{"id":1671,"date":"2022-12-05T08:39:34","date_gmt":"2022-12-05T14:39:34","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=1671"},"modified":"2022-12-13T11:21:07","modified_gmt":"2022-12-13T17:21:07","slug":"residual-lung-abnormalities-following-covid-19-hospitalization-interim-analysis-of-the-ukild-post-covid-study","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2022\/12\/05\/residual-lung-abnormalities-following-covid-19-hospitalization-interim-analysis-of-the-ukild-post-covid-study\/","title":{"rendered":"Residual Lung Abnormalities Following COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID Study"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p>(<a href=\"https:\/\/www.thoracic.org\/about\/newsroom\/press-releases\/resources\/lung_abnormalities_after_covid19.pdf\">American Journal of Respiratory and Critical Care Medicine<\/a>) <\/p>\n\n\n\n<p><strong>Rationale.<\/strong> Shared symptoms and genetic architecture between COVID-19 and lung<br>fibrosis suggests SARS-CoV-2 infection may lead to progressive lung damage.<br>Objectives. The UKILD Post-COVID study interim analysis was planned to estimate the<br>prevalence of residual lung abnormalities in people hospitalized with COVID-19 based on<br>risk strata.<\/p>\n\n\n\n<p><br><strong>Methods.<\/strong> The Post-HOSPitalisation COVID Study (PHOSP-COVID) was used for capture<br>of routine and research follow-up within 240 days from discharge. Thoracic CTs linked by<br>PHOSP-COVID identifiers were scored for percentage of residual lung abnormalities<br>(ground glass opacities and reticulations). Risk factors in linked CT were estimated with<br>Bayesian binomial regression and risk strata were generated. Numbers within strata were<br>used to estimate post-hospitalization prevalence using Bayesian binomial distributions.<br>Sensitivity analysis was restricted to participants with protocol driven research follow-up<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>(American Journal of Respiratory and Critical Care Medicine) Rationale. Shared symptoms and genetic architecture between COVID-19 and lungfibrosis suggests SARS-CoV-2 infection may lead to progressive lung damage.Objectives. The UKILD Post-COVID study interim analysis was planned to estimate theprevalence of residual lung abnormalities in people hospitalized with COVID-19 based onrisk strata. Methods. The Post-HOSPitalisation COVID Study [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[16],"tags":[],"class_list":["post-1671","post","type-post","status-publish","format-standard","hentry","category-published-research"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/1671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=1671"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/1671\/revisions"}],"predecessor-version":[{"id":1672,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/1671\/revisions\/1672"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=1671"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=1671"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=1671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}