Richard Lee Sleightholm

Richard Sleightholm

Richard Lee Sleightholm

PhD in Pharmaceutical Sciences

NIH Ruth L. Kirschstein National Research Service Award Individual Predoctotal Fellowship (2018-2021)

The National Cancer Institute Ruth L. Kirschstein National Research Service Award (NRSA) for Individual Predoctoral Fellows (F31) supports promising doctoral candidates who will perform dissertation research and training for a PhD degree in a scientific health-related field relevant to the mission of the NCI. Richard Lee Sleightholm, an MD/PhD Scholar at UNMC, has been awarded a 3-year F31 NSRA from the National Cancer Institute for his project entitled “Chloroquine Drug Delivery System for Sensitization of Pancreatic Cancer to Improve Oxaliplatin Efficacy.”  Recognizing that development of resistance to chemotherapeutics contributes immensely to the poor outcomes observed in those diagnosed with pancreatic cancer, Lee’s research aims to identify more effective treatment options. The goal is to explore a new class of hydroxychloroquine-modified drug delivery systems that can sensitize pancreatic tumors to traditional therapies while simultaneously delivering a chemotherapeutic to pancreatic tumors. Lee completed his dissertation research under the direction of David Oupicky, PhD, in the Department of Pharmaceutical Sciences, receiving the PhD degree in May 2019. He will pursue the final two years of his medical school training at UNMC.