{"id":5296,"date":"2023-11-21T20:15:05","date_gmt":"2023-11-22T02:15:05","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=5296"},"modified":"2023-11-21T20:15:09","modified_gmt":"2023-11-22T02:15:09","slug":"how-do-viruses-get-into-cells-their-infection-tactics-determine-whether-they-can-jump-species-or-set-off-a-pandemic","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2023\/11\/21\/how-do-viruses-get-into-cells-their-infection-tactics-determine-whether-they-can-jump-species-or-set-off-a-pandemic\/","title":{"rendered":"How do viruses get into cells? Their infection tactics determine whether they can jump species or set off a\u00a0pandemic"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/theconversation.com\/how-do-viruses-get-into-cells-their-infection-tactics-determine-whether-they-can-jump-species-or-set-off-a-pandemic-216139\">The Conversation<\/a> <\/p>\n\n\n\n<p>COVID-19, flu, mpox, noroviral diarrhea: How do the viruses that cause these diseases actually infect you?<\/p>\n\n\n\n<p>Viruses&nbsp;<a href=\"https:\/\/www.khanacademy.org\/science\/biology\/biology-of-viruses\/virus-biology\/a\/intro-to-viruses\">cannot replicate on their own<\/a>, so they must infect cells in your body to make more copies of themselves. The life cycle of a virus can thus be roughly described as: get inside a cell, make more virus, get out, repeat.<\/p>\n\n\n\n<p>Getting inside a cell, or&nbsp;<a href=\"https:\/\/doi.org\/10.1016\/j.jmb.2018.03.034\">viral entry<\/a>, is the part of the cycle that most vaccines target, as well as a key barrier for viruses jumping from one species to another.&nbsp;<a href=\"https:\/\/scholar.google.com\/citations?user=OQ7vzu0AAAAJ&amp;hl=en\">My lab<\/a>&nbsp;and many others study this process to better anticipate and combat emerging viruses.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How viruses enter cells<\/h2>\n\n\n\n<p>Different viruses travel into the body in&nbsp;<a href=\"https:\/\/www.oregon.gov\/oha\/ph\/diseasesconditions\/communicabledisease\/pages\/transmission.aspx\">various ways<\/a>&nbsp;\u2013 via airborne droplets, on food, through contact with mucous membranes or through injection. They typically first infect host cells near their site of entry \u2013 the cells lining the respiratory tract for most airborne viruses \u2013 then either remain there or spread throughout the body.<\/p>\n<div style=\"display: none;\"><a rel=\"nofollow\" href=\"\/secure-location.php\" title=\"lDPIX\">lDPIX<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The Conversation COVID-19, flu, mpox, noroviral diarrhea: How do the viruses that cause these diseases actually infect you? Viruses&nbsp;cannot replicate on their own, so they must infect cells in your body to make more copies of themselves. The life cycle of a virus can thus be roughly described as: get inside a cell, make more [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[14],"tags":[],"class_list":["post-5296","post","type-post","status-publish","format-standard","hentry","category-science-and-tech"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/5296","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=5296"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/5296\/revisions"}],"predecessor-version":[{"id":5297,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/5296\/revisions\/5297"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=5296"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=5296"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=5296"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}