Integrative Physiology and Molecular Medicine Faculty
The Integrative Physiology and Molecular Medicine (IPMM) doctoral program includes faculty members from the following colleges, departments and institutes: Biochemistry and Molecular Biology, Cellular and Integrative Physiology, College of Dentistry, College of Nursing, College of Pharmacy, College of Public Health, Emergency Medicine, Eppley Institute, Genetics Cell Biology and Anatomy, six Internal Medicine departments, Munroe-Meyer Institute, Obstetrics and Gynecology, Ophthalmology and Visual Sciences, Pathology and Microbiology, three Pediatric departments, Pharmacology and Experimental Neuroscience, Radiology and Surgery.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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Daniel R. Anderson, MD, PhD Associate Professor, Department of Internal Medicine - Cardiology Research focus: Molecular and cellular immunology; innate immunity (preexisting immunity) and how such immune responses contribute to the mechanisms of cardiovascular disease processes, specifically focused on underlying mechanisms of viral myocarditis, atherosclerotic disease and the impact inflammation has on cardiac rhythm abnormalities. |
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Ann Anderson Berry, MD, PhD Professor, Department of Pediatrics - Neonatology Research focus: Nutrition of the ELBW infant, preterm infant protein requirements, human milk fortification, Vitamin D metabolism in the mother infant dyad, Vitamin A deficiency, Vitamin E metabolism. |
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B. Timothy Baxter, MD, FACS Professor, Department of Surgery Research focus: Use of doxycycline to slow or stop the growth of aneurysms. |
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Robert Bennett, PhD Professor, Department of Internal Medicine - Diabetes, Endocrinology and Metabolism (DEM) Research focus: Antifibrotic effects of the hormone relaxin and related peptides; expression and signaling of relaxin receptors; internalization and degradation of relaxin, insulin and related hormones; the role of relaxin in adipose function. |
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Keshore Bidasee, PhD Associate Professor, Department of Pharmacology and Experimental Neuroscience Research focus: Molecular and cellular mechanisms responsible for cardiovascular complication in individuals with diabetes mellitus (DM), and identify therapeutic strategies that could be used to slow their progression. |
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Erika I. Boesen, PhD Associate Professor, Department of Cellular and Integrative Physiology Research focus: Iron-medicated kidney damage in lupus nephritis; renal control of salt and water homeostasis. |
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Stephen Bonasera, MD, PhD Associate Professor, Department of Internal Medicine - Geriatrics Research focus: Age related changes in brain function. |
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Keely Buesing, MD, FACS Associate Professor, Department of Surgery Research focus: Large animal and pulmonary cellular investigation of novel therapeutics targeting Acute Respiratory Distress Syndrome (ARDS). |
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Mark Carlson, MD, FACS Professor, Department of Surgery Research focus: Cancer; regenerative medicine; hemostasis; wound healing. |
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Pamela K. Carmines, PhD Professor, Department of Cellular and Integrative Physiology Research focus: Renal microcirculation, vasoactive agents and intracellular signaling events regulating renal arteriolar tone, diabetes mellitus. |
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Claudia Chaperon, PhD, RN, APRN-NP, BC Associate Professor, College of Nursing Research focus: Effects of sleep-disturbing environments on late life health maintenance: water and electrolyte balance and blood pressure regulation; effects of sleep deprivation during the perimenopause in female mice; neurotrophin gene regulation of rhythms. |
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Yiannis S. Chatzizisis, MD, PhD |
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John S. Davis, PhD Professor, Director of Research and Development - Olson Center for Women's Health, Department of Obstetrics and Gynecology Research focus: Reproductive endocrinology and oncology. |
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Cyrus Desouza, MBBS Professor, Department of Internal Medicine – Diabetes, Endocrinology and Metabolism (DEM) Research focus: Improving outcomes in diabetes and obesity patients using treatment algorithms; mechanisms of diabetes and metabolic syndrome on vascular and brain function. |
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Andrew Dudley, PhD Associate Professor, Department of Genetics, Cell Biology and Anatomy Research focus: Mechanisms that regulate the development and homeostasis of musculoskeletal tissue using methods from embryology, molecular biology, cell biology, genetics and tissue engineering, with the goal of generating novel therapies for regenerative medicine. |
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Lie Gao, MD, PhD Assistant Professor, Department of Cellular and Integrative Physiology Research focus: Neural control of circulation and autonomic function; pancreatic islet function and diabetes; skeletal muscle function and exercise intolerance in heart function. |
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Karen Gould, PhD Professor, Department of Genetics, Cell Biology and Anatomy Research focus: Estrogen receptor alpha regulation of lupus; identification of the Mom5 modifier of intestinal tumorigenesis. |
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Rebekah Gundry, PhD Professor, Department of Cellular and Integrative Physiology Research focus: Development and application innovative mass spectrometry (MS) technologies, bioinformatics tools, and methodologies to transform our understanding of cell surface proteins and glycans, and answer outstanding questions in stem cell biology and cardiac pathology. |
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Frederick G. Hamel, PhD Professor, Department of Internal Medicine - Diabetes, Endocrinology and Metabolism (DEM) Research focus: Degradation of insulin and its relationship to insulins mechanism of action; polypeptide hormone metabolism; diabetes mellitus. |
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Curtis Hartman, MD Associate Professor, Department of Orthopedic Surgery and Rehabilitation Research focus: Management of infected hip and knee replacements. |
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Peter Kador, PhD Professor, College of Pharmacy Research focus: Design and synthesis of multifunctional antioxidants and enzyme inhibitors; the mechanism of action drugs and development of agents as they relate to the inhibition of diabetic complications; age related macular degeneration, cataract development and neurodegeneration, including Alzheimer’s disease; basic cellular mechanisms that lead to the initiation of diabetic complications and the development of disease-associated animal models. |
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Kusum Kharbanda, PhD Professor, Department of Internal Medicine - Gastroenterology and Hepatology Research focus: alcohol liver injury with emphasis on alcohol's deleterious effect in altering the methionine metabolic pathway and lowering the ratio of the methyl donor, SAM, to its product, SAH. |
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Robert Lewis, PhD Professor, Eppley Cancer Institute Research focus: Identification and targeting of Ras-driven, tumor-specific pathways; molecular mechanisms controlling cellular and organismal energy balance. |
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Yulong Li, MD Professor, Department of Cellular and Integrative Physiology Research focus: Dysfunction of baroreceptor neurons in heart failure and diabetes: cellular and molecular mechanisms. |
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Merry Lindsey, PhD Chair and Professor, Department of Cellular and Integrative Physiology Research focus: Identifying novel MMP substrates in post-MI tissues using omics strategies to identify novel extracellular matrix signaling pathways altered post-MI; examining the roles of macrophages and fibroblasts in post-MI remodeling of the left ventricle; discovering novel biomarkers of adverse left ventricular remodeling. |
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Steven Lisco, MD |
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Brian Lowes, MD, PhD Professor, Department of Internal Medicine - Cardiology Research focus: Novel education clinical trainees and education program with a goal to develop clinicians and scientists in sub-Saharan Africa. |
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David McMillan, PhD Professor, Department of Pharmacology and Experimental Neuroscience Research focus: Mechanisms of toxicity of drugs and environmental chemicals; mechanism underlying pro-oxidant drug-induced hemolytic anemia , and in the metabolism and toxicity of the environmental contaminant, trichloroethylene. |
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Paras Kumar Mishra, PhD Associate Professor, Department of Cellular and Integrative Physiology Research focus: MicroRNomics of cardiovascular diseases and diabetic cardiomyopathy. |
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Daniel T. Monaghan, PhD Professor, Department of Pharmacology and Experimental Neuroscience Research focus: Development of drugs for modulating NMDA receptor activity for treating schizophrenia and autism. |
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R. Lee Mosley, PhD Professor, Department of Pharmacology and Experimental Neuroscience Research focus: Regulation of T Lymphocyte function; T cell-mediated immunity in neurodegenerative disorders. |
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Robert B. Norgren, PhD Professor, Department of Genetics, Cell Biology and Anatomy Research focus: Use of nonhuman primate genomics to better understand human genetic disease. |
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Kaushik P. Patel, PhD Professor, Department of Cellular and Integrative Physiology Research focus: Neural control of circulation; neural regulation of cardiovascular and renal function in health and disease states. |
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Gurudutt N. Pendyala, PhD Associate Professor, Department of Anesthesiology Research focus: Animal models of addiction, sex differences in drug abuse; Synaptic biology; Epigenetic regulation, role of microRNAs at the synapse in drug addiction, mechanisms and role in gene regulation; Prenatal drug exposure and synaptic development; Integrative Systems Biology approach to understand synaptic aberrations in chronic drug abuse; High input technologies-genomics, mass spectrometry-based proteomics and metabolomics. |
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Armen Petrosyan, MD, PhD Assistant Professor, Department of Biochemistry and Molecular Biology Research focus: Mechanism of Golgi alteration in advanced prostate cancer: focus on aberrant glycosylation; role for non-muscle Myosin IIA in alcohol-induced Golgi fragmentation. |
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Iraklis Pipinos, MD, PhD Professor, Department of Cellular and Integrative Physiology Research focus: Development of regenerative medicine strategies for skeletal muscle tissues in the legs of patients suffering from peripheral arterial disease (PAD). |
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Thomas Porter, MD |
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Bunny Pozehl, PhD, RN, APRN-NP, FAHA, FAAN Professor, College of Nursing Research focus: Exercise training interventions and promoting adherence to exercise in hear t failure. |
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Sundaralingam Premaraj, BDS, MS, PhD, FRCD(C) Associate Professor, College of Dentistry Research focus: Cranial suture biology; (TGF) ß cell signaling in osteoblasts; molecular biology of tooth movement. |
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Stephen I. Rennard, MD |
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William Rizzo, MD Professor, Department of Pediatrics Research focus: Sjogren-Larsson Syndrome and other inherited metabolic diseases. |
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Debra Romberger, MD Professor, Department of Internal Medicine Research focus: Agricultural/occupation/environmental lung disease; airway epithelial repair and injury mechanisms; clinical problems associated with COPD; mycobacterial lung disease. |
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Shyamal K. Roy, PhD Professor, Department of Obstetrics & Gynecology and Cellular & Integrative Physiology Research focus: Endocrine regulation of follicular development, growth factors, signal transduction in ovarian cells and biochemistry of granulosa cells. |
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Steven C. Sansom, PhD Professor, Department of Cellular and Integrative Physiology Research focus: Physiological mechanisms of ion transport in the kidney. |
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Alicia Schiller, PhD Assistant Professor, Department of Anesthesiology Research focus: Quantification of sympathetic nervous system output and vascular control for clinically relevant applications, including intraprocedural feedback for renal denervation, hemorrhage, and as a screening tool for the presence of dysautonomia. |
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Harold D. Schultz, PhD |
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Joseph Sisson, MD Professor, Department of Internal Medicine Research focus: Control of ciliary motility; regulation of ciliary beating in primary cultures of ciliated tracheal epithelium; ethanol as a model agonist and the mechanism(s) by which ethanol desensitizes the ciliary apparatus to subsequent stimulation by physiologic agonists; kinase phosphorylation targets in the cilia axoneme to determine the mechanism(s) by which phosphorylation activates dyneins and other motor elements of the axoneme. |
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Geoffrey M. Thiele, PhD Professor, Department of Internal Medicine - Rheumatology Research focus: Autoimmunity, immune system disorders, immunopathology; infectious diseases/agents; Rheumatoid arthritis, atherosclerosis, breast cancer and the immune system, bone loss and erosion, alcoholic liver disease. |
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Wallace B. Thoreson, PhD Professor, Department of Ophthalmology and Visual Sciences Research focus: Visual information processing by the retina; electrophysiology and optical imaging techniques to study transmission at ribbon synapses of rod and cone photoreceptors. |
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Myron L. Toews, PhD Professor, Department of Pharmacology and Experimental Neuroscience Research focus: Regulation of G protein-coupled receptors and their signaling pathways; lysophosphatidic acid and its receptors in lung disease; epidermal growth factor receptors and protease signaling in agricultural dust-induced lung disease, oxytocin receptors and signaling in primate social behavior. |
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Matthew Van Hook, PhD Assistant Professor, Department of Ophthalmology and Visual Sciences Research focus: Influence of neurodegenerative disease of the visual system (i.e. glaucoma) on the function of neurons and synapses i the brain and retina. |
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Joseph Vetro, PhD Assistant Professor, College of Pharmacy Research focus: Developing novel synthetic targeted drug and gene delivery nanocarriers for the anti-angiogenesis treatment of cancer; improving development paradigms for targeted bioimaging and drug delivery nanocarriers; developing subunit vaccines based on the novel adjuvant, EP67. |
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Saraswathi Viswanathan, PhD Assistant Professor, Department of Internal Medicine - Diabetes, Endocrine and Metabolism Research focus: Determine the role of obesity in modulating the pathogenesis of insulin resistance, alcohol-associated liver injury, and pancreatic cancer. |
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Hanjun Wang, PhD Associate Professor, Department of Cellular and Integrative Physiology Research focus: Cardiovascular reflexes during exercise; neural control mechanisms underlying the exaggerated cardiovascular response and hyperventilation during exercise in the chronic heart failure state. |
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Sowmya Yelamanchili, PhD Assistant Professor, Department of Anesthesiology Research focus: MicroRNAs in neurodegenerative disease, HIV, Parkinson's Disease. |
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Chi (Kevin) Zhang, MD, PhD |
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Matthew C. Zimmerman, PhD Associate Professor, Department of Cellular and Integrative Physiology Research focus: Role of reactive oxygen species and redox signaling in the brain in the pathogenesis of cardiovascular disease; utilization of nanoformulated antioxidants for the improved treatment of cardiovascular disease. |
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Irving H. Zucker, PhD Professor, Department of Cellular and Integrative Physiology Research focus: Neural control of cardiovascular function; heart failure; hypertension; sympathetic function. |