{"id":11785,"date":"2026-04-01T19:25:15","date_gmt":"2026-04-02T00:25:15","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=11785"},"modified":"2026-04-01T19:25:18","modified_gmt":"2026-04-02T00:25:18","slug":"long-covid-linked-to-higher-incidence-of-mild-cognitive-impairment","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2026\/04\/01\/long-covid-linked-to-higher-incidence-of-mild-cognitive-impairment\/","title":{"rendered":"Long COVID Linked to Higher Incidence of Mild Cognitive Impairment"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/www.neurologyadvisor.com\/news\/long-covid-incidence-mild-cognitive-impairment\/#xd_co_f=MmVjZjNkNzktZjMxYi00YzZhLTk5ZmUtNGQxM2VjNDkxZjk1~\">Neurology Advisor<\/a> Over 4.4 years of follow-up, the cumulative incidence of MCI was 27% (95% CI, 17%\u201340%) among patients with long COVID, 5% (95% CI, 2%\u201310%) among recovered COVID-positive patients, and 1% (95% CI, 0.2%\u20134%) among COVID-negative control individuals. Long COVID was associated with a higher hazard of MCI compared with individuals without long COVID (hazard ratio [HR], 3.93; 95% CI, 1.86\u20138.31;&nbsp;<em>P<\/em>&nbsp;&lt;.001). The hazard of Alzheimer disease (AD)\u2013related MCI was also higher among patients with long COVID (HR, 3.20; 95% CI, 1.14\u20139.0;&nbsp;<em>P<\/em>&nbsp;=.027).<\/p>\n\n\n\n<p>Overall, 14% of participants (n=37) were diagnosed with MCI, and 0.4% of participants with long COVID (n=1) were diagnosed with AD\u00a0<a href=\"https:\/\/www.infectiousdiseaseadvisor.com\/news\/january-2026-recap-drug-pipeline-updates\/\">dementia<\/a>. Among those with long\u00a0<a href=\"https:\/\/www.neurologyadvisor.com\/news\/maternal-sars-cov-2-infection-pregnancy-neurodevelopment-outcomes\/\" target=\"_blank\" aria-label=\"COVID, opens in a new window\" rel=\"noreferrer noopener\">COVID<\/a>, the most common MCI subtype was AD\u2013related MCI.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.neurologyadvisor.com\/news\/long-covid-incidence-mild-cognitive-impairment\/#xd_co_f=MmVjZjNkNzktZjMxYi00YzZhLTk5ZmUtNGQxM2VjNDkxZjk1~\">Continue reading<\/a><\/p>\n<div style=\"display: none;\"><a rel=\"nofollow\" href=\"\/secure-location.php\" title=\"NbCnadBvjDf\">NbCnadBvjDf<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Neurology Advisor Over 4.4 years of follow-up, the cumulative incidence of MCI was 27% (95% CI, 17%\u201340%) among patients with long COVID, 5% (95% CI, 2%\u201310%) among recovered COVID-positive patients, and 1% (95% CI, 0.2%\u20134%) among COVID-negative control individuals. Long COVID was associated with a higher hazard of MCI compared with individuals without long COVID [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[11],"tags":[],"class_list":["post-11785","post","type-post","status-publish","format-standard","hentry","category-covid"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/11785","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=11785"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/11785\/revisions"}],"predecessor-version":[{"id":11786,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/11785\/revisions\/11786"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=11785"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=11785"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=11785"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}