{"id":4848,"date":"2023-10-04T06:44:44","date_gmt":"2023-10-04T11:44:44","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=4848"},"modified":"2023-10-04T06:47:37","modified_gmt":"2023-10-04T11:47:37","slug":"mrna-covid-vaccines-saved-lives-and-won-a-nobel-whats-next-for-the-technology","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2023\/10\/04\/mrna-covid-vaccines-saved-lives-and-won-a-nobel-whats-next-for-the-technology\/","title":{"rendered":"mRNA COVID vaccines saved lives and won a Nobel \u2014 what&#8217;s next for the technology?"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-023-03119-x\">Nature<\/a> In just three short years, mRNA vaccines have saved millions of lives, achieved household recognition and, as of this week,\u00a0<a href=\"https:\/\/www.nature.com\/articles\/d41586-023-03046-x\">become the subject of a Nobel Prize<\/a>. Yet the field shows no signs of slowing down. <\/p>\n\n\n\n<p>In the wake of the technology\u2019s dramatic success in generating quick-turnaround COVID-19 vaccines, investors have poured billions of dollars into&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/d41586-021-00019-w\">expanding mRNA\u2019s therapeutic reach<\/a>.<\/p>\n\n\n\n<p>This influx of cash promises to fuel the research and infrastructure needed to deploy mRNA medicines in ways that could transform public health by tackling hard-to-treat infectious diseases, cancers and rare genetic disorders.<\/p>\n\n\n\n<p>\u201cThe sky\u2019s the limit,\u201d says Matthias Stephan, an immunologist at the Fred Hutchinson Cancer Research Center in Seattle, Washington. \u201cFor whatever you want to correct, or whatever you want to treat, there could be an mRNA medicine \u2014 that\u2019s the excitement.\u201d<\/p>\n\n\n\n<p><em>Nature<\/em>&nbsp;spoke to researchers about mRNA medicines on the horizon.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Curbing outbreaks: when speed is of the essence<\/h2>\n\n\n\n<p>Vaccines based on mRNA rose to fame not only for their safety and efficacy, but also for the speed with which they were developed and rolled out during the COVID-19 pandemic.<\/p>\n\n\n\n<p>The approach allows researchers to have \u201ca very potently effective vaccine in arms within weeks\u201d, says Barney Graham, who helped to develop one of the mRNA-based COVID-19 vaccines while at the US National Institutes of Health. (Graham now serves as senior adviser for global health equity at Morehouse School of Medicine in Atlanta, Georgia.)<\/p>\n\n\n\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-023-03119-x\">Continue reading<\/a><\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Nature In just three short years, mRNA vaccines have saved millions of lives, achieved household recognition and, as of this week,\u00a0become the subject of a Nobel Prize. Yet the field shows no signs of slowing down. In the wake of the technology\u2019s dramatic success in generating quick-turnaround COVID-19 vaccines, investors have poured billions of dollars [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[21],"tags":[],"class_list":["post-4848","post","type-post","status-publish","format-standard","hentry","category-featured"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/4848","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=4848"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/4848\/revisions"}],"predecessor-version":[{"id":4849,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/4848\/revisions\/4849"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=4848"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=4848"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=4848"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}