Bioinformatics & Systems Biology Faculty

The Bioinformatics & Systems Biology (BISB) doctoral program includes faculty members from the following colleges, departments and institutes: Anesthesiology, Biochemistry and Molecular Biology, Biology (UNO), Cellular and Integrative Physiology, College of Pharmacy, Computer Science (UNO), Eppley Cancer Institute, Genetics Cell Biology and Anatomy, Information Science and Technology (UNO), Interdisciplinary Informatics (UNO), Internal Medicine - DEM, Mathematics (UNO), Munroe-Meyer Institute, Neurological Sciences, Obstetrics and Gynecology, Pathology and Microbiology, Pharmacology and Experimental Neuroscience, Pharmacy Practice and Science, and Surgery.

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Maher Y. Abdalla, PhD
Assistant Professor, Department of Pathology and Microbiology
Research focus:  Reactive Oxygen Species (ROS), Heme Oxygenase-1 (HO-1) and immune cells in pancreatic ductal adenocarcinoma (PDAC) and prostate cancer.


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Hesham Ali, PhD
Dean, Department of Information Science and Technology (UNO)
Research focus:  Developing secure and energy-aware wireless infrastructure to address tracking and monitoring problems in medical environments, particularly to study mobility profiling for various groups and to conduct a population analysis approach to advancing healthcare research.


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Hamid Band

Hamid Band, MD, PhD
Professor, Eppley Cancer Institute
Research focus:  Regulation of receptor signaling by endocytic traffic; Cbl-family and CHIP ubiquitin ligases; EHD-family endocytic recycling regulators; mouse genetic models; cancer and stem cell biology.


Vimla Band

Vimla Band, PhD
Professor and Chair, Department of Genetics, Cell Biology and Anatomy
Research focus:  Delineate molecular mechanisms of early steps in transformation of mammary epithelial cells with the goal of identifying novel molecular diagnostic/prognostic markers and potential therapy targets of breast cancers.


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Kiran Bastola, PhD
Associate Professor, Department of Information Science and Technology (UNO)
Research focus:  Computational biology including gene regulation with noncoding RDA, mining for interesting patterns form genomic sequences for use in molecular diagnostics, public health, secondary metabolism and biology of the mitochondria in disease, as well as extreme environments.


Kishor Bhakat

Kishor K. Bhakat, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy
Research focus:  Mitotic gene bookmarking:  A novel dimension of epigenetic memory in cancer for post-mitotic transcriptional reactivation; APE1 and its acetylation: A potential prognostic and predictive biomarker in cancer.


Jennifer Black

Jennifer Black, PhD
Professor, Eppley Cancer Institute
Research focus:  Colon cancer; endometrial cancer; pancreatic cancer; cell signaling (kinases and phosphatases) cell cycle regulation; control of protein translation in cancer; protein kinase C; PP2A.


Keely Buesing

Keely Buesing, MD, FACS
Associate Professor, Department of Surgery
Research focus:  Large animal and pulmonary cellular investigation of novel therapeutics targeting Acute Respiratory Distress Syndrome (ARDS).


Siddappa Byrareddy

Siddappa Byrareddy, PhD
Associate Professor, Department of Pharmacology & Experimental Neuroscience
Research focus:  Understanding host-virus dynamics using molecular biology, virology, immunology, systems biology, and genomic tools to develop prevention strategies for HIV/AIDS and other infectious diseases, such as Zika virus.


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Scott Campbell

W. Scott Campbell, MBA, PhD
Associate Professor, Department of Pathology and Microbiology
Research focus:  Health informatics and pathology informatics.


Adam Case

Adam J. Case, PhD
Assistant Professor, Department of Cellular & Integrative Physiology
Research focus:  Redox signaling and function of T-lymphocytes during psychological trauma (e.g. PTSD); examining the interplay between the autonomic nervous and immune systems.


Kishore Challagundla

Kishore Challagundla, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology
Research focus:  Role of extra cellular vesicles (EV's) and the non-coding RNAs in affecting immunotherapy response and escaping immune surveillance in pediatric cancers, in particular neuroblastoma and acute myeloid leukemia.


Pi-Wan Cheng

Pi-Wan Cheng, PhD
Professor, Department of Biochemistry and Molecular Biology
Research focus:  Mechanism of altered glycosylation in cancer development/progression and alcohol abuse, and development of altered glycans-based markers for identification and targeted therapy of advanced cancers.


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Xiaoyue Cheng, PhD
Assistant Professor, Department of Mathematics (UNO)
Research focus:  Data visualization and interactive graphics, data exploratory analysis, data mining, statistical classification.


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Parvathi Chundi, PhD
Professor, Department of Computer Science (UNO)
Research focus:  Machine learning algorithms for unstructured data collections; serious games; Big Data Frameworks.


Pawel Ciborowski

Pawel Ciborowski, PhD
Professor and Director of Mass Spectometry and Proteomics Core Facility, Department of Pharmacology and Experimental Neuroscience
Research focus:  Protein structure and functions; proteomics.


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Kate Cooper (Dempsey), PhD
Assistant Professor, College of Information Science & Technology (UNO)
Research focus:  Biomedical "big" data, dynamic network modeling and analysis, precision wellness, public health informatics.


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John Davis

John S. Davis, PhD
Professor, Director of Research and Development - Olson Center for Women's Health, Department of Obstetrics and Gynecology
Research focus:  Reproductive endocrinology and oncology.


Paul Davis

Paul Davis, PhD
Associate Professor, Department of Biology (UNO)
Research focus:  Investigating and developing novel approaches to prevent and treat human parasitic infections, using approaches that include molecular biology, bioinformatics, -omics, high-content imaging, and genetics.


Andrew Dudley

Andrew Dudley, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy
Research focus:  Mechanisms that regulate the development and homeostasis of musculoskeletal tissue using methods from embryology, molecular biology, cell biology, genetics and tissue engineering, with the goal of generating novel therapies for regenerative medicine.


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Howard Fox

Howard S. Fox, MD, PhD
Professor, Department of Neurological Sciences
Research focus:  Neurodegeneration, brain dysfunction and viral infections of the brain.


Ann Fruhling, PhD

Ann Fruhling, PhD
Professor, College of Information Science and Technology (UNO)
Research focus:  User interface design and evaluation; usability studies; information systems design strategies for medical emergency response systems, e-health applications; health informatics; agile system development; implementation and management strategies.


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Lie Gao

Lie Gao, MD, PhD
Assistant Professor, Department of Cellular and Integrative Physiology
Research focus:  Neural control of circulation and autonomic function; pancreatic islet function and diabetes; skeletal muscle function and exercise intolerance in heart function.


Howard Gendelman

Howard E. Gendelman, MD
Professor, Department of Pharmacology and Experimental Neuroscience
Research focus:  Investigate Th1 and Th2 cell responses in Parkinson's disease; study the role of mononuclear phagocytes in neurotoxicity and neuroregeneration in HIV dementia.


Dario Ghersi, PhD

Dario Ghersi, PhD
Assistant Professor, College of Information Science and Technology (UNO)
Research focus:  Large-scale cancer genomics datasets, integrating different types of data (including protein structure) to gain insight into the molecular bases of cancer and immune system function.


Gargi Ghosal

Gargi Ghosal, PhD
Assistant Professor, Department of Genetics, Cell Biology and Anatomy
Research focus:  Understand the basic science underlying replication stress response in cancer and aging; identify new targets and bio-markers for cancer therapies and facilitate the development of strategies to overcome drug resistance and improve cancer therapies.


Karen Gould

Karen Gould, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy
Research focus:  Estrogen receptor alpha regulation of lupus; identification of the Mom5 modifier of intestinal tumorigenesis.


Babu Guda

Chittibabu (Babu) Guda, PhD
Professor, Department of Genetics, Cell Biology and Anatomy
Research focus:  Development and application of computational methods for genomic data analyses including cancer genomics, functional annotation of proteins, pathways, networks and systems in biomedical research.


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Tony Hollingsworth

Michael A. (Tony) Hollingsworth, PhD
Professor, Eppley Cancer Institute
Research focus:  Basic and translational research in pancreatic cancer, including investigation of the biology of tumor progression, discovery and validation of biomarkers of early detection and disease progression, development and testing of novel therapeutics, including targeted therapies and immunotherapies.


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Adam Karpf

Adam R. Karpf, PhD
Professor, Eppley Cancer Institute
Research focus:  Ovarian cancer biology and therapeutics; Cancer epigenetics.


Tammy Kielian

Tammy L. Kielian, PhD
Professor, Department of Pathology and Microbiology
Research focus:  Host-pathogen interactions, immunology, neuroimmunology, tranlational therapeutics.


David Klinkebiel

David Klinkebiel, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology
Research focus:  Dynamics associated with changes in the genome and epigenome of human disease.


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Marilynn Larson

Marilynn Larson, PhD
Assistant Professor, Department of Pathology and Microbiology
Research focus:  Development of diagnostics and therapeutics for pathogen identification and treatment; respectively; determining the molecular mechanisms that allow pathogens to replicate and persist.


Ming-Fong Lin

Ming-Fong Lin, PhD
Professor, Department of Biochemistry and Molecular Biology
Research focus:  Mechanism of cell growth regulation by steroids via cross-talk of ROS and tyrosine phosphorylation signaling.


Merry Lindsey, PHD

Merry Lindsey, PhD
Chair and Professor, Department of Cellular and Integrative Physiology
Research focus:  Identifying novel MMP substrates in post-MI tissues using omics strategies to identify novel extracellular matrix signaling pathways altered post-MI; examining the roles of macrophages and fibroblasts in post-MI remodeling of the left ventricle; discovering novel biomarkers of adverse left ventricular remodeling.


Guoqing Lu, PhD

Guoqing Lu, PhD
Professor, Department of Biology & Interdisciplinary Informatics (UNO).
Research focus:  Theoretical and applied bioinformatics, with a focus on comparative genomics and evolutionary informatics.


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Mahbubul Majumder, PhD

Mahbubul Majumder, PhD
Associate Professor, Department of Mathematics (UNO)
Research focus:  Exploratory data analysis; data visualization and visual inference; statistical modeling; data science.


Luis Marky

Luis Marky, PhD
Professor, College of Pharmacy
Research focus:  Biophysical chemistry and molecular forces that control the conformational stability and flexibility of nucleic acids, including Okazaki fragments, hairpin loops, intramolecular triplexes, G-quadruplexes, C-quadruplexes, and three- & four-arm DNA junctions and their interaction with drugs.


Karoly Mirnics

Karoly Mirnics, MD, PhD
Director, Munroe-Meyer Institute
Research focus:  Animal models of neurodevelopmental and psychiatric disorders; effects of Gene-Environmental-Drug interactions on the developing brain; role of disrupted cholesterol biosynthesis of brain function - all using genetic, molecular, cellular and biochemical tools in our studies, coupled with drug screening and mouse behavioral assessments.


Paras Kumar Mishra

Paras Kumar Mishra, PhD
Associate Professor, Department of Cellular and Integrative Physiology
Research focus:  MicroRNomics of cardiovascular diseases and diabetic cardiomyopathy.


DJ Murry

DJ Murry, PharmD
Associate Professor, Department of Pharmacy Practice and Science
Research focus:  Ways to individualize drug therapy using pharmacokinetic and pharmacogenomics information; from in vitro metabolism and transport studies, animal pharmacokinetic studies, to clinical studies evaluating drug therapy in patients.


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Caroline Ng

Caroline Ng, PhD
Assistant Professor, Department of Pathology & Microbiology
Research focus:  Biology and pathogenesis of Plasmodium falciparum, genetic and molecular mechanisms underlying drug resistance.


Robert Norgren

Robert B. Norgren, PhD
Professor, Department of Genetics, Cell Biology and Anatomy
Research focus:  Use of nonhuman primate genomics to better understand human genetic disease.


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Scot Ouellette

Scot Ouellette, PhD
Associate Professor, Department of Pathology & Microbiology
Research focus:  Chlamydial microbiology: bacterial cell division, gene regulation, host-pathogen interactions.


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Babu Padanilam

Babu Padanilam, PhD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Cellular, biochemical and molecular analysis of the pathophysiology of acute ischemic renal injury and chronic kidney disease.


Gurudutt Pendyala

Gurudutt N. Pendyala, PhD
Associate Professor, Department of Anesthesiology
Research focus:  Animal models of addiction, sex differences in drug abuse; Synaptic biology; Epigenetic regulation, role of microRNAs at the synapse in drug addication, mechanisms and role in gene regulation; Prenatal drug exposure and synaptic development; Integrative Systems Biology approach to understand synaptic aberrations in chronic drug abuse; High input technologies-genomics, mass spectrometry-based proteomics and metabolomics.


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Matthew Rizzino

Matthew Rizzo, MD, FAAN
Professor, Department of Neurological Sciences
Research focus:  Memory disorders; behavioral consequences of aging and neurological disorders.


Jim Rogers, PHD

Jim Rogers, PhD
Associate Professor, Department of Mathematics (UNO)
Research focus:  Mathematical biology.


Jordan Rowley, PhD

Jordan Rowley, PhD
Assistant Professor, Department of Genetics, Cell Biology & Anatomy
Research focus:  3D organization of DNA within the nucleus.


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Pankaj Singh

Pankaj Singh, PhD
Professor, Eppley Cancer Institute
Research focus:  Cancer metabolism, immuno-metabolism, signal transduction in cancer, tumor-microenvironment interactions, therapy resistance, metastasis, cancer cachexia, personalized cancer medicine, and multi-omics systems biology.


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William Tapprich, PhD
Professor, Department of Biology (UNO)
Research focus:  Understanding the structure and function of viral RNA molecules, particularly enteroviral genomic RNA.


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Saraswathi Viswanathan

Saraswathi Viswanathan, PhD
Assistant Professor, Department of Internal Medicine - Diabetes, Endocrine and Metabolism
Research focus:  Determine the link between obesity and cardiovascular disease.


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Hanjun Wang

Hanjun Wang, MD
Associate Professor, Department of Cellular and Integrative Physiology
Research focus:  Cardiovascular reflexes during exercise; neural control mechanisms underlying the exaggerated cardiovascular response and hyperventilation during exercise in the chronic heart failure state.


David Warren

David Warren, PhD
Assistant Professor, Department of Neurological Sciences
Research focus:  Cognitive neuroscience investigations of cognition (especially memory) and related brain networks that combine neuroimaging, neuropsychological, and neurostimulation methods.


Tony Wilson

Tony W. Wilson, PhD
Associate Professor, Department of Neurological Sciences
Research focus:  Human neurophysiology and imaging in cognitive aging, healthy development, neurodegenerative diseases, and drug abuse.


Nicholas Woods

Nicholas Woods, PhD
Assistant Professor, Eppley Cancer Institute
Research focus:  Systems biology based analysis of cancer signaling pathways.


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