University of Nebraska Medical Center


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  1. Hashemi J, Patel B, Chatzizisis YS, Kassab GS. Real time reduced order model for angiography fractional flow reserve. Comput Methods Programs Biomed. 2022,216:106674. (PDF)
  2. Nikolakopoulos I, Vemmou E, Karacsonyi J, Azzalini L, Bergmark BA, Chatzizisis YS, Hall AB, Wollmuth J, Croce K, Jneid H, Rangan BV, Burke MN, Brilakis ES. Practice Patterns in the Interventional Treatment of Coronary Bifurcation Lesions: A Global Survey. J Invasive Cardiol. 2022,34(1):E43-E48. (PDF)
  3. Dhawan R, Samant S, Gajanan G, Chatzizisis YS. Case Report: ST-Elevation Myocardial Infarction Secondary to Acute Atherothrombotic Occlusion Treated With No Stent Strategy. Front Cardiovasc Med. 2022,9:834676. (PDF)


  1. Jhand A, Atti V, Gwon Y, Dhawan R, Turagam MK, Mamas MA, Brilakis ES, Kumar A, Katta N, Chatzizisis YS, Parikh M, Abbott JD, Kirtane AJ, Bhatt DL, Velagapudi P. Meta-Analysis of Transradial vs Transfemoral Access for Percutaneous Coronary Intervention in Patients With ST Elevation Myocardial Infarction. The American Journal of Cardiology. 2021,141:23-30. (PDF)
  2. Kumar A, Giannopoulos AA, Chatzizisis YS. The stenotic vulnerable plaque: Identifying the substrate of acute coronary syndromes. Atherosclerosis. 2021,320:95-97. (PDF)
  3. Korosoglou G, Chatzizisis YS, Raggi P. Coronary computed tomography angiography in asymptomatic patients: Still a taboo or precision medicine? Atherosclerosis. 2021,317:47-49. (PDF)
  4. Burzotta F, Lassen JF, Lefèvre T, Banning AP, Chatzizisis YS, Johnson TW, Ferenc M, Rathore S, Albiero R, Pan M, Darremont O, Hildick-Smith D, Chieffo A, Zimarino M, Louvard Y, Stankovic G. Percutaneous coronary intervention for bifurcation coronary lesions: the 15 th consensus document from the European Bifurcation Club. EuroIntervention2021,16(16):1307-1317. (PDF)
  5. Samant S, Wu W, Zhao S, Khan B, Sharzehee M, Panagopoulos A, Makadia J, Mickley T, Bicek A, Boismier D, Murasato Y, Chatzizisis YS. Computational and experimental mechanical performance of a new everolimus‑eluting stent purpose‑built for left main interventions. Scientific Reports2021,11: 8728. (PDF) 
  6. Hashemi J, Patel B, Chatzizisis YS, Kassab GS. Study of Coronary Atherosclerosis Using Blood Residence Time. Frontiers in Physiology. 2021,12:625420. (PDF)  
  7. Hall A, Chavez I, Garcia S, Gössl M, Poulose A, Sorajja P, Wang Y, Louvard Y, Chatzizisis YS, Banerjee S, Xenogiannis I, Burke MN, Brilakis ES. Double kissing crush bifurcation stenting: step-by-step
    troubleshooting. EuroIntervention. 2021,17(4):e317-e325. (PDF)
  8. Genuardi L, Chatzizisis YS, Chiastra C, Sgueglia G, Samady H, Kassab GS, Migliavacca F, Trani C, Burzotta F. Local fluid dynamics in patients with bifurcated coronary lesions undergoing percutaneous coronary interventions. Cardiology Journal. 2021,28(2):321-329. (PDF
  9. Grinnell M, Zhao M, O'Dell J, Sayyed S, Chatzizisis YS, Hearth-Holmes M. Granulomatosis With Polyangiitis Cardiomyopathy Versus Myocardial Infarction: Value of Magnetic Resonance Imaging and Positron Emission Tomography for Differentiation. J Clin Rheumatol. 2021,27(6):e210-e212. (PDF)
  10. Albulushi A, Kadir S, Barton D, Chatzizisis YS, O'Leary E. Blunt Chest Trauma Presenting with Acute Coronary Event. Oman Med J. 2021,36(3):e275. (PDF)
  11. Zhao S, Wu W, Samant S, Khan B, Kassab GS, Watanabe Y, Murasato Y, Sharzehee M, Makadia J, Zolty D, Panagopoulos A, Burzotta F, Migliavacca F, Johnson TW, Lefevre T, Lassen JF, Brilakis ES, Bhatt DL,  Dangas G, Chiastra C, Stankovic G, Louvard Y, Chatzizisis YS. Patient-specific computational simulation of coronary artery bifurcation stenting. Sci Rep. 2021,11(1):16486. (PDF)
  12. Dhawan R, Kadir S, Barton DE, Stone JR, Chatzizisis YS. Myocardial infarction secondary to coronary
    embolus in a patient with left ventricular non-compaction cardiomyopathy: a case report. Eur Heart J Case Rep. 2021,5(3):ytab077. (PDF


  1. Genuardi L, Chatzizisis YS, Chiastra C, Sgueglia G, Samady H, Kassab GS, Migliavacca F, Trani C, Burzotta F. Local fluid dynamics in patients with bifurcated coronary lesions undergoing percutaneous coronary interventions. Cardiology Journal. 2020. (PDF)
  2. Sarker S, Chatzizisis YS, Terry BS. Computational optimization of a novel atraumatic catheter for local drug delivery in coronary atherosclerotic plaques. Medical Engineering and Physics. 2020. (PDF
  3. Rengarajan B, Wu W, Wiedner C, Ko D, Muluk SC, Eskandari MK, Menon PG, Finol EA. A Comparative Classification Analysis of Abdominal Aortic Aneurysms by Machine Learning Algorithms. Annals of Biomedical Engineering. 2020,48(4):1419-1429. (PDF)
  4. Burzotta F, Lassen JF, Louvard Y, Lefèvre T, Banning AP, Daremont O, Pan M, Hildick-Smith D, Chieffo A, Chatzizisis YS, Džavík V, Gwon HC, Hikichi Y, Murasato Y, Koo BK, Chen SL, Serruys P, Stankovic G. European Bifurcation Club white paper on stenting techniques for patients with bifurcated coronary artery lesions. Catheter Cardiovasc Interv. 2020:1-13. (PDF
  5. Chatzizisis YS, Gajanan G, Bhatt DL, Dangas G, Porter T. Management of acute myocardial injury in patients with confirmed or suspected COVID-19. Atherosclerosis. 2020,305:58-60. (PDF)
  6. Chen HYChatzizisis YS, Louvard Y, Kassab GS. Computational Simulations of Provisional Stenting of a Diseased Coronary Artery Bifurcation Model. Scientific Report. 2020,10(1):9667. (PDF
  7. Goldsweig AM, Lyden E, Aronow HD, Kolte D, Pavlides G, Barton D, Chatzizisis YS, Gumina RJ, Abbott JD. Predictors of Contrast Volume in Transcatheter Aortic Valve Replacement. Cardiology2020,Jul 2:1-3. (PDF)
  8. Hall AB, Chavez I, Garcia S, Gössl M, Poulose A, Sorajja P, Wang Y, Louvard Y, Chatzizisis YS, Banerjee S, Xenogiannis I, Burke MN, Brilakis ES. Double-Kiss-Crush Bifurcation Stenting: Step-by-Step Troubleshooting. EuroIntervention. 2020, Apr 21. (PDF)
  9. Wu W, Samant S, de Zwart G, Zhao S, Khan B, Ahmad M, Bologna M, Watanabe Y, Murasato Y, Burzotta F, Brilakis ES, Dangas G, Louvard Y, Stankovic G, Kassab GS, Migliavacca F, Chiastra C, Chatzizisis YS. 3D Reconstruction of Coronary Artery Bifurcations from Coronary Angiography and Optical Coherence Tomography: Feasibility, Validation, and Reproducibility. Scientific Reports2020,10: 18049. (PDF)
  10. Lobo ASSandoval YHenriques JPDrakos SGTaleb IBagai JCohen MGChatzizisis YSSun BHryniewicz KEckman PMThiele HBrilakis ES. Cardiogenic Shock Management: International Survey of Contemporary Practices. J Invasive Cardiol. 2020,32(10):371-274. (PDF
  11. Barton DE, Hamilos M, Chatzizisis YS. Left main percutaneous coronary intervention versus coronary artery bypass surgery: A case of true equivalence in low and intermediate complexity anatomy or a question yet to be answered? Atherosclerosis. 2020,308:45-47. (PDF


  1. Chatzizisis YS. Complex Cardiovascular Interventions Visualization, Planning, Outcomes. JACC: Case Reports. 2019,1:124-126. (PDF)
  2. Mavrakanas TA, Chatzizisis YS, Gariani K, Kereiakes DJ, Gargiulo G, Helft G, Gilard M, Feres F, Costa RA, Morice MC, Georges JL, Valgimigli M, Bhatt DL, Mauri L, Charytan DM. Duration of Dual Antiplatelet Therapy in Patients with CKD and Drug-Eluting Stents: A Meta-AnalysisClinical Journal of the American Society of Nephrology2019,14:483-484. (PDF)
  3. Chen C, Chen J, Wu W, Shi Y, Jin L, Petrini L, Shen L, Yuan G, Ding W, Ge J, Edelman ER, Migliavacca F. In vivo and in vitro evaluation of a biodegradable magnesium vascular stent designed by shape optimization strategy. Biomaterials. 2019,221:119414. (PDF)
  4. Barton D, Xie F, O'Leary E, Chatzizisis YS, Pavlides G, Porter TR. The Relationship of Capillary Blood Flow Assessments with Real Time Myocardial Perfusion Echocardiography to Invasively Derived Microvascular and Epicardial Assessments. J Am Soc Echocardiogr. 2019, 32(9):1095-1101. (PDF)
  5. Wu W, Rengarajan B, Thirugnanasambandam M, Parikh S, Gomez R, De Oliveira V, Muluk SC, Finol EA. Wall stress and geometry measures in electively repaired abdominal aortic aneurysms. Annals of Biomedical Engineering. 2019,47(7):1611-1625. (PDF)
  6. Richez U, De Castilla H, Guerin CL, Gendron N, Luraghi G, Grimme M, Wu W, Taverna M, Jansen P, Latremouille C, Migliavacca F, Dubini G, Capel A, Carpentier A, Smadja DM. Hemocompatibility and safety of the Carmat Total Artificial Hearthybrid membrane. Heliyon. 2019,5:E02914. (PDF)


  1. Lambert LM, Pipinos II, Baxter BT, Chatzizisis YS, Ryu SJ, Leighton RI, Wei T. In vitro measurements of hemodynamic forces and their effects on endothelial cell mechanics at the sub-cellular level. Biomicrofluidics. 2018,12:064101. (PDF)
  2. Giannopoulos AA, Giannoglou GD, Chatzizisis YS. Predicting Coronary Atherosclerotic Plaque Burden From Clinical Parameters: Bringing Old Knowledge in the Game. Angiology. 2018,69:367-369. (PDF)
  3. Baibhav B, Gedela M, Moulton M, Pavlides G, Pompili V, Rab T, Dangas G, Bhatt DL, Siddique A, Chatzizisis YS. Role of Invasive Functional Assessment in Surgical Revascularization of Coronary Artery Disease. Circulation. 2018,137:1731-1739. (PDF)
  4. Gutiérrez-Chico JL, Zhao S, Chatzizisis YS. Vorticity: At the crossroads of coronary biomechanics and physiology. Atherosclerosis. 2018,273:115-116. (PDF)
  5. Karagiannis AD, Liu M, Toth PP, Zhao S, Agrawal DK, Libby P, Chatzizisis YS. Pleiotropic Anti-atherosclerotic Effects of PCSK9 Inhibitors From Molecular Biology to Clinical Translation. Curr Atheroscler Rep. 2018,20:20. (PDF)
  6. Giannopoulos AA, Zhao S, Chatzizisis YS. Rupture of a stenotic thin-cap fibroatheroma in an area of low endothelial shear stress Implication for mechanism of acute coronary syndromes. Eur Heart J Cardiovasc Imaging. 2018,19:950-951. (PDF)
  7. Giannopoulos AA, Mitsouras D, Bartykowszki A, Merkely B, Chatzizisis YS, Buechel RR, Kaufmann PA, Gaemperli O, Maurovich-Horvat P. High-Risk Plaque Regression and Stabilization: Hybrid Noninvasive Morphological and Hemodynamic Assessment. Circ Cardiovasc Imaging. 2018,11:e007888. (PDF)
  8. Albulushi A, Giannopoulos A, Kafkas N, Dragasis S, Pavlides G, Chatzizisis YS. Acute right ventricular myocardial infarction. Expert Rev Cardiovasc Ther. 2018,16:455-464. (PDF)
  9. Ormiston JA, Kassab G, Finet G, Chatzizisis YS, Foin N, Mickley TJ, Chiastra C, Murasato Y, Hikichi Y, Wentzel JJ, Darremont O, Iwasaki K, Lefèvre T, Louvard Y, Beier S, Hojeibane H, Netravali A, Wooton J, Brett Cowan, Webster MW, Medrano-Gracia P, Stankovic G. Bench testing and coronary artery bifurcations: a consensus document from the European Bifurcation Club. EuroIntervention. 2018,13:e1794-e1803. (PDF)
  10. Chatzizisis YS, Stefanadis C. Clash of Oral P2Y 12 Receptor Inhibitors in Acute Coronary Syndromes. J Am Coll Cardiol. 2018,71:382-385. (PDF)
  11. Asawaeer M, Sayyed S, Chatzizisis YS. A rare case of granulomatosis with polyangiitis-induced burnout cardiomyopathy: role of combined viability and metabolic imaging. Eur Heart J Cardiovasc Imaging. 2018,19:584. (PDF)
  12. Malik SA, Brilakis ES, Pompili V, Chatzizisis YS. Lost and found: Coronary stent retrieval and review of literature. Catheter Cardiovasc Interv. 2018,92:50-53. (PDF)
  13. Burzotta F, Lassen JF, Banning AP, Lefèvre T, Hildick-Smith D, Chieffo A, Darremont O, Pan M, Chatzizisis YS, Albiero R, Louvard Y, Stankovic G. Percutaneous coronary intervention in left main coronary artery disease: the 13th consensus document from the European Bifurcation Club. EuroIntervention. 2018,14:112-120. (PDF)
  14. Kishi S, Giannopoulos AA, Tang A, Kato N, Chatzizisis YS, Dennie C, Horiuchi Y, Tanabe K, Lima JAC, Rybicki FJ, Mitsouras D. Fractional Flow Reserve Estimated at Coronary CT Angiography in Intermediate Lesions: Comparison of Diagnostic Accuracy of Different Methods to Determine Coronary Flow Distribution. Radiology. 2018,287:76-84. (PDF)
  15. Al Emam AR, Moulton M, Hyden M, Chatzizisis Y. A Giant Aortic Root Abscess. Methodist Debakey Cardiovasc J. 2018,14:150. (PDF)
  16. Giannopoulos AA, Chatzizisis YS. Building Coronary Lesion-Specific Predictive Models Using the Proper Prognostic Parameters: A Look Into the Computational Hemodynamics of the Matter. JACC Cardiovasc Imaging. 2018,11:1371-1372. (PDF
  17. Asawaeer M, Barton D, Radio S, Chatzizisis YS. Tyrosine Kinase Inhibitor-Induced Acute Myocarditis, Myositis, and Cardiogenic Shock. Methodist DeBakey Cardiovasc J. 2018,14:e5-6. (PDF)
  18. Kumar A, Santos-Gallego CG, Chatzizisis YS. T2 magnetic resonance mapping: The key to find the 'Brahmastra' against atherosclerosis? Atherosclerosis. 2018. (PDF)
  19. Grinnell M, Zhao M, OʼDell J, Sayyed S, Chatzizisis YS, Hearth-Holmes M.Granulomatosis With Polyangiitis Cardiomyopathy Versus Myocardial Infraction: Value of Magnetic Resonance Imaging and Positron Emission Tomography for Differentiation. J Clin Rheumatol. 2018. (PDF)
  20. Ang HY, Toong D, Chow WS, Seisilysa W, Wu W, Wong P, Venkatraman S. Radiopaque Fully Degradable Nanocomposites for Coronary Stents. Scientific Reports. 2018,8:17409. (PDF
  21. Morris PD, Iqbal J, Chiastra C, Wu W, Migliavacca F, Gunn JP. Simultaneous kissing stents to treat unprotected left main stem coronary artery bifurcation disease; stent expansion, vesse injury, hemodynamics, tissue healing, restenosis, and repeat revascularization. Catheter Cardiovasc Interv2018,92:E381–E392. (PDF
  22. Grundeken MJ, Chiastra C, Wu W, Wykrzykowska JJ, De Winter RJ, Dubini G, Migliavacca F. Differences in rotational positioning and subsequent distal main branch rewiring of the Tryton stent: An optical coherence tomography and computational study. Catheter Cardiovasc Interv. 2018,92:897–906. (PDF)
  23. Chiastra C, Grundeken MJ, Collet C, Wu W, Wykrzykowska JJ, Pennati G, Dubini G, Migliavacca F. Biomechanical impact of wrong positioning of a dedicated stent for coronary bifurcations: a virtual bench testing study. Cardiovascular engineering and technology. 2018,9(3):415-426. (PDF)
  24. Ariza-Gracia MA, Wu W, Malve M, Calvo B, Rodriguez Matas JF. Fluid structure interaction of the non-contact tonometry test. Journal for Modeling in Ophthalmology. 2018,2(2):75-79. (PDF)
  25. Chen C, Tan J, Wu W, Petrini L, Zhang L, Shi Y, Cattarinuzzi E, Pei J, Huang H, Ding W, Yuan G, Migliavacca F. Modeling and experimental studies of coating delamination of biodegradable magnesium alloy cardiovascular stents. ACS Biomaterials Science & Engineering. 2018,4(11):3864-3873. (PDF)
  26. Migliavacca F, Luraghi G, Wu W, De Castilla H, Rodriguez Matas JF, Dubini G, Dubuis P, Grimmé M. Numerical approach to study the behavior of an artificial ventricle: fluid-structure interaction followed by fluid dynamics with moving boundaries. Artificial Organs. 2018,42(10):E315–E324. (PDF)
  27. Ariza-Gracia MA, Wu W, Calzada BC, Malvè M, Büchler P, Rodríguez Matas JF. Fluid–structure simulation of a general non-contact. A required complexity? Computer Methods in Applied Mechanics and Engineering. 2018,340:202-215. (PDF)


  1. Malik SA, Porter TT, Pavlides G, Chatzizisis YS. Vasospastic Angina Presenting With Syncope and Chest Pain: A Case Report and Brief Literature Review. S D Med. 2017,70:498-502. (PDF)
  2. Cheimariotis GA, Chatzizisis YS, Koutkias VG, Toutouzas K, Giannopoulos A, Riga M, Chouvarda I, Antoniadis AP, Doulaverakis C, Tsamboulatidis I, Kompatsiaris I, Giannoglou GD, Maglaveras N. ARCOCT: Automatic detection of lumen border in intravascular OCT images. Comput Methods Programs Biomed. 2017,151:21-32. (PDF)
  3. Selim A, Zolty R, Chatzizisis YS. New heart failure pharmacotherapy in clinical trials: a hope in progress. Expert Rev Cardiovasc Ther. 2017,15:649-651. (PDF)
  4. Shah NR, Cheezum MK, Motoyama S, Chatzizisis YS. Do we really need another individual coronary plaque characterization measurement? Atherosclerosis. 2017,261:160-162. (PDF)
  5. Franck G, Mawson T, Sausen G, Salinas M, Masson GS, Cole A, Beltrami-Moreira M, Chatzizisis YS, Quillard T, Tesmenitsky Y, Shvartz E, Sukhova GK, Swirski FK, Nahrendorf M, Aikawa E, Croce KJ, Libby P. Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice: Implications for Superficial Erosion. Circ Res. 2017,121:31-42. (PDF)
  6. Selim A, Zolty R, Chatzizisis YS.The evolution of heart failure with reduced ejection fraction pharmacotherapy: What do we have and where are we going? Pharmacol Ther. 2017,178:67-82. (PDF)
  7. Huang D, Muramatsu T, Li Y, Yang W, Nagahara Y, Chu M, Kitslaar P, Sarai M, Ozaki Y, Chatzizisis YS, Yan F, Reiber JHC, Wu R, Pu J, Tu S. Assessment of endothelial shear stress in patients with mild or intermediate coronary stenoses using coronary computed tomography angiography: comparison with invasive coronary angiography. Int J Cardiovasc Imaging. 2017,33:1101-1110. (PDF)
  8. Chatzizisis YS, Toutouzas K, Giannopoulos AA, Riga M, Antoniadis AP, Fujinom Y, Mitsouras D, Koutkias VG, Cheimariotis G, Doulaverakis C, Tsampoulatidis I, Chouvarda I, Kompatsiaris I, Nakamura S, Rybicki FJ, Maglaveras N, Tousoulis D, Giannoglou GD. Association of global and local low endothelial shear stress with high-risk plaque using intracoronary 3D optical coherence tomography: Introduction of 'shear stress score'. Eur Heart J Cardiovasc Imaging. 2017,18:888-897. (PDF)
  9. Gitsioudis G, Chatzizisis YS, Wolf P, Missiou A, Antoniadis AP, Mitsouras D, Bartling S, Arica Z, Stuber M, Rybicki FJ, Nunninger M, Erbel C, Libby P, Giannoglou GD, Katus HA, Korosoglou G. Combined non-invasive assessment of endothelial shear stress and molecular imaging of inflammation for the prediction of inflamed plaque in hyperlipidaemic rabbit aortas. Eur Heart J Cardiovasc Imaging. 2017,18:19-30. (PDF)
  10. Giannoglou GD, Giannopoulos AA, Chatzizisis YS. Lowering Heart Rate Post Revascularization: Angina and Quality of Life Improvement. Angiology. 2017,68:5-7. (PDF)


  1. Antoniadis AP, Stone PH, Chatzizisis YS. Foretelling plaque disruption: Is the journey to Ithaca reaching destination? Atherosclerosis. 2016,244:147-148. (PDF)
  2. Giannopoulos AA, Antoniadis AP, Croce K, Chatzizisis YS. Erosion of Thin-Cap Fibroatheroma in an Area of Low Endothelial Shear Stress: Anatomy and Local Hemodynamic Environment Dictate Outcomes. JACC Cardiovasc Interv. 2016,9:e77-78. (PDF)
  3. Tsigkas N, Kidambi S, Tawakol A, Chatzizisis YS. Drug-loaded particles: "Trojan horses" in the therapy of atherosclerosis. Atherosclerosis. 2016,251:528-530. (PDF)
  4. Giannopoulos AA, Mitsouras D, Yoo SJ, Liu PP, Chatzizisis YS, Rybicki FJ. Applications of 3D printing in cardiovascular diseases. Nat Rev Cardiol. 2016,13:701-718. (PDF)
  5. Antoniadis AP, Papafaklis MI, Takahashi S, Shishido K, Andreou I, Chatzizisis YS, Tsuda M, Mizuno S, Makita Y, Domei T, Ikemoto T, Coskun AU, Honye J, Nakamura S, Saito S, Edelman ER, Feldman CL, Stone PH. Arterial Remodeling and Endothelial Shear Stress Exhibit Significant Longitudinal Heterogeneity Along the Length of Coronary Plaques. JACC Cardiovasc Imaging. 2016,9:1007-1009. (PDF)
  6. Giannopoulos AA, Chatzizisis YS, Maurovich-Horvat P, Antoniadis AP, Hoffmann U, Steigner ML, Rybicki FJ, Mitsouras D. Quantifying the effect of side branches in endothelial shear stress estimates. Atherosclerosis. 2016,251:213-218. (PDF)
  7. Carreras ET, Chatzizisis YS, Mauri L, MacRae C. Acute Coronary Syndrome in a 52-Year-Old Woman With Scleroderma. Circulation. 2016,133:2576-2582. (PDF)
  8. Giannopoulos AA, Giannoglou GD, Chatzizisis YS. Refractory angina: new drugs on the block. Expert Rev Cardiovasc Ther. 2016,14:881-883. (PDF)
  9. Giannopoulos AA, Giannoglou GD, Chatzizisis YS. Pharmacological approaches of refractory angina. Pharmacol Ther. 2016,163:118-131. (PDF)
  10. George E, Giannopoulos AA, Aghayev A, Rohatgi S, Imanzadeh A, Antoniadis AP, Kumamaru KK, Chatzizisis YS, Dunne R, Steigner M, Hanley M, Gravereaux EC, Rybicki FJ, Mitsouras D. Contrast inhomogeneity in CT angiography of the abdominal aortic aneurysm. J Cardiovasc Comput Tomogr. 2016,10:179-183. (PDF
  11. Vergallo R, Aguirre AD, Abtahian F, Minami Y, Soeda T, Chatzizisis YS, Croce K, Jang IK. Recurrent myocardial infarctions and premature coronary atherosclerosis in a 23-year-old man with antiphospholipid syndrome. Thromb Haemost. 2016,115:237-239. (PDF


  1. Andreou I, Antoniadis AP, Shishido K, Papafaklis MI, Koskinas KC, Chatzizisis YS, Coskun AU, Edelman ER, Feldman CL, Stone PH. How do we prevent the vulnerable atherosclerotic plaque from rupturing? Insights from in vivo assessments of plaque, vascular remodeling, and local endothelial shear stress. J Cardiovasc Pharmacol Ther. 2015,20:261-275. (PDF)
  2. Antoniadis AP, Giannopoulos AA, Wentzel JJ, Joner M, Giannoglou GD, Virmani R, Chatzizisis YS. Impact of local flow haemodynamics on atherosclerosis in coronary artery bifurcations. EuroIntervention. 2015,11 Suppl V:V18-22. (PDF)
  3. Antoniadis AP, Mortier P, Kassab G, Dubini G, Foin N, Murasato Y, Giannopoulos AA, Tu S, Iwasaki K, Hikichi Y, Migliavacca F, Chiastra C, Wentzel JJ, Gijsen F, Reiber JH, Barlis P, Serruys PW, Bhatt DL, Stankovic G, Edelman ER, Giannoglou GD, Louvard Y, Chatzizisis YS. Biomechanical Modeling to Improve Coronary Artery Bifurcation Stenting: Expert Review Document on Techniques and Clinical Implementation. JACC Cardiovasc Interv. 2015,8:1281-1296. (PDF)
  4. Giannopoulos AA, Antoniadis AP, Croce KJ, Chatzizisis YS. Advanced anatomical and functional imaging guides management of coronary artery ulcerated plaque. Eur Heart J Cardiovasc Imaging. 2015,16:1042. (PDF)
  5. Migliavacca F, Chiastra C, Chatzizisis YS, Dubini G. Virtual bench testing to study coronary bifurcation stenting. EuroIntervention. 2015,11 Suppl V:V31-34. (PDF)
  6. Toutouzas K, Benetos G, Karanasos A, Chatzizisis YS, Giannopoulos AA, Tousoulis D. Vulnerable plaque imaging: updates on new pathobiological mechanisms. Eur Heart J. 2015,36:3147-3154. (PDF)
  7. Toutouzas K, Chatzizisis YS, Riga M, Giannopoulos A, Antoniadis AP, Tu S, Fujino Y, Mitsouras D, Doulaverakis C, Tsampoulatidis I, Koutkias VG, Bouki K, Li Y, Chouvarda I, Cheimariotis G, Maglaveras N, Kompatsiaris I, Nakamura S, Reiber JH, Rybicki F, Karvounis H, Stefanadis C, Tousoulis D, Giannoglou GD. Accurate and reproducible reconstruction of coronary arteries and endothelial shear stress calculation using 3D OCT: comparative study to 3D IVUS and 3D QCA. Atherosclerosis. 2015,240:510-519. (PDF)
  8. Dale MA, Suh MK, Zhao S, Meisinger T, Gu L, Swier VJ, Agrawal DK, Greiner TC, Carson JS, Baxter TB, Xiong W. Background differences in baseline and stimulated MMP levels influence abdominal aortic aneurysm susceptibility. Atherosclerosis. 2015,243:621-629. (PDF)
  9. Zhao S, Stamm A, Lee JS, Gruberman A, Lim JY, Gu L. Elasticity of Differentiated and Undifferentiated Human Neuroblastoma Cells Characterized by Atomic Force Microscopy. J Mech Med Biol. 2015,15:1550069. (PDF)
  10. Dakos G, Konstantinou D, Chatzizisis YS, Chouvarda I, Filos D, Paraskevaidis S, Mantziari L, Maglaveras N, Karvounis H, Vassilikos V. P wave analysis with wavelets identifies hypertensive patients at risk of recurrence of atrial fibrillation: A case-control study and 1year follow-up. J Electrocardiol. 2015,48:845-852. (PDF)
  11. Mavrakanas TA, Chatzizisis YS. Bivalirudin in ST-segment-elevation myocardial infarction: for better or worse? Expert Rev Cardiovasc Ther. 2015,13:893-895. (PDF)
  12. Ferencik M, Chatzizisis YS. Statins and the coronary plaque calcium "paradox": Insights from non-invasive and invasive imaging. Atherosclerosis. 2015,241:783-785. (PDF)
  13. Saboo SS, Abbara S, Rybicki FJ, Chatzizisis YS. Quantification of aortic calcification - how and why should we do it? Atherosclerosis. 2015,240:469-471. (PDF)
  14. Mavrakanas TA, Chatzizisis YS. Bivalirudin in stable angina and acute coronary syndromes. Pharmacol Ther. 2015,152:1-10. (PDF)


  1. Chatzizisis YS, Antoniadis AP, Wentzel JJ, Giannoglou GD. Vulnerable plaque: the biomechanics of matter. Atherosclerosis. 2014,236:351-352. (PDF)
  2. Chatzizisis YS, Blankstein R, Libby P. Inflammation goes with the flow: implications for non-invasive identification of high-risk plaque. Atherosclerosis. 2014,234:476-478. (PDF)
  3. Chatzizisis YS, George E, Cai T, Fulwadhva UP, Kumamaru KK, Schultz K, Fujisawa Y, Rassi C, Steigner M, Mather RT, Blankstein R, Rybicki FJ, Mitsouras D. Accuracy and reproducibility of automated, standardized coronary transluminal attenuation gradient measurements. Int J Cardiovasc Imaging. 2014,30:1181-1189. (PDF)
  4. Chatzizisis YS, Koutkias VG, Toutouzas K, Giannopoulos A, Chouvarda I, Riga M, Antoniadis AP, Cheimariotis G, Doulaverakis C, Tsampoulatidis I, Bouki K, Kompatsiaris I, Stefanadis C, Maglaveras N, Giannoglou GD. Clinical validation of an algorithm for rapid and accurate automated segmentation of intracoronary optical coherence tomography images. Int J Cardiol. 2014,172:568-580. (PDF)
  5. Zhao S, Gu L. Implementation and Validation of Aortic Remodeling in hypertensive rats. J Biomech Eng. 2014,136:091007. (PDF)
  6. Juan YH, Chatzizisis YS, Saboo SS, Rocha T, Steigner ML. Tumor encasement of the right coronary artery: role of anatomic and functional imaging in diagnosis and therapeutic management. Open Cardiovasc Med J. 2014,8:110-112. (PDF)
  7. Hucker WJ, Chatzizisis YS, Steigner ML, Winters GL, Kirshenbaum JM. Myocardial catastrophe: a case of sudden, severe myocardial dysfunction. Circulation. 2014,130:854-862. (PDF)
  8. Giannoglou GD, Chatzizisis YS. Heart rate lowering reduces cardiovascular disease burden. Curr Med Res Opin. 2014,30:1757. (PDF)
  9. Dakos G, Chatzizisis YS, Konstantinou D, Chouvarda I, Filos D, Paraskevaidis S, Mantziari L, Maglaveras N, Karvounis H, Styliadis I, Vassilikos V. Wavelet-based analysis of P waves identifies patients with lone atrial fibrillation: a cross-sectional pilot study. Int J Cardiol. 2014,174:389-392. (PDF)
  10. Juan YH, Saboo SS, Anand V, Chatzizisis YS, Lin YC, Steigner ML. Superior vena cava syndrome associated with right-to-left shunt through systemic-to-pulmonary venous collaterals. Korean J Radiol. 2014,15:185-187. (PDF
  11. Juan YH, Chatzizisis YS, Saboo SS, Newburger JW, Steigner ML. Hypoplastic left coronary artery with large collateral vessels from an ectatic right coronary artery: multimodality imaging-based diagnostic work-up. Int J Cardiol. 2014,172:e396-397. (PDF)
  12. Waller AH, Chatzizisis YS, Moslehi JJ, Chen FY, Mangion JR. Real-time three-dimensional transoesophageal echocardiography enables preoperative pulmonary valvulopathy assessment. Eur Heart J Cardiovasc Imaging. 2014,15:713. (PDF
  13. Ghosh N, Waller AH, Rinehart E, Lakdawala NK, Chatzizisis YS, Padera R, Couper G, Mangion J, Steigner M. Multimodality imaging for the assessment of total artificial heart function: complementary utility of 2- and 3-dimensional transesophageal echocardiography and computed tomography. J Am Coll Cardiol. 2014,63:e7. (PDF)
  14. Vassilikos VP, Mantziari L, Dakos G, Kamperidis V, Chouvarda I, Chatzizisis YS, Kalpidis P, Theofilogiannakos E, Paraskevaidis S, Karvounis H, Mochlas S, Maglaveras N, Styliadis IH. QRS analysis using wavelet transformation for the prediction of response to cardiac resynchronization therapy: a prospective pilot study. J Electrocardiol. 2014,47:59-65. (PDF
  15. Katranas SA, Kelekis AL, Antoniadis AP, Chatzizisis YS, Giannoglou GD. Association of remodeling with endothelial shear stress, plaque elasticity, and volume in coronary arteries: a pilot coronary computed tomography angiography study. Angiology. 2014,65:413-419. (PDF)
  16. Chatzizisis YS, Ziakas A, Feloukidis C, Paramythiotis D, Hadjimiltiades S, Iliadis A, Basdanis G, Styliadis I. Pheochromocytoma crisis presenting with cardiogenic shock. Herz. 2014,39:156-160. (PDF)


  1. Doulaverakis C, Tsampoulatidis I, Antoniadis AP, Chatzizisis YS, Giannopoulos A, Kompatsiaris I, Giannoglou GD. IVUSAngio tool: a publicly available software for fast and accurate 3D reconstruction of coronary arteries. Comput Biol Med. 2013,43:1793-1803. (PDF)
  2. Koskinas KC, Chatzizisis YS, Papafaklis MI, Coskun AU, Baker AB, Jarolim P, Antoniadis A, Edelman ER, Stone PH, Feldman CL. Synergistic effect of local endothelial shear stress and systemic hypercholesterolemia on coronary atherosclerotic plaque progression and composition in pigs. Int J Cardiol. 2013,169:394-401. (PDF)
  3. Koskinas KC, Sukhova GK, Baker AB, Papafaklis MI, Chatzizisis YS, Coskun AU, Quillard T, Jonas M, Maynard C, Antoniadis AP, Shi GP, Libby P, Edelman ER, Feldman CL, Stone PH. Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress. Arterioscler Thromb Vasc Biol. 2013,33:1494-1504. (PDF)
  4. Zhao S, Gu L, Froemming SR. Experimental investigation of the stent–artery interaction. J Med Eng Technol. 2013,37:463-469. (PDF)
  5. Gutierrez A, Chatzizisis YS, Rao SV. Progression of radial approach to PCI in the USA: from niche procedure to default approach. Expert Rev Cardiovasc Ther. 2013,11:1271-1273. (PDF)
  6. Paraskevaidis S, Theofilogiannakos EK, Kamperidis V, Chatzizisis YS, Tsilonis K, Vassilikos VP, Dakos G, Stavropoulos G, Ziakas A, Hadjimiltiades S, Styliadis IH. Quinidine: an "endangered species" drug appropriate for management of electrical storm in brugada syndrome. Indian Pacing Electrophysiol J. 2013,13:178-180. (PDF
  7. Chatzizisis YS, Murthy VL, Solomon SD. Echocardiographic evaluation of coronary artery disease. Coron Artery Dis. 2013,24:613-623. (PDF
  8. Saboo SS, Chatzizisis YS, Khandelwal A, Blankstein R. Acute coronary syndrome unmasking a puzzling coronary anatomy: role of multimodality anatomic and functional imaging. Eur Heart J. 2013,34:3089. (PDF
  9. Konstantinou DM, Chatzizisis YS, Giannoglou GD. Heart failure with preserved ejection fraction: future directions in medical treatment. Expert Rev Cardiovasc Ther. 2013,11:1085-1087. (PDF
  10. Nelson KH, Chatzizisis YS, Steigner ML, Mitchell RN, Blankstein R, Givertz MM. Cardiac allograft involvement by post-transplantation lymphoproliferative disorder. J Am Coll Cardiol. 2013,62:937. (PDF)  
  11. Konstantinou DM, Chatzizisis YS, Giannoglou GD. Pathophysiology-based novel pharmacotherapy for heart failure with preserved ejection fraction. Pharmacol Ther. 2013,140:156-166. (PDF)  
  12. Saboo SS, Chatzizisis YS, Khandelwal A, Bolman RM 3rd, Steigner M. Multimodality imaging of aortic valve fibroelastoma. Eur Heart J Cardiovasc Imaging. 2013,14:834. (PDF)  


  1. Giannoglou GD, Chatzizisis YS. Atherosclerosis: what are we looking for? Angiology. 2012,63:397-399. (PDF)
  2. Giannopoulos A, Chatzizisis YS, Giannoglou GD. Optical coherence tomography: an arrow in our quiver. Expert Rev Cardiovasc Ther. 2012,10:539-541. (PDF)
  3. Koskinas KC, Chatzizisis YS, Antoniadis AP, Giannoglou GD. Role of endothelial shear stress in stent restenosis and thrombosis: pathophysiologic mechanisms and implications for clinical translation. J Am Coll Cardiol. 2012,59:1337-1349. (PDF)
  4. Papafaklis MI, Chatzizisis YS, Naka KK, Giannoglou GD, Michalis LK. Drug-eluting stent restenosis: effect of drug type, release kinetics, hemodynamics and coating strategy. Pharmacol Ther. 2012,134:43-53. (PDF)
  5. Wentzel JJ, Chatzizisis YS, Gijsen FJ, Giannoglou GD, Feldman CL, Stone PH. Endothelial shear stress in the evolution of coronary atherosclerotic plaque and vascular remodelling: current understanding and remaining questions. Cardiovasc Res. 2012,96:234-243. (PDF)
  6. Zhao S, Gu L, Froemming SR. On the importance of modeling stent procedure for predicting arterial mechanics. J Biomech Eng. 2012,134:121005. (PDF)
  7. Zhao S, Gu L, Froemming SR. Effects of arterial strain and stress in the prediction of restenosis risk: Computer modeling of stent trials. Biomed Eng Lett. 2012,2:158-163. (PDF)
  8. Zhao S, Gu L, Froemming SR. Performance of self-expanding Nitinol stent in a curved artery: impact of stent length and deployment orientation. J Biomech Eng. 2012,134:071007. (PDF)
  9. Gu L, Zhao S, Froemming SR. Arterial wall mechanics and clinical implications after coronary stenting: comparisons of three stent designs. Int J Appl Mech. 2012,4:1250013. (PDF)
  10. Zhao S, Gu L, Froemming SR. Finite element analysis of the implantation of a self-expanding stent: impact of lesion calcification. J Med Devices. 2012,6:021001. (PDF)
  11. Zhao S, Liu XC, Gu L. The impact of wire stent fabrication technique on the performance of stent placement. J Med Devices. 2012,6:011007. (PDF)
  12. Konstantinou DM, Chatzizisis YS, Farmakis G, Styliadis I, Giannoglou GD. Cholesterol embolization syndrome following thrombolysis during acute myocardial infarction. Herz. 2012,37:231-233. (PDF)


  1. Chatzizisis YS, Baker AB, Sukhova GK, Koskinas KC, Papafaklis MI, Beigel R, Jonas M, Coskun AU, Stone BV, Maynard C, Shi GP, Libby P, Feldman CL, Edelman ER, Stone PH. Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs. Circulation. 2011,123:621-630. (PDF)
  2. Chatzizisis YS, Giannoglou GD. Importance of local hemodynamic conditions in the atherosclerotic effect of increased heart rate. J Am Coll Cardiol. 2011,57:2206. (PDF)
  3. Katranas SA, Kelekis AL, Antoniadis AP, Chatzizisis YS, Theodoridis TF, Tzanis AP, Giannoglou GD. Non-invasive assessment of endothelial shear stress and coronary stiffness using multislice computed tomography. Int J Cardiol. 2011,152:281-284. (PDF)
  4. Zhao S, Gu L, Froemming SR. Assessment of shape memory alloy stent deployment in a stenosed artery. Biomed Eng Lett. 2011,1:226-231. (PDF)
  5. Gu L, Kasavajhala ARM, Zhao S. Finite element analysis of cracks in aging aircraft structures with bonded composite-patch repairs. Compos Part B-Eng. 2011,42:505-510. (PDF)
  6. Mantziari AA, Vassilikos VP, Chatzizisis YS, Dakos G, Stavropoulos G, Paraskevaidis S, Styliadis IH. Cardiac arrest caused by torsades de pointes tachycardia after successful atrial flutter radiofrequency catheter ablation. Open Cardiovasc Med J. 2011,5:1-3. (PDF)
  7. Vaklavas C, Chatzizisis YS, Tsimberidou AM. Common cardiovascular medications in cancer therapeutics. Pharmacol Ther. 2011,130:177-190. (PDF)
  8. Vaklavas C, Chatzizisis YS. The changing perspective of cardiology in cancer care. Expert Rev Cardiovasc Ther. 2011,9:1-3. (PDF)
  9. Paraskevaidis S, Kamperidis V, Theofilogiannakos E, Chatzizisis YS, Vassilikos V, Boufidou A, Stavropoulos G, Dakos G, Gavrielidis S, Styliadis I. Brugada syndrome associated with supraventricular tachycardia: diagnostic and therapeutic strategies. Herz. 2011,36:724-727. (PDF)
  10. Koskinas KC, Chatzizisis YS, Kamperidis V, Anastasiadis K, Zioga C, Hadjimiltiades S, Giannoglou GD. Extremely rare case of primary cardiac chondroma in a patient presenting with acute pulmonary edema. Cardiovasc Pathol. 2011,20:374-376. (PDF
  11. Vassilikos V, Dakos G, Chatzizisis YS, Chouvarda I, Karvounis C, Maynard C, Maglaveras N, Paraskevaidis S, Stavropoulos G, Styliadis CI, Mochlas S, Styliadis I. Novel non-invasive P wave analysis for the prediction of paroxysmal atrial fibrillation recurrences in patients without structural heart disease: a prospective pilot study. Int J Cardiol. 2011,153:165-172. (PDF


  1. Baker AB, Chatzizisis YS, Beigel R, Jonas M, Stone BV, Coskun AU, Maynard C, Rogers C, Koskinas KC, Feldman CL, Stone PH, Edelman ER. Regulation of heparanase expression in coronary artery disease in diabetic, hyperlipidemic swine. Atherosclerosis. 2010,213:436-442. (PDF)
  2. Chatzizisis YS, Giannoglou GD. Shear stress and inflammation: are we getting closer to the prediction of vulnerable plaque? Expert Rev Cardiovasc Ther. 2010,8:1351-1353. (PDF)
  3. Giannoglou GD, Antoniadis AP, Koskinas KC, Chatzizisis YS. Flow and atherosclerosis in coronary bifurcations. EuroIntervention. 2010,6 Suppl J:J16-23. (PDF)
  4. Koskinas KC, Feldman CL, Chatzizisis YS, Coskun AU, Jonas M, Maynard C, Baker AB, Papafaklis MI, Edelman ER, Stone PH. Natural history of experimental coronary atherosclerosis and vascular remodeling in relation to endothelial shear stress: a serial, in vivo intravascular ultrasound study. Circulation. 2010,121:2092-2101. (PDF)
  5. Papafaklis MI, Koskinas KC, Chatzizisis YS, Stone PH, Feldman CL. In-vivo assessment of the natural history of coronary atherosclerosis: vascular remodeling and endothelial shear stress determine the complexity of atherosclerotic disease progression. Curr Opin Cardiol. 2010,25:627-638. (PDF)
  6. Gu L, Zhao S, Muttyam AK, Hammel JM. The relation between the arterial stress and restenosis rate after coronary stenting. J Med Devices. 2010,4:031005. (PDF)
  7. Paraskevaidis S, Theofilogiannakos EK, Chatzizisis YS, Mantziari L, Economou F, Ziakas A, Hadjimiltiades S, Styliadis IH. Spontaneous dissection of right coronary artery manifested with acute myocardial infarction. Open Cardiovasc Med J. 2010,4:178-180. (PDF)
  8. Chatzizisis YS, Saravakos P, Boufidou A, Parharidou D, Styliadis I. Acute myocardial infarction manifested with headache. Open Cardiovasc Med J. 2010,4:148-150. (PDF)  
  9. Konstantinou DM, Chatzizisis YS, Louridas GE, Parcharidis GE, Giannoglou GD. Non-diabetic hyperglycaemia correlates with angiographic coronary artery disease prevalence and severity. Diabetes Metab. 2010,36:402-408. (PDF)  
  10. Giannoglou GD, Antoniadis AP, Chatzizisis YS, Louridas GE. Difference in the topography of atherosclerosis in the left versus right coronary artery in patients referred for coronary angiography. BMC Cardiovasc Disord. 2010,10:26. (PDF)  
  11. Giannoglou GD, Konstantinou DM, Kovatsi L, Chatzizisis YS, Mikhailidis DP. Association of reduced zinc status with angiographically severe coronary atherosclerosis: a pilot study. Angiology. 2010,61:449-455. (PDF)
  12. Chatzizisis YS, Koskinas KC, Misirli G, Vaklavas C, Hatzitolios A, Giannoglou GD. Risk factors and drug interactions predisposing to statin-induced myopathy: implications for risk assessment, prevention and treatment. Drug Saf. 2010,33:171-187. (PDF)
  13. Konstantinou DM, Chatzizisis YS, Louridas GE, Giannoglou GD. Metabolic syndrome and angiographic coronary artery disease prevalence in association with the Framingham risk score. Metab Syndr Relat Disord. 2010,8:201-208. (PDF)
  14. Katsiki N, Tziomalos K, Chatzizisis Y, Elisaf M, Hatzitolios AI. Effect of HMG-CoA reductase inhibitors on vascular cell apoptosis: beneficial or detrimental? Atherosclerosis. 2010,211:9-14. (PDF


  1. Koskinas KC, Chatzizisis YS, Baker AB, Edelman ER, Stone PH, Feldman CL. The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaque. Curr Opin Cardiol. 2009,24:580-590. (PDF)
  2. Chatzizisis YS, Jonas M, Beigel R, Coskun AU, Baker AB, Stone BV, Maynard C, Gerrity RG, Daley W, Edelman ER, Feldman CL, Stone PH. Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaques. Atherosclerosis. 2009,203:387-394. (PDF)
  3. Giannoglou GD, Antoniadis AP, Chatzizisis YS, Louridas GE. Adult congenital heart disease investigated with cardiac catheterization over a 20-year period. Open Cardiovasc Med J. 2009,3:124-127. (PDF)
  4. Vaklavas C, Chatzizisis YS, Ziakas A, Zamboulis C, Giannoglou GD. Molecular basis of statin-associated myopathy. Atherosclerosis. 2009,202:18-28. (PDF)
  5. Paraskevaidis S, Stavropoulos G, Vassilikos V, Chatzizisis YS, Polymeropoulos K, Ziakas A, Dakos G, Parcharidis GE. Idiopathic left ventricular aneurysm causing ventricular tachycardia with 1:1 ventriculoatrial conduction and intermittent wenckebach block. Open Cardiovasc Med J. 2009,3:105-109. (PDF)
  6. Chatzizisis YS, Giannoglou GD. Myocardial bridges spared from atherosclerosis: overview of the underlying mechanisms. Can J Cardiol. 2009,25:219-222. (PDF)


  1. Chatzizisis YS, Jonas M, Coskun AU, Beigel R, Stone BV, Maynard C, Gerrity RG, Daley W, Rogers C, Edelman ER, Feldman CL, Stone PH. Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history study. Circulation. 2008,117:993-1002. (PDF)
  2. Chatzizisis YS, Vaklavas C, Giannoglou GD. Coenzyme Q10 depletion: etiopathogenic or predisposing factor in statin associated myopathy? Am J Cardiol. 2008,101:1071. (PDF)
  3. Chatzizisis YS, Misirli G, Hatzitolios AI, Giannoglou GD. The syndrome of rhabdomyolysis: complications and treatment. Eur J Intern Med. 2008,19:568-574. (PDF)
  4. Antoniadis AP, Chatzizisis YS, Giannoglou GD. Pathogenetic mechanisms of coronary ectasia. Int J Cardiol. 2008,130:335-343. (PDF)
  5. Papadogiorgaki M, Mezaris V, Chatzizisis YS, Giannoglou GD, Kompatsiaris I. Image analysis techniques for automated IVUS contour detection. Ultrasound Med Biol. 2008,34:1482-1498. (PDF)
  6. Giannoglou GD, Antoniadis AP, Chatzizisis YS, Damvopoulou E, Parcharidis GE, Louridas GE. Sex-related differences in the angiographic results of 14,500 cases referred for suspected coronary artery disease. Coron Artery Dis. 2008,19:9-14. (PDF)
  7. Chatzizisis YS, Giannoglou GD, Sianos G, Ziakas A, Tsikaderis D, Dardas P, Matakos A, Basdekidou C, Misirli G, Zamboulis C, Louridas GE, Parcharidis GE. In vivo comparative study of linear versus geometrically correct three-dimensional reconstruction of coronary arteries. Am J Cardiol. 2008,101:263-267. (PDF)
  8. Giannoglou GD, Chatzizisis YS, Zamboulis C, Parcharidis GE, Mikhailidis DP, Louridas GE. Elevated heart rate and atherosclerosis: an overview of the pathogenetic mechanisms. Int J Cardiol. 2008,126:302-312. (PDF)
  9. Soulis JV, Giannoglou GD, Chatzizisis YS, Seralidou KV, Parcharidis GE, Louridas GE. Non-Newtonian models for molecular viscosity and wall shear stress in a 3D reconstructed human left coronary artery. Med Eng Phys. 2008,30:9-19. (PDF
  10. Chatzizisis YS. Ask the doctor. Why don't you ever tell your readers that everyone who takes a statin to lower cholesterol should be taking coenzyme Q(10) too? Harv Heart Lett. 2008,19:8. (PDF)


  1. Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Stone PH, Feldman CL. Risk stratification of individual coronary lesions using local endothelial shear stress: a new paradigm for managing coronary artery disease. Curr Opin Cardiol. 2007,22:552-564. (PDF)
  2. Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J Am Coll Cardiol. 2007,49:2379-2393. (PDF)
  3. Chatzizisis YS, Giannoglou GD, Parcharidis GE, Louridas GE. Is left coronary system more susceptible to atherosclerosis than right? A pathophysiological insight. Int J Cardiol. 2007,116:7-13. (PDF)
  4. Chatzizisis YS, Giannoglou GD. Coronary hemodynamics and atherosclerotic wall stiffness: a vicious cycle. Med Hypotheses. 2007,69:349-355. (PDF)
  5. Giannoglou GD, Chatzizisis YS, Misirli G. The syndrome of rhabdomyolysis: Pathophysiology and diagnosis. Eur J Intern Med. 2007,18:90-100. (PDF)
  6. Giannoglou GD, Chatzizisis YS, Koutkias V, Kompatsiaris I, Papadogiorgaki M, Mezaris V, Parissi E, Diamantopoulos P, Strintzis MG, Maglaveras N, Parcharidis GE, Louridas GE. A novel active contour model for fully automated segmentation of intravascular ultrasound images: in vivo validation in human coronary arteries. Comput Biol Med. 2007,37:1292-1302. (PDF)
  7. Papadogiorgaki M, Mezaris V, Chatzizisis YS, Giannoglou GD, Kompatsiaris I. Texture Analysis and Radial Basis Function Approximation for IVUS Image Segmentation. Open Biomed Eng J. 2007,1:53-59. (PDF)


  1. Giannoglou GD, Chatzizisis YS, Sianos G, Tsikaderis D, Matakos A, Koutkias V, Diamantopoulos P, Maglaveras N, Parcharidis GE, Louridas GE. Integration of multi-modality imaging for accurate 3D reconstruction of human coronary arteries in vivo. Nucl Instr Meth Phys Res A. 2006,569:310-313. (PDF)
  2. Giannoglou GD, Antoniadis AP, Chatzizisis YS, Damvopoulou E, Parcharidis GE, Louridas GE. Prevalence of narrowing >or=50% of the left main coronary artery among 17,300 patients having coronary angiography. Am J Cardiol. 2006,98:1202-1205. (PDF)
  3. Giannoglou G, Giannakoulas G, Soulis J, Chatzizisis Y, Perdikides T, Melas N, Parcharidis G, Louridas G. Predicting the risk of rupture of abdominal aortic aneurysms by utilizing various geometrical parameters: revisiting the diameter criterion. Angiology. 2006,57:487-494. (PDF)
  4. Chatzizisis YS, Giannoglou GD, Matakos A, Basdekidou C, Sianos G, Panagiotou A, Dimakis C, Parcharidis GE, Louridas GE. In-vivo accuracy of geometrically correct three-dimensional reconstruction of human coronary arteries: is it influenced by certain parameters? Coron Artery Dis. 2006,17:545-551. (PDF)
  5. Giannoglou GD, Chatzizisis YS, Sianos G, Tsikaderis D, Matakos A, Koutkias V, Diamantopoulos P, Maglaveras N, Parcharidis GE, Louridas GE. In-vivo validation of spatially correct three-dimensional reconstruction of human coronary arteries by integrating intravascular ultrasound and biplane angiography. Coron Artery Dis. 2006,17:533-543. (PDF)
  6. Giannoglou GD, Antoniadis AP, Chatzizisis YS, Damvopoulou E, Parcharidis GE, Louridas GE. Prevalence of ectasia in human coronary arteries in patients in northern Greece referred for coronary angiography. Am J Cardiol. 2006,98:314-318. (PDF)
  7. Soulis JV, Giannoglou GD, Chatzizisis YS, Farmakis TM, Giannakoulas GA, Parcharidis GE, Louridas GE. Spatial and phasic oscillation of non-Newtonian wall shear stress in human left coronary artery bifurcation: an insight to atherogenesis. Coron Artery Dis. 2006,17:351-358. (PDF)
  8. Chatzizisis YS, Giannoglou GD. Pulsatile flow: a critical modulator of the natural history of atherosclerosis. Med Hypotheses. 2006,67:338-340. (PDF)
  9. Tzavella K, Chatzizisis YS, Vakali A, Mandraveli K, Zioutas D,Alexiou-Daniel S. Severe case of Mediterranean spotted fever in Greece with predominantly neurological features. J Med Microbiol. 2006,55:341-343. (PDF)
  10. Soulis JV, Farmakis TM, Giannoglou GD, Chatzizisis YS, Giannakoulas GA, Parcharidis GE, Louridas GE. Molecular viscosity in the normal left coronary arterial tree. Is it related to atherosclerosis? Angiology. 2006,57:33-40. (PDF)