Faculty

Integrative Physiology and Molecular Medicine Faculty

The Integrative Physiology and Molecular Medicine (IPMM) doctoral program includes faculty members from the following colleges, departments and institutes: Biochemistry and Molecular Biology, Cellular and Integrative Physiology, College of Dentistry, College of Nursing, College of Pharmacy, College of Public Health, Emergency Medicine, Eppley Institute, Genetics Cell Biology and Anatomy, six Internal Medicine departments, Munroe-Meyer Institute, Obstetrics and Gynecology, Ophthalmology and Visual Sciences, Pathology and Microbiology, three Pediatric departments, Pharmacology and Experimental Neuroscience, Radiology and Surgery.

A      B    C      D      E      F      G      H      I      J      K      L      M      N      O      P      Q      R      S      T     U      V     W     X      Y     Z

 

Daniel Anderson Daniel R. Anderson, MD, PhD
Associate Professor, Department of Internal Medicine - Cardiology
Research focus:  Molecular and cellular immunology; innate immunity (preexisting immunity) and how such immune responses contribute to the mechanisms of cardiovascular disease processes, specifically focused on underlying mechanisms of viral myocarditis, atherosclerotic disease and the impact inflammation has on cardiac rhythm abnormalities.

Ann Anderson Berry Ann Anderson Berry, MD, PhD
Professor, Department of Pediatrics - Neonatology
Research focus:  Nutrition of the ELBW infant, preterm infant protein requirements, human milk fortification, Vitamin D metabolism in the mother infant dyad, Vitamin A deficiency, Vitamin E metabolism.

Return To Top


Tim Baxter B. Timothy Baxter, MD, FACS
Professor, Department of Surgery
Research focus:  Use of doxycycline to slow or stop the growth of aneurysms.

Robert Bennett Robert Bennett, PhD
Professor, Department of Internal Medicine - Diabetes, Endocrinology and Metabolism (DEM)
Research focus:  Antifibrotic effects of the hormone relaxin and related peptides; expression and signaling of relaxin receptors; internalization and degradation of relaxin, insulin and related hormones; the role of relaxin in adipose function.

Keshore Bidasee Keshore Bidasee, PhD
Associate Professor, Department of Pharmacology and Experimental Neuroscience
Research focus:  Molecular and cellular mechanisms responsible for cardiovascular complication in individuals with diabetes mellitus (DM), and identify therapeutic strategies that could be used to slow their progression.

Erkia Boesen Erika I. Boesen, PhD
Associate Professor, Department of Cellular and Integrative Physiology
Research focus:  Iron-medicated kidney damage in lupus nephritis; renal control of salt and water homeostasis.

Stephen Bonasera Stephen Bonasera, MD, PhD
Associate Professor, Department of Internal Medicine -  Geriatrics
Research focus:  Age related changes in brain function.

Keely Buesing Keely Buesing, MD, FACS
Associate Professor, Department of Surgery
Research focus:  Large animal and pulmonary cellular investigation of novel therapeutics targeting Acute Respiratory Distress Syndrom (ARDS).

Return To Top


Mark Carlson Mark Carlson, MD, FACS
Professor, Department of Surgery
Research focus:  Cancer; regenerative medicine; hemostasis; wound healing.

Pam Carmines Pamela K. Carmines, PhD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Renal microcirculation, vasoactive agents and intracellular signaling events regulating renal arteriolar tone, diabetes mellitus.

Adam Case Adam J. Case, PhD
Assistant Professor, Department of Cellular & Integrative Physiology
Research focus:  Redox signaling and function of T-lymphocytes during psychological trauma (e.g. PTSD); examining the interplay between the autonomic nervous and immune systems.

Claudia Chaperon Claudia Chaperon, PhD, RN, APRN-NP, BC
Associate Professor, College of Nursing
Research focus:  Effects of sleep-disturbing environments on late life health maintenance: water and electrolyte balance and blood pressure regulation; effects of sleep deprivation during the perimenopause in female mice; neurotrophin gene regulation of rhythms.

Yiannis Chatzizisis

Yiannis S. Chatzizisis, MD, PhD
Associate Professor, Internal Medicine - Cardiology
Research focus:  Vascular biology of atherosclerosis; cardiovascular biomechanics; mechanobiology; computational stent simulations; renal denervation.


Return To Top


John Davis John S. Davis, PhD
Professor, Director of Research and Development - Olson Center for Women's Health, Department of Obstetrics and Gynecology
Research focus:  Reproductive endocrinology and oncology.

Cyrus Desouza Cyrus Desouza, MBBS
Professor, Department of Internal Medicine – Diabetes, Endocrinology and Metabolism (DEM)
Research focus:  Improving outcomes in diabetes and obesity patients using treatment algorithms; mechanisms of diabetes and metabolic syndrome on vascular and brain function.

Andrew Dudley Andrew Dudley, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy
Research focus:  Mechanisms that regulate the development and homeostasis of musculoskeletal tissue using methods from embryology, molecular biology, cell biology, genetics and tissue engineering, with the goal of generating novel therapies for regenerative medicine.

Return To Top


Lie Gao Lie Gao, MD, PhD
Assistant Professor, Department of Cellular and Integrative Physiology
Research focus:  Neural control of circulation and autonomic function; pancreatic islet function and diabetes; skeletal muscle function and exercise intolerance in heart function.

Karen Gould Karen Gould, PhD
Associate Professor, Department of Genetics, Cell Biology and Anatomy
Research focus:  Estrogen receptor alpha regulation of lupus; identification of the Mom5 modifier of intestinal tumorigenesis.

Rebekah Gundry, PhD Rebekah Gundry, PhD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Development and application innovative mass spectrometry (MS) technologies, bioinformatics tools, and methodologies to transform our understanding of cell surface proteins and glycans, and answer outstanding questions in stem cell biology and cardiac pathology.

Return To Top


Frederick Hamel Frederick G. Hamel, PhD
Professor, Department of Internal Medicine - Diabetes, Endocrinology and Metabolism (DEM)
Research focus:  Degradation of insulin and its relationship to insulins mechanism of action; polypeptide hormone metabolism; diabetes mellitus.

Curtis Hartman Curtis Hartman, MD
Associate Professor, Department of Orthopedic Surgery and Rehabilitation
Research focus:  Management of infected hip and knee replacements.

Return To Top


Peter Kador Peter Kador, PhD
Professor, College of Pharmacy
Research focus:  Design and synthesis of multifunctional antioxidants and enzyme inhibitors; the mechanism of action drugs and development of agents as they relate to the inhibition of diabetic complications; age related macular degeneration, cataract development and neurodegeneration, including Alzheimer’s disease; basic cellular mechanisms that lead to the initiation of diabetic complications and the development of disease-associated animal models.

Kusum Kharbanda Kusum Kharbanda, PhD
Professor, Department of Internal Medicine - Gastroenterology and Hepatology
Research focus:  alcohol liver injury with emphasis on alcohol's deleterious effect in altering the methionine metabolic pathway and lowering the ratio of the methyl dontor, SAM, to its product, SAH.

Return To Top


Robert Lewis Robert Lewis, PhD
Professor, Eppley Cancer Institute
Research focus:  Identification and targeting of Ras-driven, tumor-specific pathways; molecular mechanisms controlling cellular and organismal energy balance.

Yulong Li Yulong Li, MD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Dysfunction of baroreceptor neurons in heart failure and diabetes: cellular and molecular mechanisms.

Merry Lindsey, PhD Merry Lindsey, PhD
Chair and Professor, Department of Cellular and Integrative Physiology
Research focus:  Identifying novel MMP stustrates in post-MI tissues using omics strategies to identify novel extracellular matrix signaling pathways altered post-MI; examining the roles of macrophages and fibroblasts in post-MI remodeling of the left ventricle; discovering novel biomarkers of adverse left ventricular remodeling.

Steven Lisco

Steven Lisco, MD
Professor, Department of Anesthesiology
Research focus:  Critical Care Management, thoracic and vascular anesthesiology, management of complex airways, blood management.


Brian Lowes Brian Lowes, MD, PhD
Professor, Department of Internal Medicine - Cardiology
Research focus:  Novel education clinical trainees and education program with a goal to develop clinicians and scientists in sub-Saharan Africa.

Richard Lutz Richard Lutz, MD
Associate Professor, Munroe-Meyer Institute
Research focus:  Birth defects; mental retardation; autism; enzyme replacement therapy; pediatric growth problems.

Return To Top


David McMillan David McMillan, PhD
Professor, Department of Pharmacology and Experimental Neuroscience
Research focus:  Mechanisms of toxicity of drugs and environmental chemicals; mechanism underlying pro-oxidant drug-induced hemolytic anemia , and in the metabolism and toxicity of the environmental contaminant, trichloroethylene.

Paras Kumar Mishra Paras Kumar Mishra, PhD
Associate Professor, Department of Cellular and Integrative Physiology
Research focus:  MicroRNomics of cardiovascular diseases and diabetic cardiomyopathy.

Dan Monaghan Daniel T. Monaghan, PhD
Professor, Department of Pharmacology and Experimental Neuroscience
Research focus:  Development of drugs for modulating NMDA receptor activity for treating schizophrenia and autism.

Lee Mosley R. Lee Mosley, PhD
Professor, Department of Pharmacology and Experimental Neuroscience
Research focus:  Regulation of T Lymphocyte function; T cell-mediated immunity in neurodegenerative disorders.

Return To Top


Robert Norgren Robert B. Norgren, PhD
Professor, Department of Genetics, Cell Biology and Anatomy
Research focus:  Use of nonhuman primate genomics to better understand human genetic disease.

Return To Top


Babu Padanilam Babu Padanilam, PhD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Cellular, biochemical and molecular analysis of the pathophysiology of acute ischemic renal injury and chronic kidney disease.

Kaushik Patel Kaushik P. Patel, PhD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Neural control of circulation; neural regulation of cardiovascular and renal function in health and disease states.

Gurudutt Pendyala, PhD Gurudutt N. Pendyala, PhD
Associate Professor, Department of Anesthesiology
Research focus:  Animal models of addiction, sex differences in drug abuse; Synaptic biology; Epigenetic regulation, role of microRNAs at the synapse in drug addication, mechanisms and role in gene regulation; Prenatal drug exposure and synaptic development; Integrative Systems Biology approach to understand synaptic aberrations in chronic drug abuse; High input technologies-genomics, mass spectrometry-based proteomics and metabolomics.

Armen Petrosyan Armen Petrosyan, MD, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology
Research focus:  Mechanism of Golgi alteration in advanced prostate cancer: focus on aberrant glycosylation; role for non-muscle Myosin IIA in alcohol-induced Golgi fragmentation.

Iraklis Pipinos Iraklis Pipinos, MD, PhD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Development of regenerative medicine strategies for skeletal muscle tissues in the legs of patients suffering from peripheral arterial disease (PAD).

Thomas Porter

Thomas Porter, MD
Chair and Professor, Department of Internal Medicine - Cardiology
Research focus:  Targeted blood brain barrier permeability changes with ultrasound and microbubbles.


Bunny Pozehl Bunny Pozehl, PhD, RN, APRN-NP, FAHA, FAAN
Professor, College of Nursing
Research focus:  Exercise training interventions and promoting adherence to exercise in hear t failure.

Sundaralingam Premaraj Sundaralingam Premaraj, BDS, MS, PhD, FRCD(C)
Associate Professor, College of Dentistry
Research focus:  Cranial suture biology; (TGF) ß cell signaling in osteoblasts; molecular biology of tooth movement.

Return To Top


Stephen Rennard

Stephen I. Rennard, MD
Professor, Department of Internal Medicine - Pulmonary, Critical Care, Sleep and Allergy
Research focus:  Cellular mechanisms that underlie altered tissue structure in lung disease, particularly with regard to chronic obstructive pulmonary disease (COPD).


William Rizzo William Rizzo, MD
Professor, Department of Pediatrics
Research focus:  Sjogren-Larsson Syndrome and other inherited metabolic diseases.

Debra Romberger Debra Romberger, MD
Professor, Department of Internal Medicine
Research focus:  Agricultural/occupation/environmental lung disease; airway epithelial repair and injury mechanisms; clinical problems associated with COPD; mycobacterial lung disease.

Shyamal Roy Shyamal K. Roy, PhD
Professor, Department of Obstetrics & Gynecology and Cellular & Integrative Physiology
Research focus:  Endocrine regulation of follicular development, growth factors, signal transduction in ovarian cells and biochemistry of granulosa cells.

Return To Top


Steve Sansom Steven C. Sansom, PhD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Physiological mechanisms of ion transport in the kidney.

Schiller_Alicia.jpg Alicia Schiller, PhD
Assistant Professor, Department of Anesthesiology
Research focus:  Quantification of sympathetic nervous system output and vascular control for clinically relevant applications, including intraprocedural feedback for renal denervation, hemorrhage, and as a screening tool for the presence of dysautonomia.

Harold Schultz

Harold D. Schultz, PhD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Sensory and motor functions of the autonomic nervous system.


Joseph Sisson Joseph Sisson, MD
Professor, Department of Internal Medicine
Research focus:  Control of ciliary motility; regulation of ciliary beating in primary cultures of ciliated tracheal epithelium; ethanol as a model agonist and the mechanism(s) by which ethanol desensitizes the ciliary apparatus to subsequent stimulation by physiologic agonists; kinase phosphorylation targets in the cilia axoneme to determine the mechanism(s) by which phosphorylation activates dyneins and other motor elements of the axoneme.

Return To Top


Geoffrey Thiele Geoffrey M. Thiele, PhD
Professor, Department of Internal Medicine - Rheumatology
Research focus:  Autoimmunity, immune system disorders, immunopathology; infectious diseases/agents; Rheumatoid arthritis, atherosclerosis, breast cancer and the immune system, bone loss and erosion, alcoholic liver disease.

Wallace Thoreson Wallace B. Thoreson, PhD
Professor, Department of Ophthalmology and Visual Sciences
Research focus:  Visual information processing by the retina; electrophysiology and optical imaging techniques to study transmission at ribbon synapses of rod and cone photoreceptors.

Myron Toews Myron L. Toews, PhD
Professor, Department of Pharmacology and Experimental Neuroscience
Research focus:  Regulation of G protein-coupled receptors and their signaling pathways; lysophosphatidic acid and its receptors in lung disease; epidermal growth factor receptors and protease signaling in agricultural dust-induced lung disease, oxytocin receptors and signaling in primate social behavior.

Return To Top


Matthew Van Hook Matthew Van Hook, PhD
Assistant Professor, Department of Ophthalmology and Visual Sciences
Research focus:  Influence of neurodegenerative disease of the visual system (i.e. glaucoma) on the function of neurons and synapses i the brain and retina.

Joseph Vetro Joseph Vetro, PhD
Assistant Professor, College of Pharmacy
Research focus:  Developing novel synthetic targeted drug and gene delivery nanocarriers for the anti-angiogenesis treatment of cancer; improving development paradigms for targeted bioimaging and drug delivery nanocarriers; developing subunit vaccines based on the novel adjuvant, EP67.

Saraswathi Viswanathan Saraswathi Viswanathan, PhD
Assistant Professor, Department of Internal Medicine - Diabetes, Endocrine and Metabolism
Research focus:  Determine the role of obesity in modulating the pathogenesis of insulin resistance, alcohol-associated liver injury, and pancreatic cancer.

Return To Top


Hanjun Wang Hanjun Wang, PhD
Associate Professor, Department of Cellular and Integrative Physiology
Research focus:  Cardiovascular reflexes during exercise; neural control mechanisms underlying the exaggerated cardiovascular response and hyperventilation during exercise in the chronic heart failure state.

Return To Top


Sowmya Yelamanchili, PhD Sowmya Yelamanchili, PhD
Assistant Professor, Department of Anesthesiology
Research focus:  MicroRNAs in neurodegenerative disease, HIV, Parkinson's Disease.

Return To Top


Chi (Kevin) Zhang

Chi (Kevin) Zhang, MD, PhD
Associate Professor, Department of Radiation Oncology
Research focus:  Development of novel strategies for delivery of therapies to brain tumors.


Matthew Zimmerman Matthew C. Zimmerman, PhD
Associate Professor, Department of Cellular and Integrative Physiology
Research focus:  Role of reactive oxygen species and redox signaling in the brain in the pathogenesis of cardiovascular disease; utilization of nanoformulated antioxidants for the improved treatment of cardiovascular disease.

Irving Zucker Irving H. Zucker, PhD
Professor, Department of Cellular and Integrative Physiology
Research focus:  Neural control of cardiovascular function; heart failure; hypertension; sympathetic function.

Return To Top