UNMC_Acronym_Vert_sm_4c
University of Nebraska Medical Center

Murali Ganesan, PhD

Assistant Professor, Division of Gastroenterology and Hepatology

402-995-3576

Murali Ganesan, PhD
Dr. Ganesan's focus is in the field of alcoholic liver injury, with special emphasis on "second hits" such as hepatitis B virus, hepatitis C virus, and HIV. His current NIH-K01 grant focus is how alcohol suppresses the HBV peptide-MHC class I presentation on hepatocytes.

Information

Research
  • Effect of Alcohol in HBV peptide-MHC class-1 presentation on hepatocytes
  •  Mechanisms of HIV induced liver injury; Role of Alcohol.
  • Mechanisms of Alcohol and HCV induced liver injury.
Active Grant Support

Active

  • “Ethanol suppresses peptide-MHC class I presentation on HBV
    infected hepatocytes” Principal Investigator, NIH-NIAAA/K01
  • “Extracellular Vesicles As The Vehicles For Promoting Liver Injury
    Induced By HIV And Alcohol” Co-Investigator (Poluektova, Osna), NIH-NIAAA/R01
  • “HBV infection accelerates liver fibrosis development: Role of matrix
    stiffness” Principal Investigator, NU Collaboration Initiative/University of Nebraska Collaboration Initiative/System Science Seed Grant

Pending

  • "Alcohol Center Of Research-Nebraska (ACORN)" Other (Casey), DHHS/NIH/NIAAA
  • " Sorting of non-ISGylated HIV proteins to hepatic exosomes promotes liver fibrosis development: role of alcohol" Co-Investigator (Osna), DHHS/NIH/NIAAA
Education
  • BSc: Biochemistry, University of Madras, Chennai, India, 2001
  • MSc: Biochemistry, University of Madras, Chennai, India, 2003
  • PhD: Biochemistry, University of Madras, Chennai, India, 2009