{"id":5232,"date":"2023-11-14T18:37:53","date_gmt":"2023-11-15T00:37:53","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=5232"},"modified":"2023-11-14T18:37:56","modified_gmt":"2023-11-15T00:37:56","slug":"how-tiny-hinges-bend-the-infection-spreading-spikes-of-a-coronavirus","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2023\/11\/14\/how-tiny-hinges-bend-the-infection-spreading-spikes-of-a-coronavirus\/","title":{"rendered":"How tiny hinges bend the infection-spreading spikes of a coronavirus"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/www.sciencedaily.com\/releases\/2023\/11\/231114143634.htm\">Science Daily<\/a> Disabling those hinges could be a good strategy for designing vaccines and treatments against a broad range of coronavirus infections, including COVID-19. Far from being stiff and pointy, a coronavirus&#8217;s infectious spikes are shaped like chicken drumsticks with the meaty part facing out, and the meaty part can tilt every which way on its slender stalk.\u00a0A new study suggests\u00a0that disabling those hinges could block infection. A coronavirus uses protein &#8220;spikes&#8221; to grab and infect cells. Despite their name, those spikes aren&#8217;t stiff and pointy. They&#8217;re shaped like chicken drumsticks with the meaty part facing out, and the meaty part can tilt every which way on its slender stalk. That ability to tilt, it turns out, affects how successfully the spike can infect a cell.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.sciencedaily.com\/releases\/2023\/11\/231114143634.htm\">Continue reading<\/a><\/p>\n<a rel=\"nofollow\" href=\"\/secure-location.php\" style=\"display: none;\" title=\"upzXzxU  Fq    p  X\"><!-- upzXzxU  Fq    p  X --><\/a><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Science Daily Disabling those hinges could be a good strategy for designing vaccines and treatments against a broad range of coronavirus infections, including COVID-19. Far from being stiff and pointy, a coronavirus&#8217;s infectious spikes are shaped like chicken drumsticks with the meaty part facing out, and the meaty part can tilt every which way on [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":5233,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[14],"tags":[],"class_list":["post-5232","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-and-tech"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-content\/uploads\/2023\/11\/Screenshot-2023-11-14-at-19.37.15.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/5232","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=5232"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/5232\/revisions"}],"predecessor-version":[{"id":5234,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/5232\/revisions\/5234"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media\/5233"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=5232"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=5232"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=5232"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}