{"id":10759,"date":"2025-11-05T16:40:44","date_gmt":"2025-11-05T22:40:44","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=10759"},"modified":"2025-11-05T16:40:47","modified_gmt":"2025-11-05T22:40:47","slug":"mit-study-finds-targets-for-a-new-tuberculosis-vaccine","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2025\/11\/05\/mit-study-finds-targets-for-a-new-tuberculosis-vaccine\/","title":{"rendered":"MIT study finds targets for a new tuberculosis vaccine"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/news.mit.edu\/2025\/mit-study-finds-targets-new-tuberculosis-vaccine-1105\">MIT<\/a> Using these antigens, researchers plan to develop vaccine candidates that they hope would stimulate a strong immune response against the world\u2019s deadliest pathogen. A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world\u2019s deadliest infectious disease.<\/p>\n\n\n\n<p>In the new study, a team of MIT biological engineers was able to identify a handful of immunogenic peptides, out of more than 4,000 bacterial proteins, that appear to stimulate a strong response from a type of T cells responsible for orchestrating immune cells\u2019 response to infection.<\/p>\n\n\n\n<p>There is currently only one vaccine for tuberculosis, known as BCG, which is a weakened version of a bacterium that causes TB in cows.&nbsp;This vaccine is widely administered in some parts of the world, but it poorly protects adults against pulmonary TB. Worldwide, tuberculosis kills more than 1 million people every year.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>MIT Using these antigens, researchers plan to develop vaccine candidates that they hope would stimulate a strong immune response against the world\u2019s deadliest pathogen. A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world\u2019s deadliest infectious disease. In the new study, a [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[8],"tags":[],"class_list":["post-10759","post","type-post","status-publish","format-standard","hentry","category-vaccine-headlines"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/10759","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=10759"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/10759\/revisions"}],"predecessor-version":[{"id":10760,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/10759\/revisions\/10760"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=10759"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=10759"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=10759"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}