There has been significant progress in the care for infants with congenital heart disease in recent years. Thus, longer follow-up periods to address neurodevelopmental needs, such as learning, behavior, attention, and social competence, into later childhood is warranted. The Munroe-Meyer Institute at the University of Nebraska Medical Center has initiated a cardiovascular follow-up clinic to evaluate and study preschool and school-age children who have undergone surgery for complex congenital heart disease. The purpose of this clinic is to further examine developmental outcomes in children with complex congenital heart disease who have undergone corrective surgery. Specifically, neurodevelopmental outcomes are examined longitudinally to further explore the impact of surgical intervention on outcomes for this population at significant risk for developmental disabilities during early and late elementary school. This research will help to address the needs of this population throughout childhood and will facilitate the early identification of developmental impairments so that therapeutic interventions may be initiated to maximize the functional potential of these children.