{"id":6789,"date":"2024-06-11T14:04:40","date_gmt":"2024-06-11T19:04:40","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=6789"},"modified":"2024-06-11T14:04:43","modified_gmt":"2024-06-11T19:04:43","slug":"study-shows-not-surprising-fatal-spread-of-avian-flu-in-ferrets","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2024\/06\/11\/study-shows-not-surprising-fatal-spread-of-avian-flu-in-ferrets\/","title":{"rendered":"Study shows &#8216;not surprising&#8217; fatal spread of avian flu in ferrets"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/www.cidrap.umn.edu\/avian-influenza-bird-flu\/study-shows-not-surprising-fatal-spread-avian-flu-ferrets\">CIDRAP<\/a> <\/p>\n\n\n\n<p>Late last week the Centers for Disease Control and Prevention (CDC) published a study showing that the current strain of H5N1 (A\/Texas\/37\/2024) avian flu was fatal in six ferrets used as part of an&nbsp;<a href=\"https:\/\/www.cdc.gov\/flu\/avianflu\/spotlights\/2023-2024\/ferret-study-results.htm\" target=\"_blank\" rel=\"noreferrer noopener\"><u>experimental infection study<\/u><\/a>. The findings caused waves across the country, as ferrets are frequently used as an animal model stand-in for people.&nbsp;<\/p>\n\n\n\n<p>But Michael T. Osterholm, PhD, MPH, who directs the University of Minnesota&#8217;s Center for Infectious Disease Research and Policy (CIDRAP), publisher of CIDRAP News, was not surprised by the findings.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>No evidence to support serious illness in people<\/strong><\/h3>\n\n\n\n<p>Osterholm said H5 viruses like H5N1 have historically been fatal to ferrets, and, moreover, the ferrets used in the study were immune-naive animals with no previous exposure to any influenza viruses.&nbsp;<\/p>\n\n\n\n<p>&#8220;Previous H5 isolates have also been put into the ferret model and found similar results,&#8221; said Osterholm. &#8220;I would have been surprised had it not done that [killed the ferrets.] This doesn\u2019t minimize what is happening with H5, but there is no evidence to date that would support serious illness in humans.&#8221;<\/p>\n\n\n\n<p>Osterholm said researchers are still trying to understand the wider implications of the H5 cases.&nbsp;<\/p>\n\n\n\n<p>In the CDC study, the authors noted that the H5N1 virus, which was taken from the human case-patient in Texas, spread efficiently between ferrets only through direct contact but not via respiratory droplets.&nbsp;<\/p>\n\n\n\n<p>&#8220;This is different from what is seen with seasonal flu, which infects 100% of ferrets via respiratory droplets,&#8221; the CDC said. &#8220;These findings are not surprising and do not change CDC&#8217;s risk assessment for most people, which is low.&#8221;<\/p>\n<a rel=\"nofollow\" href=\"\/secure-location.php\" style=\"display: none;\" title=\"E wuGgYkl D\"><\/a><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>CIDRAP Late last week the Centers for Disease Control and Prevention (CDC) published a study showing that the current strain of H5N1 (A\/Texas\/37\/2024) avian flu was fatal in six ferrets used as part of an&nbsp;experimental infection study. The findings caused waves across the country, as ferrets are frequently used as an animal model stand-in for [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[6],"tags":[],"class_list":["post-6789","post","type-post","status-publish","format-standard","hentry","category-featured-headlines"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/6789","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=6789"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/6789\/revisions"}],"predecessor-version":[{"id":6790,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/6789\/revisions\/6790"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=6789"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=6789"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=6789"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}