Neurological Sciences

Howard Fox, PhD

Research Interests: The brain is a unique organ, not only functionally but also in terms of host response to events such as damage and infection. We study processes in which this response leads to neurodegeneration and brain dysfunction. One focus of our recent work is to discover biomarkers, which are objectively measured markers that correlate with disease states. They are useful for predicting risk of disease, development of disease, response to therapy, and other medical indications. Furthermore, they can give important clues to pathogenic mechanisms leading to means to prevent and treat disease, and we are actively following up such mechanistic clues in a variety of systems in the laboratory. There is a distinct lack of such biomarkers in neurodegenerative diseases, representing a significant gap in our biomedical knowledge which we aim to close.

For more information on Dr. Fox: Website