University of Nebraska Medical Center

Murali Ganesan, PhD

Assistant Professor, Division of Gastroenterology and Hepatology


Murali Ganesan, PhD
Dr. Ganesan's focus is in the field of alcoholic liver injury, with special emphasis on "second hits" such as hepatitis B virus, hepatitis C virus, and HIV. His current NIH-K01 grant focus is how alcohol suppresses the HBV peptide-MHC class I presentation on hepatocytes.


  • Effect of Alcohol in HBV peptide-MHC class-1 presentation on hepatocytes
  •  Mechanisms of HIV induced liver injury; Role of Alcohol.
  • Mechanisms of Alcohol and HCV induced liver injury.
Active Grant Support


  • “Ethanol suppresses peptide-MHC class I presentation on HBV
    infected hepatocytes” Principal Investigator, NIH-NIAAA/K01
  • “Extracellular Vesicles As The Vehicles For Promoting Liver Injury
    Induced By HIV And Alcohol” Co-Investigator (Poluektova, Osna), NIH-NIAAA/R01
  • “HBV infection accelerates liver fibrosis development: Role of matrix
    stiffness” Principal Investigator, NU Collaboration Initiative/University of Nebraska Collaboration Initiative/System Science Seed Grant


  • "Alcohol Center Of Research-Nebraska (ACORN)" Other (Casey), DHHS/NIH/NIAAA
  • " Sorting of non-ISGylated HIV proteins to hepatic exosomes promotes liver fibrosis development: role of alcohol" Co-Investigator (Osna), DHHS/NIH/NIAAA
  • BSc: Biochemistry, University of Madras, Chennai, India, 2001
  • MSc: Biochemistry, University of Madras, Chennai, India, 2003
  • PhD: Biochemistry, University of Madras, Chennai, India, 2009