Publications

Jung, E.M., Moffat, J.J., Liu, J., Dravid, S.M., Gurumurthy, C., Kim, W.Y. (2017) Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior. Nature Neuroscience. In press.

Ka, M., Smith, A.L., Kim, W.Y.  (2017) MTOR controls genesis and autophagy of GABAergic interneurons during brain development. Autophagy. 13 (8): 1348-1363.

Moffat, J.J., Ka, M., Jung, E.M., Smith, A.L., Kim, W.Y.  (2017) The role of MACF1 in nervous system development and maintenance. Seminars in Cell and Developmental Biology. 69: 9-17.

Chen, C, Kim, W.Y., Jiang, P. (2016) Humanized neuronal chimeric mouse brain generated by neonatally engrafted human iPSC2 derived primitive neural progenitor cells. Journal of Clinical Investigation Insight. 1 (19): e88632.

Ka, M., Moffat, J.J., Kim, W.Y. (2016) MACF1 controls migration and positioning of cortical GABAergic interneurons in mice. Cerebral Cortex. In press. (Epub ahead of print).

Ka, M. and Kim, W.Y. (2016) Microtubule-Actin Crosslinking Factor 1 is required for dendritic arborization and axon outgrowth in the developing brain. Molecular Neurobiology. 53 (9): 6018-6032.

Ka, M., Kook, Y., Liao, K., Buch, S., Kim, W.Y. (2016) Transactivation of TrkB by Sigma-1 receptor mediates cocaine-induced changes in dendritic spine density and morphology in hippocampal and cortical neurons. Cell Death & Disease. 7 (10): e2414.

Jung, E.M., Ka, M., Kim, W.Y. (2016) Loss of GSK-3 causes abnormal astrogenesis and behavior in mice. Molecular Neurobiology. 53(6): 3954-3966.

Ka, M., Chopra, D., Dravid, S., Kim, W.Y. (2016) Essential roles for ARID1B in dendritic arborization and spine formation of developing pyramidal neurons. Journal of Neuroscience. 36 (9): 2723-2742.

Jung, E.M., Moffat, J.J., Kim, W.Y. (2015) Regeneration potential of targeting GSK-3 signaling in neural tissues. Neural Regeneration Research. 10 (12): 1912-1913.

Moffat, J.J., Ka, M., Jung, E.M., Kim, W.Y. (2015) Genes and brain malformation associated with abnormal neuron positioning. Molecular Brain. 8: 72.

Kim, W.Y. (2015) Brain size is controlled by the mammalian target of rapamycin (mTOR) in mice. Communicative & Integrative Biology. 8 (1): e994377.

Ka, M., Condorelli, G., Woodgett, J.R., Kim, W.Y. (2014) mTOR regulates brain morphogenesis by mediating GSK-3 signaling. Development. 141: 4076-4086.

Ka., M., Jung, E.M., Mueller, U., Kim, W.Y. (2014) MACF1 regulates the migration of pyramidal neurons via microtubule dynamics and GSK-3 signaling. Developmental Biology. 395: 4-18.

Kim, W.Y.* and Snider W.D. (2011) Functions of GSK-3 signaling in development of the nervous system. Frontiers in Molecular Neuroscience. 4:44. * Corresponding author

Chen Y., Tian X., Kim, W.Y., Snider W.D. (2011) Adenomatous Polyposis Coli Regulates Axon Arborization and Cytoskeleton Organization via Its N-Terminus. PLoS ONE. 6(9): e24335.

Yokota, Y., Eom, T., Stance, A., Kim, W.Y., Rao, S., Snider, W., Anton E.S. (2010). Cdc42 and Gsk3 modulate the dynamics of radial glial growth, inter-radial glial interactions and polarity in the developing cerebral cortex. Development. 137:4101-4110.

Soutar, M.P., Kim, W.Y., Williamson, R., Peggie, M., James Hastie, C., McLauchlan, H., Snider, W.D., Gordon-Weeks, P.R., Sutherland, C. (2010) Evidence that Glycogen Synthase Kinase-3 isoforms have distinct substrate preference in the brain. Journal of Neurochemistry. 115: 974-983.

Kim, W.Y., Wang, X., Wu, Y., Doble, B., Patel, S., Woodgett, J., Snider, W. (2009). GSK-3 is a master regulator of neural progenitor homeostasis in mammals.  Nature Neuroscience. 12:1390-1397.

Yokota, Y., Kim, W.Y., Chen, Y., Wang, X., Komuro, Y., Snider, W., Anton E.S. (2009). The Adenomatous Polyposis Coli (APC) Protein is an Essential Regulator of Radial Glial Polarity and Construction of the Cerebral Cortex. Neuron. 61:42-56. PMCID: PMC2804250.

Kim, W.Y., Gonsiorek, E., Barnhart, C., Davare, M., Engebose, A., Lauridsen, H., Bruun, D., Lesiak, A., Wayman, G., Bucelli, R., Higgins, D., Lein, P. (2009) Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation. Journal of Neurochemistry. 108:1057-1071. PMCID: PMC4277848.

Kim, W.Y., Snider, W. (2008) Neuroscience. Overcoming inhibitions. Science 322:869-72.

Bucelli, R., Gonsiorek, E., Kim, W.Y., Bruun, D., Rabin, R., Higgins, D., Lein, P. (2008) Statins decrease expression of the proinflammatory neuropeptides calcitonin gene-related peptide and substance P in sensory neurons. J Pharmacol Exp Ther. 324:1172-80.

Kim, W.Y., Zhou, F.Q., Zhou, J., Yokota, Y., Wang, Y., Yoshimura, T., Kaibuchi, K., Woodgett, J., Anton, E., Snider, W. (2006) Essential Roles for GSK-3s and GSK-3-Primed Substrates in Neurotrophin-Induced and Hippocampal Axon Growth. Neuron. 52:981-996.

Kim, W.Y., Fayazi, Z., Bao, X., Higgins, D., Kazemi-Esfarjani, P. (2005) Evidence for sequestration of polyglutamine inclusions by Drosophila myeloid leukemia factor. Molecular and Cellular Neuroscience. 29:536-44.

Edelman, A., Kim, W.Y., Higgins, D., Goldstein, E., Oberdoerster, M., Sigurdson, W. (2005) Doublecortin kinase-2, a novel doublecortin-related protein kinase associated with terminal segments of axons and dendrites.  Journal of Biological Chemistry. 280:8531-43.

Kim, W.Y., Horbinski, C., Sigurdson, W., Higgins, D. (2004) Proteasome inhibitors suppress formation of polyglutamine-induced nuclear inclusions in cultured postmitotic neurons.  Journal of Neurochemistry. 91:1044-1056.

Kim, I.J., Drahushuk, K., Kim, W.Y., Gonsiorek, E., Lein, P., Andres, D., Higgins, D. (2004) Extracellular Signal-Regulated Kinases Regulate Dendritic Growth in Rat Sympathetic Neurons.  Journal of Neuroscience. 24:3304-3312.