The SMART IRB Online Reliance System is designed to harmonize and streamline the IRB review process for multisite studies, while also serving as a roadmap for institutions to implement the National Institutes of Health (NIH) Policy on the Use of a Single Institutional Review Board for Multisite Research, which took effect on January 25, 2018.
Joining SMART IRB
- Joining and using SMART IRB is free, and is designed to reduce the time and effort involved in negotiating reliance agreements between institutions and collaborators. The University of Nebraska Medical Center has already been registered with SMART IRB.
Using the Online Reliance System
- This system allows investigators and institutions the capability to manage study-specific reliance agreements throughout all steps of the reliance process. The Overall Principal Investigator (PI) of a multisite study works with the Points of Contact (POCs) for each participating institution involved in the study to determine an appropriate reliance arrangement. Together they will identify a Reviewing IRB and determine which institutions will rely upon that IRB for the review and oversight of the research. Please email the UNMC Pediatric IRB for the current POC and for further assistance in getting started.
SMART IRB Resources
- There are a variety of resources available for all participants in the reliance process, including study teams, reviewing IRBs, relying institutions, and more. Please visit the SMART IRB Resources page for more information, including standard operating procedures, forms, and webinars designed to familiarize users with the Online Reliance System.