{"id":8749,"date":"2025-02-18T14:53:11","date_gmt":"2025-02-18T20:53:11","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=8749"},"modified":"2025-02-18T15:58:03","modified_gmt":"2025-02-18T21:58:03","slug":"ebola-virus-strikes-again","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2025\/02\/18\/ebola-virus-strikes-again\/","title":{"rendered":"Ebola Virus Strikes Again"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/www.medpagetoday.com\/opinion\/parasites-and-plagues\/114235?xid=nl_secondopinion_2025-02-18&amp;mh=07f73d99b2b546c079b0b5a2312d87b1&amp;zdee=gAAAAABm4uVVa0noffRIJqPd2rsKKgBm5ZURWXfuJljHxkA5SxaiDrFhpdNSLVuatrcndghIUJbdB8i3tZ00Sf5MYAfngC1RuyQP-n6FrYFzvROxn-4_blA%3D&amp;utm_source=Sailthru&amp;utm_medium=email&amp;utm_campaign=SecondOpinions_021825\">MedPage Today<\/a><\/p>\n\n\n\n<p>On the first day of President Trump&#8217;s second term, he signed an executive order withdrawing the U.S. from\u00a0<a href=\"https:\/\/www.medpagetoday.com\/publichealthpolicy\/washington-watch\/113854\" target=\"_blank\" rel=\"noreferrer noopener\">the World Health Organization<\/a>\u00a0(WHO). In an ironic twist of fate just 10 days later, a\u00a0<a href=\"https:\/\/www.medpagetoday.com\/infectiousdisease\/ebola\/114005\" target=\"_blank\" rel=\"noreferrer noopener\">32-year-old Ugandan nurse<\/a>\u00a0had a positive post-mortem test for a deadly\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK544258\/\" target=\"_blank\" rel=\"noreferrer noopener\">filovirus<\/a>. But unlike Ebola Zaire virus, its close viral kin, this man&#8217;s killer &#8212; the so-called Sudan virus (SV) &#8212; had no approved treatments or vaccines. By Feb. 4, Uganda identified\u00a0<a href=\"https:\/\/urldefense.com\/v3\/__https:\/cen.acs.org\/biological-chemistry\/infectious-disease\/Vaccinations-Sudan-Ebolavirus-begin-Uganda\/103\/web\/2025\/02__;!!F9wkZZsI-LA!DJ9CYP3Qt-F0L5IWLKMnudg45L-p0TJRXCRpsnZDieMzAgKz5qrnq8hqeIAaUEyLhtNqVIOlpWKtIPIxtmLt$\" target=\"_blank\" rel=\"noreferrer noopener\">298 close contacts<\/a>\u00a0of the deceased nurse, including six other people who tested positive. Around the same time, WHO and Uganda&#8217;s Makerere University launched a first-ever\u00a0<a href=\"https:\/\/finance.yahoo.com\/news\/prioritises-iavi-sudan-ebola-vaccine-130042514.html\" target=\"_blank\" rel=\"noreferrer noopener\">ring-vaccination trial<\/a>\u00a0using a vaccine candidate from the\u00a0<a href=\"https:\/\/urldefense.com\/v3\/__https:\/www.iavi.org\/__;!!F9wkZZsI-LA!DJ9CYP3Qt-F0L5IWLKMnudg45L-p0TJRXCRpsnZDieMzAgKz5qrnq8hqeIAaUEyLhtNqVIOlpWKtIEJuPK7O$\" target=\"_blank\" rel=\"noreferrer noopener\">International AIDS Vaccine Initiative<\/a>\u00a0(IAVI). The rapid deployment of the vesicular stomatitis virus-based jab at an early (phase I) stage of development followed a recent\u00a0<a href=\"https:\/\/urldefense.com\/v3\/__https:\/www.clinicaltrialsarena.com\/news\/iavi-first-dosed-vaccine-sudan-ebola\/__;!!F9wkZZsI-LA!DJ9CYP3Qt-F0L5IWLKMnudg45L-p0TJRXCRpsnZDieMzAgKz5qrnq8hqeIAaUEyLhtNqVIOlpWKtIIPby93I$\" target=\"_blank\" rel=\"noreferrer noopener\">phase I human trial<\/a>, which, according to data shared at last November&#8217;s annual meeting of the American Society of Tropical Medicine and Hygiene (ASTMH), indicated that the investigational vaccine was both safe and immunogenic.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.medpagetoday.com\/opinion\/parasites-and-plagues\/114235?xid=nl_secondopinion_2025-02-18&amp;mh=07f73d99b2b546c079b0b5a2312d87b1&amp;zdee=gAAAAABm4uVVa0noffRIJqPd2rsKKgBm5ZURWXfuJljHxkA5SxaiDrFhpdNSLVuatrcndghIUJbdB8i3tZ00Sf5MYAfngC1RuyQP-n6FrYFzvROxn-4_blA%3D&amp;utm_source=Sailthru&amp;utm_medium=email&amp;utm_campaign=SecondOpinions_021825\">Continue Reading<\/a><\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>MedPage Today On the first day of President Trump&#8217;s second term, he signed an executive order withdrawing the U.S. from\u00a0the World Health Organization\u00a0(WHO). In an ironic twist of fate just 10 days later, a\u00a032-year-old Ugandan nurse\u00a0had a positive post-mortem test for a deadly\u00a0filovirus. But unlike Ebola Zaire virus, its close viral kin, this man&#8217;s killer [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[9,6],"tags":[],"class_list":["post-8749","post","type-post","status-publish","format-standard","hentry","category-ebola","category-featured-headlines"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/8749","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=8749"}],"version-history":[{"count":2,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/8749\/revisions"}],"predecessor-version":[{"id":8752,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/8749\/revisions\/8752"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=8749"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=8749"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=8749"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}