Targets, Probes and Delivery Program (TPDP)

TPDP Mission: To develop strategies for the identification and validation of cellular targets for cancer therapy, and for the discovery of small molecules and delivery methods that affect target function.

The TPDP is organized to promote collaboration and catalyze the translation of scientific discoveries from all FPBCC basic research program members, while providing FPBCC members with translational research programs access to potential new targets for therapeutic development and evaluation. The research interests of TPDP faculty are organized around the following three themes:

 

TPDP THEMES

 

Signal Transduction

 

Molecular Target Validation

 

Drug Delivery/Preclinical Evaluation

Characterization and dissection of pathways affecting cancer; identification of new targets for cancer therapy.

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Analysis of putative targets for cancer therapy; development of preclinical models.

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Analysis and testing of novel methods for drug delivery and models for cancer therapy.

Program Co-Leaders:

Robert Lewis

Robert Lewis, PhD 
Professor, Eppley Institute

402-559-8290 
rlewis@unmc.edu

Amar Natarajan

Amar Natarajan, PhD
Professor, Eppley Institute

402-559-3793
anatarajan@unmc.edu

Sarah Holstein

Sarah Holstein, MD
Associate Professor, Internal Medicine
Division of Oncology & Hematology

402-559-8500
sarah.holstein@unmc.edu