Phase 1 Course Descriptions
The course descriptions for the Phase 1 Foundations of Medicine curriculum is below. Click on each heading to view the blocks for that semester.
Semester 1  

M-ID 501 - Fundamentals
5 cr. hrs

This 5-week Block presents an integrated, comprehensive course that covers introductory information needed by all subsequent Blocks within Phase 1 of the curriculum.  Material included in the Fundamentals Block includes content in biochemistry and cell biology, medical genetics, embryology, basic histology, general pathology, and basic pharmacologic principles.  In addition, students are exposed to foundations of population health, clinical skills, and health systems quality. The block will utilize a combination of lectures, laboratories, team-based learning, case-based small groups, standardized patient encounters, patient-oriented problem-solving sessions, and flipped classroom activities as instructional methods.

M-ID 513 - Blood, Defenses and Invaders
6 cr. hrs

Blood, Defenses and Invaders takes an integrative approach to cover the immune system and pathogens that invade the cellular and humeral defenses. Topics include hematopoiesis, cellular interactions, antibody formation, antigen-antibody reactions, cell-mediated immunity, and the biological effects of immunological reactions. In addition, a comprehensive approach evaluating the pathogenesis, epidemiology, physical diagnosis and treatment of bacterial, viral, fungal and parasite-mediated infectious diseases will be covered throughout this 6-week course. Finally, the course will elaborate on the synthesis and function of hemoglobin, red blood cell structural components, blood types including Rh types, the pathogenesis of anemia, leukemia, and a basic understanding of blood banking and transfusion medicine. Students will also investigate various components of the normal coagulation process including vasculature, platelets, pro-coagulants, and natural anticoagulation. 

M-ID 504 – Musculoskeletal and Integument
6 cr. hrs

The student enrolled in the 6-week Integumentary and Musculoskeletal block will learn about the normal structure and function of the integumentary and musculoskeletal systems, and naturally progress to recognize the etiology and manifestations of pathologic conditions of these two systems.  Students will actively apply basic knowledge about the human body through dissection, virtual histology, small group interactions, and dynamic lectures.  This course is designed to prepare the student for real-life patient encounters, subsequent to mastery of surface anatomy and physical examination skills. Basic scientists and clinician educators will work together to bring the requisite baseline fundamental knowledge into the clinical practice of medicine.

Semester 2  

M-ID 505 - Circulatory
5 cr. hrs

This is a 5-week-long, organ system-specific block. The curriculum is designed to help students acquire fundamental knowledge of cardiac and vascular histology, embryology, anatomy, and physiology then apply that knowledge toward building a more comprehensive understanding of various cardiovascular diseases such as hypertension, dyslipidemia, atherosclerosis, ischemic heart disease, vasculitis, cardiomyopathies, heart failure, congenital cardiac disorders, valvular heart disease, pericardial diseases, cardiac dysrhythmias, arterial and venous vascular disorders, traumatic and mechanical disorders of the cardiovascular system, and heart disease caused by infectious agents. In addition, students will be exposed to fundamentals of hospital systems, population health, communication skills, evidence-based medicine, professionalism and resilience as it pertains to the circulatory system. Instruction will be provided in the form of lectures, laboratories, team-based learning, case-based small groups, standardized patient encounters, patient-oriented problem-solving sessions, and flipped classroom activities.

M-ID 506 - Respiratory
4 cr. hrs

The 4-week Respiratory block will be a guided expedition of the anatomy, physiology, biochemistry, pharmacology, genetics, histopathology, and imaging of the respiratory system. Learning modalities will involve interactive lectures, ‘flipped classroom’ activities, small group discussions and case-based explorations of the normal state and the variety of diseases that afflict the respiratory system. Students will obtain knowledge of the structure and function of the entire respiratory system with comparative analysis of respiratory mechanics, gas exchange and oxygen as well as carbon dioxide homeostasis under normal and diseased conditions. They will differentiate important diseases affecting the lung parenchyma, airways, blood vessels, pleura and chest wall, including the impact of sleep-disordered breathing, and select appropriate therapy options for these diseases. Students will identify changes in the nose, throat and respiratory system in gross anatomy, imaging, and histology, in addition to taking a comprehensive history and physical examination, to include consideration of social and environmental factors.

M-ID 507 - Renal
3 cr. hrs

The Renal block is intended to provide a strong foundation in the basic sciences relating to the kidney as well in clinical nephrology.  The initial phase of the 3-week block will focus on providing fundamental knowledge of renal anatomy, histology, physiology, and pharmacology.  Teaching methods for these topics will be via traditional lectures, interactive lectures, and laboratories.  The remainder of the curriculum will focus on clinical nephrology with the following areas to be covered: electrolyte disorders, acid-base disorders, introduction to clinical nephrology, acute renal failure, chronic kidney disease, glomerular diseases, and hypertension.  The Nebraska Medicine Division of Nephrology faculty will deliver this learning content via a mix of both traditional lectures as well as active learning methods.

M-ID 508 - Neurosciences
8 cr. hrs

The 8-week Neurosciences block covers the basic science core concepts of neuroanatomy and neurophysiology that are necessary for a medical practitioner to clinically evaluate a patient with neurological and psychiatric diseases. Building upon this foundation, the pathophysiology of diseases affecting the brain and special senses and the clinical presentation of these diseases are covered. Treatment of these diseases, including pharmacological, is integrated with the clinical focus. The student will learn how to use the physical examination to assess the patient with diseases affecting the nervous system and special senses.  Learning methods used in the block will be lecture, labs, small group, and clinical skill sessions.

Semester 3  

M-ID 510 - Gastrointestinal
6 cr. hrs

In this 6-week block, students apply basic science knowledge to explain the normal and pathological states of the female and male genitourinary and reproductive systems and to relate that knowledge to the diagnosis, treatment, and prevention of disease. This block has as its foundation the anatomy of the pelvic and perineal regions and other structures associated with reproduction as well as the biology and endocrine regulation of reproductive processes such as gametogenesis, fertility, pregnancy, and menopause. These principles will then be applied to clinical understanding of pathologies of the genitourinary and reproductive systems. This block also includes capstone coverage of embryology to review processes of human development, both normal and abnormal. Learning modalities will involve both traditional and interactive lectures and laboratories, small group case-based discussions, patient simulation experiences, and clinician and patient panel sessions.

M-ID 511 -  Endocrine
3 cr. hrs

The goal of this 3-week block is to apply knowledge of endocrine physiology to understand the pathophysiology of the endocrine system and relate this information to the diagnosis and treatment of endocrine diseases. Topics covered include endocrine cells, tissues, structure, function, as well as hormone synthesis, secretion, action, and metabolism. This includes the hypothalamus, pituitary, thyroid, adrenal, parathyroid, metabolic bone disease, the endocrine pancreas, glucose homeostasis, diabetes, and obesity. Students will acquire the knowledge by interactive lectures, team-based learning, case vignettes, and small-group sessions.

M-ID 512 - Genitourinary/Reproductive and Developmental (GURD)
6 cr. hrs

In this 6-week block, the students will apply basic science knowledge to explain the normal and pathological states of the urinary tract and reproductive systems and relate that knowledge to the diagnosis, treatment, and prevention of disease. This block includes capstone coverage of embryology in order to explain processes of human development, both normal and abnormal. Methods of instruction will include small-group sessions, case-based learning, E-modules, online case vignettes, and lectures with an interactive approach.

M-ID 530 - Transitions I
2 cr. hrs

Multi-Organ Systems Block: This two-week block revisits fundamental science content as covered in the preceding organ systems blocks. The goal of this transitional block is to provide a structured review and combine high-yield material from the prior organ systems blocks through the lens of conditions related to multi-organ disease processes as preparation for USMLE Step 1. This block uses a case-based approach to provide students a means to apply previously encountered material in a new clinical context of complex disease processes involving multi-organ systems such as Infectious Disease, Rheumatology, and Immunology. The block utilizes a mixture of small group activities, large class discussions, and is comprised approximately 50% independent study time. Focus is placed on formative assessment garnered through liberal use USMLE-style questions.