{"id":5153,"date":"2023-11-07T19:06:20","date_gmt":"2023-11-08T01:06:20","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=5153"},"modified":"2023-11-07T19:06:24","modified_gmt":"2023-11-08T01:06:24","slug":"dengue-is-spreading-can-new-vaccines-and-antivirals-halt-its-rise","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2023\/11\/07\/dengue-is-spreading-can-new-vaccines-and-antivirals-halt-its-rise\/","title":{"rendered":"Dengue is spreading. Can new vaccines and antivirals halt its rise?"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-023-03453-0\">Nature<\/a> <\/p>\n\n\n\n<p>Dengue is on the march. This year, more than 4.2 million cases of the disease,&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/d41586-023-02423-w\">which is caused by a virus transmitted by mosquitoes<\/a>, had been reported by 2 October, compared with&nbsp;<a href=\"https:\/\/news.un.org\/en\/story\/2023\/07\/1138962\">half a million in 2000<\/a>. And the disease, which was once confined to the tropics, is spreading to new locations around the world, including&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/d41586-023-03407-6\">southern Europe<\/a>.<\/p>\n\n\n\n<p>There is no specific treatment for dengue, which is also known as breakbone fever and can cause fever, bone pain and even death. The available vaccines have&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/d41586-022-03546-2\">important limitations<\/a>, and&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/d41586-020-02492-1\">controlling the mosquitoes<\/a>&nbsp;that transmit the disease is challenging.<\/p>\n\n\n\n<p>But scientists are not sitting idle. At the&nbsp;<a href=\"https:\/\/www.astmh.org\/annual-meeting\">annual meeting<\/a>&nbsp;of the American Society of Tropical Medicine and Hygiene, held in Chicago, Illinois, last month, researchers shared the latest results of their efforts to develop vaccines, antiviral medications and mosquito-control methods to curb the disease. Every available tool is needed, they say.<\/p>\n\n\n\n<p>\u201cWe\u2019re seeing the emergence of dengue in areas where we\u2019ve never seen it before,\u201d Adam Waickman, an immunologist at SUNY Upstate Medical University in Syracuse, New York, said during the meeting. \u201cEffective dengue control is going to require multi-layered efforts.\u201d<\/p>\n\n\n\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-023-03453-0\">Continue reading<\/a><\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Nature Dengue is on the march. This year, more than 4.2 million cases of the disease,&nbsp;which is caused by a virus transmitted by mosquitoes, had been reported by 2 October, compared with&nbsp;half a million in 2000. And the disease, which was once confined to the tropics, is spreading to new locations around the world, including&nbsp;southern [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":5154,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[61],"tags":[],"class_list":["post-5153","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dengue"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-content\/uploads\/2023\/11\/Screenshot-2023-11-07-at-20.04.47.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/5153","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=5153"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/5153\/revisions"}],"predecessor-version":[{"id":5155,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/5153\/revisions\/5155"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media\/5154"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=5153"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=5153"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=5153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}