{"id":4784,"date":"2024-11-18T14:04:42","date_gmt":"2024-11-18T20:04:42","guid":{"rendered":"https:\/\/www.unmc.edu\/elearning\/egallery\/?p=4784"},"modified":"2026-02-20T14:35:19","modified_gmt":"2026-02-20T20:35:19","slug":"potassium-aldosterone-switch","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/elearning\/egallery\/potassium-aldosterone-switch\/","title":{"rendered":"Low Volume High Potassium Aldosterone Switch"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p>The module begins with an overview of the relevant renal physiology, focusing on the mechanisms of sodium and potassium handling. It then examines how low extracellular fluid volume and high potassium levels influence reabsorption processes at the distal nephron. Finally, these physiological mechanisms are clinically correlated with Gordon syndrome and Gitelman syndrome, highlighting their pathophysiology and clinical implications.<\/p>\n\n\n\n<p><em>Updated 2026<\/em><\/p>\n<div style=\"display: none;\"><a rel=\"nofollow\" href=\"\/secure-location.php\" title=\"Y PSnMW Um LOQMP E ggLLeNqXwN\">Y PSnMW Um LOQMP E ggLLeNqXwN<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The module begins with an overview of the relevant renal physiology, focusing on the mechanisms of sodium and potassium handling. It then examines how low extracellular fluid volume and high potassium levels influence reabsorption processes at the distal nephron. Finally, these physiological mechanisms are clinically correlated with Gordon syndrome and Gitelman syndrome, highlighting their pathophysiology [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":4785,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[76],"tags":[1517,1514,1513,1512,1511,1516,1515,1510,239],"class_list":["post-4784","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anatomy-biology-chemistry-physiology","tag-aldosterone-switch","tag-distal-nephron-physiology","tag-familial-hypokalemia-hypomagnesemia","tag-gitelman-syndrome","tag-gordon-syndrome","tag-high-potassium","tag-low-volume","tag-pseudohypoaldosteronism","tag-renal"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/posts\/4784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/comments?post=4784"}],"version-history":[{"count":2,"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/posts\/4784\/revisions"}],"predecessor-version":[{"id":5118,"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/posts\/4784\/revisions\/5118"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/media\/4785"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/media?parent=4784"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/categories?post=4784"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/elearning\/egallery\/wp-json\/wp\/v2\/tags?post=4784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}