Targets, Modulators and Delivery Program (TPDP)

TMDP Mission: To develop strategies for the identification and validation of cellular targets for cancer therapy, and for the discovery of small molecules and delivery methods that affect target function.

The TMDP is organized to promote collaboration and catalyze the translation of scientific discoveries from all FPBCC basic research program members, while providing FPBCC members with translational research programs access to potential new targets for therapeutic development and evaluation. The research interests of TMDP faculty are organized around the following three themes:




Signal Transduction


Molecular Target Validation


Drug Delivery/Preclinical Evaluation

Characterization and dissection of pathways affecting cancer; identification of new targets for cancer therapy.

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Analysis of putative targets for cancer therapy; development of preclinical models.

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Analysis and testing of novel methods for drug delivery and models for cancer therapy.

Program Co-Leaders:

Robert Lewis

Robert Lewis, PhD 
Professor, Eppley Institute


Amar Natarajan

Amar Natarajan, PhD
Professor, Eppley Institute


Sarah Holstein

Sarah Holstein, MD
Associate Professor, Internal Medicine
Division of Oncology & Hematology