{"id":6164,"date":"2024-03-26T21:08:44","date_gmt":"2024-03-27T02:08:44","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=6164"},"modified":"2024-03-26T21:08:48","modified_gmt":"2024-03-27T02:08:48","slug":"people-more-often-are-origin-of-infectious-diseases-in-animals-than-vice-versa-data-suggest","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2024\/03\/26\/people-more-often-are-origin-of-infectious-diseases-in-animals-than-vice-versa-data-suggest\/","title":{"rendered":"People more often are origin of infectious diseases in animals than vice versa, data suggest"},"content":{"rendered":"
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CIDRAP<\/a> <\/p>\n\n\n\n

People pass twice as many viruses to domestic and wild animals than animals pass to people, concludes a study<\/a> today in Nature Ecology & Evolution<\/em>.<\/p>\n\n\n\n

University College London (UCL) researchers analyzed genomic data on nearly 12 million viruses in 32 viral families using network and evolutional analyses to characterize the mutations behind recent vertebrate species jumps.<\/p>\n\n\n\n

Most emerging and re-emerging infectious diseases are caused by viruses that circulate naturally in nonhuman vertebrates. “When these viruses cross over into humans, they can cause disease outbreaks, epidemics and pandemics,” they authors wrote. “While zoonotic host jumps have been extensively studied from an ecological perspective, little attention has gone into characterizing the evolutionary drivers and correlates underlying these events.”<\/p>\n\n\n\n

Viral strains that jump species had to mutate more<\/h3>\n\n\n\n

About twice as many species jumps were inferred to be from people to animals rather than the other way round, a pattern consistent across most viral families. “We further observe that the extent of adaptation associated with a host jump is lower for viruses with broader host ranges,” they wrote. “Finally, we show that the genomic targets of natural selection associated with host jumps vary across different viral families, with either structural or auxiliary genes being the prime targets of selection.”<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

CIDRAP People pass twice as many viruses to domestic and wild animals than animals pass to people, concludes a study today in Nature Ecology & Evolution. University College London (UCL) researchers analyzed genomic data on nearly 12 million viruses in 32 viral families using network and evolutional analyses to characterize the mutations behind recent vertebrate species jumps. Most emerging and re-emerging […]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[29],"tags":[],"class_list":["post-6164","post","type-post","status-publish","format-standard","hentry","category-zoonotic-diseases"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/6164","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=6164"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/6164\/revisions"}],"predecessor-version":[{"id":6165,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/6164\/revisions\/6165"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=6164"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=6164"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=6164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}