{"id":9936,"date":"2025-07-23T10:15:54","date_gmt":"2025-07-23T15:15:54","guid":{"rendered":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/?p=9936"},"modified":"2025-07-23T10:15:57","modified_gmt":"2025-07-23T15:15:57","slug":"a-rare-drug-trial-for-long-covid-failed-yielding-lessons-on-study-design","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/2025\/07\/23\/a-rare-drug-trial-for-long-covid-failed-yielding-lessons-on-study-design\/","title":{"rendered":"A rare drug trial for long Covid failed, yielding lessons on study design"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p><a href=\"https:\/\/www.statnews.com\/2025\/07\/22\/long-covid-research-mistakes-to-fix\/\">STAT<\/a> C 007, a German infusion that had lifted hope of patients, is heading for new study. After years with long Covid \u2014 debilitated by fatigue, headaches, and neurological issues \u2014 her symptoms dramatically receded. While not fully back to her pre-Covid-19 baseline, she was able to resume university classes and other daily activities.<\/p>\n\n\n\n<p>\u201cIn the last few months, I have literally regained life,\u201d Bhalla said in an interview last November.<\/p>\n\n\n\n<p>Bhalla posted on social media about her experience, garnering attention from other people with long Covid who hoped they could benefit from the same drug: an infusion called BC 007 (or rovunaptabin). Berlin Cures, the company that developed this drug, had repurposed it from heart disease research, hypothesizing that it could alleviate symptoms by reducing autoantibodies \u2014 immune system components that mistakenly attack the body as if it is an outside invader.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>STAT C 007, a German infusion that had lifted hope of patients, is heading for new study. After years with long Covid \u2014 debilitated by fatigue, headaches, and neurological issues \u2014 her symptoms dramatically receded. While not fully back to her pre-Covid-19 baseline, she was able to resume university classes and other daily activities. \u201cIn [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[11],"tags":[],"class_list":["post-9936","post","type-post","status-publish","format-standard","hentry","category-covid"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/9936","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/comments?post=9936"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/9936\/revisions"}],"predecessor-version":[{"id":9937,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/posts\/9936\/revisions\/9937"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/media?parent=9936"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/categories?post=9936"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/healthsecurity\/transmission\/wp-json\/wp\/v2\/tags?post=9936"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}