Sung-Ho Huh, Ph.D.

Sung-Ho Huh, PhDDevelopmental Neuroscience
Huh Lab
Munroe-Meyer Institute
985960 Nebraska Medical Center
Omaha, NE 68198-5960

Phone: 402-559-8291
E-mail


Professional Summary:

I am an Assistant Professor of Developmental Neuroscience in the Munroe-Meyer Institute for Genetics and Rehabilitation and Mary and Dick Holland Regenerative Medicine Program at the University of Nebraska Medical Center. I received postdoctoral training studying inner ear, kidney development and FGF signaling with Dr. Ornitz at the Washington University in St. Louis.

My ultimate goal is to understand mechanisms by which molecular signaling pathways regulate the generation and maintenance of ear and kidney progenitor cells during development and regeneration and use these findings as tools for regenerative medicine.

Three out of 1000 newborns suffer from congenital hearing loss. Age, noise, and antibiotic-mediated hearing loss is due to outer hair cell loss in the cochlea of the inner ear, and these damaged cells are not replaced. In addition, acute and chronic renal diseases are a medical and financial burden in developed countries. The best strategy to repair damaged organs is regeneration through cell-based therapies. The tools and discoveries that my lab will develop through the identification of cochlear and nephron progenitor cell formation can be utilized in the development of new therapies. I believe that selective reactivation of signaling pathways that function during embryonic development may be an effective means to promote repair and regeneration of malformed or damaged organs such as cochlea and kidney, and also prevent pathological responses that could further compromise hearing and kidney function. Thus, a thorough understanding of signaling pathways that are necessary for normal development of the inner ear and kidney is necessary to facilitate the design of treatments for congenital and acquired hearing loss and kidney failure.

Education:

Ph.D., Molecular Cell Biology, Washington University, St. Louis, 2009
M.S., Biochemistry, Korea University, Seoul, Korea, 2001
B.S., Genetic Engineering, Korea University, Seoul, Korea, 1999

Research Interests and Projects:

Research Interests

Current Projects

Publications from PubMed

Professional Affiliations:

Awards

K99/R00 NIH Pathway to Independence