genomes.
2) Discover alterations in intracellular signaling mechanisms and tumor cell-microenvironment interactions.
3) Validate cancer mechanisms, biomarkers, and targets using cell-based in vitro and animal models.

The CRP is organized into 3 themes that closely align with the goals delineated above.

 

CRP THEMES

 

Genome Instability and Cancer

 

Signaling Mechanisms in Cancer

 

Cellular Basis of Cancer

Discover alterations of molecular mechanisms that maintain intact genomes

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Discover alterations in intracellular signaling and tumor cell-microenvironment interactions

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Using in vitro and animal models, validate cancer mechanisms, biomarkers and targets

Program Co-Leaders:

Hamid Band, MD, PhD

Hamid Band, MD, PhD
Professor, Eppley Institute
Director of the Center for Breast Cancer Research
Associate Director of Translational Research

402.559.8572 
hband@unmc.edu 

Pankaj Singh, PhD

Pankaj Singh,  PhD 
Professor, Eppley Institute
Co-Leader, Cancer Biology Program

402.559.2726
pankaj.singh@unmc.edu