Nicholas A. Wood

Nicholas Wood

Nicholas A. Wood

PhD Candidate in IGPBS - Immunology, Pathology & Infectious Disease

NIAID Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship (2021-2023)

The NIH National Institute of Allergy and Infectious Diseases (NIAID) offers Kirschstein National Research Service Award Individual Predoctoral Fellowships (F31 NSRAs) to enable promising students to obtain individualized, mentored research training from outstanding faculty sponsors while conducting dissertation research in scientific health-related fields relevant to the mission of the Institute. Nick Wood has been awarded a 2-year F31 NSRA from the NIAID for his project, “Elucidation of the Role of Chlamydial ClpX During Development and Differentiation.” Chlamydia trachomatis undergoes a complex developmental cycle in which the bacteria differentiate between two functionally and morphologically distinct forms. Because these differentiation events are not preceded by division events that re-distribute proteins, Nick has hypothesized that proteomic turnover between developmental forms is critical to this process and that the Clp protease system serves as the primary mechanism for turnover of cytosolic proteins. By characterizing the molecular underpinnings of these transitions, this work will potentially open the door to targeted therapeutic strategies. Nick is a PhD Candidate in IGPBS – Immunology, Pathology & Infectious Disease, pursuing his dissertation research under the mentorship of Scot P. Ouellette, PhD, in the Department of Pathology & Microbiology.