Investigator-Initiated Peer-Reviewed Research Grants

In addition to partnering with pharmaceutical companies to bring the latest clinical research studies to our patients, our faculty are actively engaged in investigator-initiated peer-reviewed research in order to advance knowledge and improve care for neurological disease.  Our physicians and scientists are the initiators and principal investigators of the following research grants.

Award Year(s): 2021 - 2026, 2016 - 2020
Principal Investigator: Matthew Rizzo, MD
Funding Source: National Institutes of Health (NIH U54GM115458)
Title: Great Plains IDeA-CTR

Award Year(s): 2020 - 2025, 1999 - 2020
Principal Investigator: Matthew Rizzo, MD
Funding Source: National Institutes of Health (NIH R01AG017177)
Title: Monitoring Real-world Driver Behavior for Classification and Early Prediction of Alzheimer’s Disease

Award Year(s): 2017 - 2022, 2000 - 2016
Principal Investigator: Howard Fox, MD, PhD
Funding Source: National Institutes of Health (NIH P30MH062261)
Title: Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center

Award Year(s): 2021 - 2023
Principal Investigator: Anna Dunaevsky, PhD
Funding Source: National Institutes of Health (NIH R21NS122157)
Title: Developing an Astroglial Model for Fragile X Syndrome

Award Year(s): 2021 - 2023
Principal Investigator: Howard Fox, MD, PhD
Funding Source: National Institutes of Health (NIH R21MH128057)
Title: Macrophages and Microglia, Gene Expression and Chromatin: Illuminating the Myeloid Viral Reservoir in the Brain through Single Cell Analyses

Award Year(s): 2021 - 2026
Principal Investigator: Howard Fox, MD, PhD
Funding Source: National Institutes of Health (NIH U01DA053624)
Title: Uncovering HIV/Opioid Effects in the Brain at the Single Cell Level:  Transcription, Chromatin Accessibility, and Reservoir Analysis in the SIV/cART/Morphine/Rhesus Monkey Model

Award Year(s): 2021 - 2024
Principal Investigator: Padmashri Ragunathan, PhD
Funding Source: Creighton University
Title: Translational Hearing Center

Award Year(s): 2021 - 2022
Principal Investigator: Olga Taraschenko, MD, PhD
Funding Source: National Institutes of Health (NIH P20GM130447)
Title: Cognitive Neuroscience of Development and Aging (CoNDA) Center: The Role of Hippocampal Neurogenesis in the Development of Cognitive Deficits in Autoimmune Encephalitis with Seizures

Award Year(s): 2021
Principal Investigator: Amy Hellman, MD
Funding Source: Huntington's Disease Society of America
Title: Huntington's Disease Society of America

Award Year(s): 2021 - 2022
Principal Investigator: Kelly Stauch, PhD
Funding Source: The Michael J. Fox Foundation for Parkinson’s Research
Title: Determining PINK1 and PRKN Enzyme Activities in vivo

Award Year(s): 2021
Principal Investigator: Kelly Stauch, PhD
Funding Source: Nebraska Bankers Association
Title: Seahorse Core Equipment Grant

Award Year(s): 2021
Principal Investigator: Joseph Americo Fernandes, MD
Funding Source: Massachusetts General Hospital
Title: Regimen-Specific Appendix D for Pridopidine Double=Blind Phase

Award Year(s): 2020 - 2025
Principal Investigator: Anna Dunaevsky, PhD
Funding Source: National Institutes of Health (NIH P20GM130447)
Title: Cognitive Neuroscience of Development and Aging (CoNDA) Center

Award Year(s): 2020 - 2022
Principal Investigator: Howard Fox, MD, PhD
Funding Source: National Institutes of Health (NIH R01DA043164)
Title: The Brain as a SIV Reservoir under Suppressive cART Potentiation by Drugs of Abuse

Award Year(s): 2020 - 2024
Principal Investigator: Rana Zabad, MD
Funding Source: Johns Hopkins University
Title: Traditional Versus Early Aggressive Therapy For Multiple Sclerosis (TREAT-MS) Trial

Award Year(s): 2020 - 2025
Principal Investigator: David Warren, PhD
Funding Source: National Institutes of Health (NIH P20GM130447)
Title: Cognitive Neuroscience of Development and Aging (CoNDA) Center - Neuroimaging Core

Award Year(s): 2020 - 2025
Principal Investigator: Kelly Stauch, PhD
Funding Source: National Institutes of Health (NIH P20GM130447)
Title: Cognitive Neuroscience of Development and Aging (CoNDA) Center - Project 5

Award Year(s): 2020 - 2024
Principal Investigator: Pierre Fayad, MD
Funding Source: University of Cincinnati
Title: Anticoagulation in Intracerebral Hemorrhage (ICH) Survivors for Stroke and Recovery (ASPIRE)

Award Year(s): 2020 - 2022
Principal Investigator: Joseph Americo Fernandes, MD
Funding Source: Columbia University
Title: PLS Natural History Study

Award Year(s): 2020 - 2022
Principal Investigator: Olga Taraschenko, MD, PhD
Funding Source: Yale University
Title: New Onset Refractory Status Epilepticus (NORSE)

Award Year(s): 2019 - 2022
Principal Investigator: Matthew Rizzo, MD
Funding Source: Iowa State University
Title: Deep Insight: Deep Extraction of Driver State from Naturalistic Driving Dataset

Award Year(s): 2019 -2023
Principal Investigator: Anna Dunaevsky, PhD
Funding Source:  National Institutes of Health (NIH R01NS109381)
Title: The Role of Astrocytes in the Fragile X Syndrome Pathogenesis

Award Year(s): 2019 - 2023, 2013 - 2018
Principal Investigator: Howard Fox, MD, PhD
Funding Source: National Institutes of Health (NIH U24MH100925)
Title: NNTC Data Coordinating Center

Award Year(s): 2019 - 2024
Principal Investigator: David Warren, PhD
Funding Source: National Institutes of Health (NIH R01AG064247)
Title: Measuring Neurodevelopmental Effects of Polygenic Risk for Alzheimer's Disease via Longitudinal Study of Brain and Cognitive Variables in Periadolescent Children

Award Year(s): 2019 - 2022
Principal Investigator: Kelly Stauch, PhD
Funding Source: US Army W81XWH1910698
Title: Impact of Traumatic Brain Injury on Tauopathy-Induced Synaptotoxicity: Implication for Alzheimer's Disease and Related Dementias

Award Year(s): 2019 - 2024
Principal Investigator: Pierre Fayad, MD
Funding Source: University of Cincinnati
Title: ARCADIA-CSI (Cognition and Silent Infarcts) "Study"

Award Year(s): 2018 - 2023
Principal Investigator: Kelly Stauch, PhD
Funding Source: National Institutes of Health (NIH R01AG059785)
Title: Mechanisms of Presynaptic Energetic Failure Due to Age-Related Pathologic Tau

Award Year(s): 2018 - 2024
Principal Investigator: Pierre Fayad, MD
Funding Source: University of Cincinnati
Title: Sleep for Stroke Management and Recovery Trial (Sleep SMART) Stroke Trial

Award Year(s): 2018 - 2021
Principal Investigator: Howard Fox, MD, PhD
Funding Source: The Michael J. Fox Foundation for Parkinson’s Research
Title: Parkin as a Protective Strategy Against Mitochondrial DNA Stress

Award Year(s): 2018 - 2023
Principal Investigator: Howard Fox, MD, PhD
Funding Source: National Institutes of Health (NIH R01DA047828)
Title: Signatures of Cannabis Abuse in NeuroHIV (SCAN): An Integrated Molecular and Imaging Approach

Award Year(s): 2018 - 2022
Principal Investigator: Padmashri Ragunathan, PhD
Funding Source: National Institutes of Health (NIH R21AA025751)
Title: Effects of Developmental Alcohol Exposure on Astrocyte Ca2+ Signaling and Structural Synaptic Plasticity

Award Year(s): 2017 - 2023
Principal Investigator: Pierre Fayad, MD
Funding Source: University of Cincinnati
Title: AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke (ARCADIA) Study

Award Year(s): 2016 - 2021
Principal Investigator: Daniel Murman, MD
Funding Source:  University of Southern California
Title: Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4 Study)

Award Year(s): 2016 - 2021
Principal Investigator: Amy Hellman, MD
Funding Source: CHDI Foundation
Title: A Prospective Registry Study in a Global Huntington’s Disease Cohort

Award Year(s): 2015 - 2021
Principal Investigator: Daniel Murman, MD
Funding Source: University of Southern California
Title: Longitudinal Evaluation of Amyloid Risk and Neurodegeneration - the LEARN Study A companion observation study to Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Trial