Fluorescence in situ hybridization (FISH) in oncology is used to detect amplifications, deletions, duplications, rearrangements, and/or translocations of chromosome material known to be associated with specific types of cancer.
- FISH testing is offered for both Hematology/Oncology/Lymphoma and Solid Tumor indications.
- FISH testing can be ordered by probe or panel.
- Targeted approach based on differential diagnosis
- Detection includes numerical and structural chromosomal aberrations of interest with diagnostic and prognostic significance
- Monitors response to therapy
- Useful for opposite sex transplant
- Allows for rapid assessment
- Testing available on fresh or fixed tissue
- Targeted assay that provides information about the region(s) of interest only
- Detection dependent on the location and size of the aberration relative to the probe
- Limited resolution as compared to newer technologies such as microarray