David Wan-Cheng Li, Ph.D.

Associate Professor

Li David


Molecular and Cellular Biology of Ocular Development and Diseases 

Research Interests:

Signal Transduction Pathways in Ocular Development and Diseases, and Cancer

Dr. Li’s lab uses the state-of-the-art molecular and cellular biology techniques, imaging technology, transgenic mice and zebrafish in vivo system, organ culture, primary culture and established cell line in vitro systems to explore functional mechanisms of the protein serine/threonine phosphatases-1 and -2A, the mitogen-activated protein kinases, the small heat shock proteins, alpha-crystallins, and small ubiquitin-like modifiers (SUMO1/2/3) in regulating development of the ocular system components (lens and retina), pathogenesis and treatment of the major ocular diseases (cataractogenesis, macular degeneration, and glaucoma, etc).  Dr. Li’s laboratory also studies the roles of Pax-6, PP-2A and alphaA-crystallin in cancer development and treatment. 

Undergraduate Education:

B.Sc., Hunan Normal University, Changsha, Hunan, China 

Graduate Education:

M.Sc., Hunan Normal University, Changsha, Hunan, China
Ph.D., University of Washington, Seattle, WA, USA 

Postgraduate Training:

Columbia University Medical Center in New York City, NY, USA 



Learn more about Dr. Li’s research