{"id":9305,"date":"2025-04-23T13:58:31","date_gmt":"2025-04-23T18:58:31","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=9305"},"modified":"2025-04-23T13:58:34","modified_gmt":"2025-04-23T18:58:34","slug":"plasmodium-cynomolgi-potential-emergence-of-new-zoonotic-malaria-in-southeast-asia","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2025\/04\/23\/plasmodium-cynomolgi-potential-emergence-of-new-zoonotic-malaria-in-southeast-asia\/","title":{"rendered":"Plasmodium cynomolgi: potential emergence of new zoonotic malaria in Southeast Asia"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/parasitesandvectors.biomedcentral.com\/articles\/10.1186\/s13071-025-06784-1\">BMC<\/a><\/p>\n\n\n\n<p>The reported cases of\u00a0<em>Plasmodium cynomolgi<\/em>\u00a0in Southeast Asia pose a significant public health concern. Sporadic reports of human\u00a0<em>Plasmodium cynomolgi<\/em>\u00a0infections have increased in the past few years, raising attention regarding its potential impact on human populations. Further compounding this issue are the morphological similarities between\u00a0<em>P. cynomolgi<\/em>\u00a0and the human malaria parasite\u00a0<em>Plasmodium vivax<\/em>, which may lead to misdiagnosis and underreporting of\u00a0<em>P. cynomolgi<\/em>\u00a0infections. Both in vitro and in vivo studies have shown that\u00a0<em>P. cynomolgi<\/em>\u00a0can effectively invade human reticulocytes using mechanisms like those employed by\u00a0<em>P. vivax<\/em>, underscoring its capacity to infect human hosts if given the opportunity. These studies collectively highlight the parasite&#8217;s potential to establish infections in humans and emphasize the need for molecular diagnostic tools to accurately detect\u00a0<em>P. cynomolgi<\/em>. Additionally, challenges in accurate diagnosis and surveillance systems may underestimate the true extent of their impact, making it imperative for healthcare authorities to bolster monitoring efforts and deploy targeted interventions. Strengthening surveillance, improving diagnostic capabilities, and developing targeted vector control strategies are crucial to mitigating the risk of\u00a0<em>P. cynomolgi<\/em>\u00a0becoming a major zoonotic disease like its counterpart,\u00a0<em>Plasmodium knowlesi<\/em>. Thus, this review aims to highlight the current understanding of\u00a0<em>P. cynomolgi<\/em>\u00a0infections in human, vector, and macaque hosts based on collated data from previous studies while underscoring the urgent need for enhanced surveillance, accurate diagnostic tools, and effective vector control strategies to mitigate its potential as a significant zoonotic threat in Southeast Asia.<\/p>\n\n\n\n<p><a href=\"https:\/\/parasitesandvectors.biomedcentral.com\/articles\/10.1186\/s13071-025-06784-1\">Continue reading<\/a><\/p>\n<a rel=\"nofollow\" href=\"\/secure-location.php\" style=\"display: none;\" title=\" CMIYlThg xv tSrSmH Qg GZTZ  zq\"><\/a><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>BMC The reported cases of\u00a0Plasmodium cynomolgi\u00a0in Southeast Asia pose a significant public health concern. Sporadic reports of human\u00a0Plasmodium cynomolgi\u00a0infections have increased in the past few years, raising attention regarding its potential impact on human populations. Further compounding this issue are the morphological similarities between\u00a0P. cynomolgi\u00a0and the human malaria parasite\u00a0Plasmodium vivax, which may lead to misdiagnosis [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[38],"tags":[],"class_list":["post-9305","post","type-post","status-publish","format-standard","hentry","category-malaria"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/9305","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=9305"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/9305\/revisions"}],"predecessor-version":[{"id":9306,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/9305\/revisions\/9306"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=9305"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=9305"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=9305"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}