{"id":6482,"date":"2024-04-25T16:55:09","date_gmt":"2024-04-25T21:55:09","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=6482"},"modified":"2024-04-30T16:56:25","modified_gmt":"2024-04-30T21:56:25","slug":"how-bird-flu-virus-fragments-get-into-milk-sold-in-stores-and-what-the-spread-of-h5n1-in-cows-means-for-the-dairy-industry-and-milk-drinkers","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2024\/04\/25\/how-bird-flu-virus-fragments-get-into-milk-sold-in-stores-and-what-the-spread-of-h5n1-in-cows-means-for-the-dairy-industry-and-milk-drinkers\/","title":{"rendered":"How bird flu virus fragments get into milk sold in stores, and what the spread of H5N1 in cows means for the dairy industry and milk\u00a0drinkers"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/theconversation.com\/how-bird-flu-virus-fragments-get-into-milk-sold-in-stores-and-what-the-spread-of-h5n1-in-cows-means-for-the-dairy-industry-and-milk-drinkers-228689\">The Conversation<\/a> <\/p>\n\n\n\n<p><em>The discovery of&nbsp;<a href=\"https:\/\/www.fda.gov\/food\/alerts-advisories-safety-information\/updates-highly-pathogenic-avian-influenza-hpai\">fragments of avian flu<\/a>&nbsp;virus in milk sold in U.S. stores, including in&nbsp;<a href=\"https:\/\/www.fda.gov\/food\/alerts-advisories-safety-information\/updates-highly-pathogenic-avian-influenza-hpai\">about 20% of samples<\/a>&nbsp;in initial testing across the country, suggests that the H5N1 virus may be more widespread in dairy cattle than previously realized.<\/em><\/p>\n\n\n\n<p><em>The Food and Drug Administration, which announced the early results from its nationally representative sampling on April 25, 2024, was quick to stress that it&nbsp;<a href=\"https:\/\/www.fda.gov\/food\/alerts-advisories-safety-information\/updates-highly-pathogenic-avian-influenza-hpai\">believes the commercial milk supply is safe<\/a>. The FDA said initial tests&nbsp;<a href=\"https:\/\/www.fda.gov\/food\/alerts-advisories-safety-information\/updates-highly-pathogenic-avian-influenza-hpai\">did not detect<\/a>&nbsp;any live, infectious virus. However, highly pathogenic avian influenza virus can make cows sick, and the flu virus\u2019s presence in herds in several states and&nbsp;<a href=\"https:\/\/www.usda.gov\/media\/press-releases\/2024\/04\/24\/usda-actions-protect-livestock-health-highly-pathogenic-h5n1-avian\">new federal restrictions<\/a>&nbsp;on the movement of dairy cows between states are putting economic pressure on farmers.<\/em><\/p>\n\n\n\n<p><em>Five experts in infectious diseases in cattle from the University of California, Davis \u2013&nbsp;<a href=\"https:\/\/scholar.google.com\/citations?user=7b54zfwAAAAJ&amp;hl=en&amp;oi=ao\">Noelia Silva del Rio<\/a>,&nbsp;<a href=\"https:\/\/scholar.google.com\/citations?user=zPLba9MAAAAJ&amp;hl=en\">Terry Lehenbauer<\/a>,&nbsp;<a href=\"https:\/\/scholar.google.com\/citations?hl=en&amp;user=pI1uL2sAAAAJ\">Richard Pereira<\/a>,&nbsp;<a href=\"https:\/\/scholar.google.com\/citations?hl=en&amp;user=8jC3lRwAAAAJ\">Robert Moeller<\/a>&nbsp;and&nbsp;<a href=\"https:\/\/www.vetmed.ucdavis.edu\/faculty\/todd-edward-cornish\">Todd Cornish<\/a>&nbsp;\u2013 explain what the test results mean, how bird flu can spread to cattle and the impact on the industry.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What are viral fragments of avian flu, and can they pose risks to people?<\/h2>\n\n\n\n<p>It\u2019s crucial to understand that the presence of viral fragments of H5N1 doesn\u2019t indicate the presence of intact virus particles that could cause disease.<\/p>\n\n\n\n<p>The commercial milk supply&nbsp;<a href=\"https:\/\/www.fda.gov\/food\/milk-guidance-documents-regulatory-information\/questions-and-answers-regarding-milk-safety-during-highly-pathogenic-avian-influenza-hpai-outbreaks\">maintains safety<\/a>&nbsp;through two critical measures:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>First, milk sourced from sick animals is promptly diverted or disposed of, ensuring it does not enter the food chain.<\/li>\n\n\n\n<li>Second, all milk at grocery stores is heat treated to reduce pathogen load to safe levels, mainly by pasteurization. Pasteurization has been shown to\u00a0<a href=\"https:\/\/doi.org\/10.3390\/microbiolres13040060\">effectively inactivate H5N1 in eggs<\/a>, and that process occurs at a lower temperature than is used for milk.<\/li>\n<\/ul>\n\n\n\n<p>The viral fragments were detected using&nbsp;<a href=\"https:\/\/www.usgs.gov\/labs\/laboratory-for-infectious-disease-and-the-environment\/real-time-quantitative-polymerase-chain\">quantitative polymerase chain reaction testing<\/a>, which is known for its exceptional sensitivity in detecting even trace amounts of viral genetic material. These fragments are only evidence that the virus was present in the milk. They aren\u2019t evidence that the virus is biologically active.<\/p>\n\n\n\n<p>To evaluate whether the presence of the viral fragments corresponds to a virus with the capacity to replicate and cause disease, a different testing approach is necessary. Tests such as&nbsp;<a href=\"https:\/\/www.fda.gov\/food\/alerts-advisories-safety-information\/updates-highly-pathogenic-avian-influenza-hpai\">embryonated egg viability studies<\/a>&nbsp;allow scientists to assess the virus\u2019s ability to replicate by injecting a sample into an embryonated chicken egg. That type of testing is underway.<\/p>\n\n\n\n<p>On April 24, 2024, the FDA said it had found\u00a0<a href=\"https:\/\/www.fda.gov\/food\/alerts-advisories-safety-information\/updates-highly-pathogenic-avian-influenza-hpai?ftag=MSF0951a18\">no reason to change its assessment<\/a>\u00a0that the U.S. milk supply is safe. The agency does strongly advise against consuming raw milk and products derived from it because of its inherent risks of contamination with harmful pathogens, including avian flu viruses.<\/p>\n\n\n\n<p>Continue reading<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The Conversation The discovery of&nbsp;fragments of avian flu&nbsp;virus in milk sold in U.S. stores, including in&nbsp;about 20% of samples&nbsp;in initial testing across the country, suggests that the H5N1 virus may be more widespread in dairy cattle than previously realized. The Food and Drug Administration, which announced the early results from its nationally representative sampling on [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[37],"tags":[],"class_list":["post-6482","post","type-post","status-publish","format-standard","hentry","category-avian-influenza"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/6482","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=6482"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/6482\/revisions"}],"predecessor-version":[{"id":6483,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/6482\/revisions\/6483"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=6482"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=6482"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=6482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}