Megan E. Bosch
Megan Bosch

Megan E. Bosch

Ph.D. in Pharmacology & Experimental Neuroscience

NIH Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship (2015-2017)

The NIH National Institute of Neurological Disorders and Stroke (NINDS) provides National Research Service Award (NRSA) predoctoral training fellowships (F31) to promising applicants with the potential to become productive, independent investigators in the field of neuroscience. Megan Bosch was awarded a prestigious F31 award for her project, entitled “Perturbed glutamate homeostasis induces neuron death in Juvenile Batten Disease.”  She is investigating disruptions in metabolic pathways responsible for glutamate regulation in astrocytes and neurons, which are implicated in excessive glutamate levels and neuron excitotoxicity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL). She will also explore the ability of promising therapeutic agents to restore critical glutamate homeostatic pathways in a mouse model of JCNL, with the long-term goal of extending the quality of life for children suffering from JNCL. Megan completed her dissertation research under the mentorship of Tammy Kielian, Ph.D., receiving the Ph.D. degree in December 2017.