Guda Lab

Research Overview

Our laboratory nurtures a wide range of research projects related to Genomics, Bioinformatics, Systems Biology and Personal Medicine. The major research projects in my laboratory can be grouped into three broad areas: (i) Development of novel algorithms for analyzing different types of biomolecular data, followed by experimental validation and development of software and web application tools; (ii) Building data analysis pipelines for processing a variety of high-throughput ‘omics’ datasets (ExomeSeq, RNASeq, ChIPseq, methylation data, miRNA arrays and proteomics data); and (iii) Cancer genomics projects that involve integrative data analysis of molecular data across large populations, identification of molecular subtypes of cancers and functional characterization of genes and gene products identified from these studies. Some of the current research projects in my lab include analysis of breast, pancreatic and glioblastoma cancer genomics data obtained from The Cancer Genome Atlas (TCGA) project, development of novel tools for detecting fusion genes and tumor heterogeneity, and metagenomic profiling of human microbiomes. 

Guda lab 2017
From Left: Adam Cornish, Meng Niu, Matthew Cserhati, Abrar Albahrani, Kristin Wipfler, Nitish Mishra, Sanjit Pandey, Navodita Upadhyay, Yeong Kim, Jasjit Banwait, Siddesh Southekal, Duc Le, Peng Xiao, Neetha Vellichiramma, Babu Guda

Lab Members:

Abrar Albahrani
Adam S Cornish - Ph.D. Student
Babu Guda - Professor
Duc Le - Bioinformatics Programmer
Jasjit Banwait - Programmer Analyst
Meng Niu - Bioinformatics Programmer
Nagavardhini Avuthu - Ph.D. Student 
Neetha Vellichiramma - Instructor
Nitish Mishra - Instructor
Peng Xiao - Associate Professor
Sanjit Pandey - Senior Bioinformatics Programmer/Data Analyst
Siddesh Southekal - Ph.D. Student 
Yeong Kim - Assistant professor

Lab Website

Lab Publications (PubMed)