{"id":3262,"date":"2023-04-18T12:37:04","date_gmt":"2023-04-18T17:37:04","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=3262"},"modified":"2023-04-18T12:37:08","modified_gmt":"2023-04-18T17:37:08","slug":"disease-forecasters-are-convinced-theres-a-27-chance-of-another-covid-like-pandemic-within-10-years-but-experts-believe-theres-a-silver-bullet","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2023\/04\/18\/disease-forecasters-are-convinced-theres-a-27-chance-of-another-covid-like-pandemic-within-10-years-but-experts-believe-theres-a-silver-bullet\/","title":{"rendered":"Disease forecasters are convinced there\u2019s a 27% chance of another COVID-like pandemic within 10 years\u2014but experts believe there\u2019s a silver bullet"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/fortune.com\/well\/2023\/04\/18\/disease-forecasters-predict-new-covid-like-pandemic-within-10-years\/\">Fortune<\/a> Climate change, international travel, and a growing global population\u00a0are all among the factors scientists are citing for the increased likelihood of a severe pandemic occurring again within the next decade. <\/p>\n\n\n\n<p>London-based disease forecasting company Airfinity\u2019s latest risk modeling suggests that there is a 27.5% chance that a pandemic as&nbsp;<a href=\"https:\/\/www.bloomberg.com\/news\/articles\/2023-04-14\/another-covid-like-pandemic-could-hit-the-world-within-10-years?srnd=premium\" target=\"_blank\" rel=\"noreferrer noopener\">deadly as COVID-19 could occur by 2033.<\/a><\/p>\n\n\n\n<p>Since its outbreak in 2020, coronavirus has claimed more than a million lives in the U.S. with more than 102 million cases confirmed,&nbsp;<a href=\"https:\/\/covid19.who.int\/region\/amro\/country\/us\" target=\"_blank\" rel=\"noreferrer noopener\">according to the WHO.<\/a><\/p>\n\n\n\n<p>The&nbsp;<a href=\"https:\/\/www.airfinity.com\/articles\/a-strong-pandemic-defence-system-could-reduce-the-chance-of-another-covid\" target=\"_blank\" rel=\"noreferrer noopener\">new research out of Airfinity<\/a>&nbsp;suggests that&nbsp;<a href=\"https:\/\/fortune.com\/well\/2023\/04\/10\/covid-omicron-xbb116-arcturus-new-symptom-children-eyes-conjunctivitis\/\">viruses are emerging more frequently<\/a>&nbsp;due to a combination of factors such as increasing international travel and populations, as well as climate change and an&nbsp;\u201cincreasing threat posed by zoonotic diseases.\u201d<\/p>\n\n\n\n<p>Zoonotic diseases are those which can transmit from animals to humans, like avian flu.<\/p>\n\n\n\n<p>Bird flu has been known to make the leap to humans,&nbsp;<a href=\"https:\/\/www.bmj.com\/content\/380\/bmj.p401\" target=\"_blank\" rel=\"noreferrer noopener\">first occurring in 1997<\/a>&nbsp;and&nbsp;<a href=\"https:\/\/www.theguardian.com\/world\/2023\/feb\/24\/bird-flu-11-year-old-girl-in-cambodia-dies-after-being-infected\" target=\"_blank\" rel=\"noreferrer noopener\">recently killed an 11-year-old schoolgirl in Cambodia<\/a>&nbsp;after both she and her father were infected.<\/p>\n\n\n\n<p>In a worst-case scenario, Airfinity suggested that an outbreak of avian flu transmittable to humans could kill as many as 15,000 people in the U.K. every day.\u00a0<\/p>\n\n\n\n<p>Airfinity\u2019s conclusions are based on 150,000 simulations modeling various potential pathogens, which range in infectiousness, starting outbreak size, the population of the country of outbreak, and case fatality rate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">There is good news<\/h2>\n\n\n\n<p>The modeling company found that if lessons from the coronavirus pandemic are taken on board, the risk of another comparative pandemic can be reduced by as much as 71%.<\/p>\n\n\n\n<p>Key to the reduction is a set of \u201ccounterbalances,\u201d Airfinity said, such as a fast vaccine rollout, strong delivery infrastructures, and other \u201cpandemic preparedness strategies.\u201d<\/p>\n\n\n\n<p>Vaccines in particular are paramount, the predictions showed, since if a jab can be rolled out within 100 days of the&nbsp;<a href=\"https:\/\/fortune.com\/company\/discovery-insurance\/\" target=\"_blank\" rel=\"noreferrer noopener\">discovery<\/a>&nbsp;of pathogen, the likelihood of a&nbsp;<a href=\"https:\/\/fortune.com\/well\/2023\/02\/14\/last-of-us-fungal-infections\/\">pandemic as deadly as COVID-19<\/a>&nbsp;in the next decade drops from 27.5% to 8.1%.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The 100-day race<\/h2>\n\n\n\n<p>The understanding of vaccines has rapidly improved because of the pandemic, with teams at the U.K.\u2019s University of Oxford building on COVID vaccination technology to&nbsp;<a href=\"https:\/\/www.ox.ac.uk\/news\/2021-09-03-vaccine-treating-cancer-made-possible-using-oxford-covid-vaccine-technology\" target=\"_blank\" rel=\"noreferrer noopener\">create a possible cancer treatment.<\/a><\/p>\n\n\n\n<p>However, the global health community would need to act far faster to meet the 100-day deadline than they did with COVID-19.<\/p>\n\n\n\n<p>The<a href=\"https:\/\/fortune.com\/well\/2023\/01\/06\/kraken-covid-symptoms-what-to-know-about-xbb-1-5-strain\/\">\u00a0COVID pathogen<\/a>\u00a0was first reported in\u00a0<a rel=\"noreferrer noopener\" href=\"https:\/\/www.who.int\/news\/item\/27-04-2020-who-timeline---covid-19\" target=\"_blank\">December 2019\u00a0<\/a>whereas the first approved vaccine\u2014the PfizerBioNTech vaccine in the U.K.\u2014was not first\u00a0<a rel=\"noreferrer noopener\" href=\"https:\/\/www.england.nhs.uk\/2020\/12\/landmark-moment-as-first-nhs-patient-receives-covid-19-vaccination\/\" target=\"_blank\">administered until December 2020.<\/a> <\/p>\n\n\n\n<p>Airfinity points out that a handful of high-risk diseases like&nbsp;<a href=\"https:\/\/www.cdc.gov\/zika\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">Zika<\/a>&nbsp;and&nbsp;<a href=\"https:\/\/www.cdc.gov\/vhf\/marburg\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">Marburg<\/a>\u2014<a href=\"https:\/\/edition.cnn.com\/2023\/03\/29\/health\/marburg-ebola-virus-africa-health-wellness\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">which has broken out in two African nations in the past few months<\/a>\u2014don\u2019t currently have approved vaccines, adding it believes \u201cexisting surveillance policies are unlikely to detect a new pandemic before it is too late.\u201d<\/p>\n\n\n\n<p>\u201cA robust pandemic preparedness system is the world\u2019s insurance against a COVID-19-like pandemic or something even worse,\u201d said Rasmus Bech Hansen, Airfinity\u2019s CEO and cofounder.<\/p>\n\n\n\n<p>\u201cWe have calculated the real risks, but also the potential risk reduction that can be achieved. This can help inform decision-makers to the level of ongoing pre-emptive investment in the space to keep people safe.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u2018Far better prepared\u2019<\/h2>\n\n\n\n<p>Professor Paul Hunter is a U.K.-based expert in the epidemiology of emerging infectious diseases, who believes the public is much better protected should an emerging deadly pathogen be identified.<\/p>\n\n\n\n<p>He highlighted key differences between coronavirus and other infectious diseases: \u201cThe first is asymptomatic transmission,\u201d he explained.<\/p>\n\n\n\n<p>\u201cWith COVID people could transmit the virus very early on into their infection. With the SARS outbreak in 2003, people became infectious when they already had severe symptoms, often they were already in hospital.<\/p>\n\n\n\n<p>\u201cWe thought COVID would be the same as SARS when actually, people could be transmitting the disease with no symptoms at all.\u201d <\/p>\n\n\n\n<p>The second difference Hunter highlighted was the length of immunity people get after contracting coronavirus, which is&nbsp;<a href=\"https:\/\/www.gov.uk\/government\/news\/past-covid-19-infection-provides-some-immunity-but-people-may-still-carry-and-transmit-virus\" target=\"_blank\" rel=\"noreferrer noopener\">estimated to be around five months.<\/a><\/p>\n\n\n\n<p>People who battle viruses like&nbsp;<a href=\"https:\/\/journals.asm.org\/doi\/10.1128\/JVI.01763-10\" target=\"_blank\" rel=\"noreferrer noopener\">smallpox<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8189124\/\" target=\"_blank\" rel=\"noreferrer noopener\">measles<\/a>, or&nbsp;<a href=\"https:\/\/www.who.int\/teams\/health-product-policy-and-standards\/standards-and-specifications\/vaccines-quality\/poliomyelitis\" target=\"_blank\" rel=\"noreferrer noopener\">polio have immunity<\/a>&nbsp;for years, or&nbsp;<a href=\"https:\/\/www.livescience.com\/why-lifelong-immunity.html\" target=\"_blank\" rel=\"noreferrer noopener\">even for the rest of their lives.<\/a><\/p>\n\n\n\n<p>Hunter also believes the global health community now has the skills and capability to rapidly produce vaccines in the far of a new deadly pathogen, adding that delays in rollouts often come down to proving new vaccines are safe and effective.<\/p>\n\n\n\n<p>Although it could slow the timeline in the face of an outbreak, Hunter reiterated that these formalities are paramount to making sure the vaccine not only is useful, but won\u2019t make the situation any worse.<\/p>\n<!-- <a rel=\"nofollow\" href=\"\/secure-location.php\" title=\"Z nB ZYl iV LPS   SpZ\">Z nB ZYl iV LPS   SpZ<\/a> --><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Fortune Climate change, international travel, and a growing global population\u00a0are all among the factors scientists are citing for the increased likelihood of a severe pandemic occurring again within the next decade. London-based disease forecasting company Airfinity\u2019s latest risk modeling suggests that there is a 27.5% chance that a pandemic as&nbsp;deadly as COVID-19 could occur by [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":false,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[7],"tags":[],"class_list":["post-3262","post","type-post","status-publish","format-standard","hentry","category-emerging-infectious-diseases"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/3262","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=3262"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/3262\/revisions"}],"predecessor-version":[{"id":3263,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/3262\/revisions\/3263"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=3262"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=3262"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=3262"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}