Investigator-Initiated Peer-Reviewed Research Grants


*Some of the steering committee members of the Great Plains IDeA-CTR Network include: (left-right) Ted Mikuls, MD, Ann Fruhling, PhD, Ashok Mudgapalli, PhD, Fang Yu, PhD, Jim McClay, MD, Matt Rizzo, MD (Principal Investigator), Mary Cramer, PhD, Shinobu Watanabe-Galloway, PhD, Risto Rautiainen, PhD, Howard Fox, MD, PhD, and Karla Klaus.  NOTE: Dr. Fruhling is from the University of Nebraska at Omaha.  All others in the photo are from UNMC.  Those UNMC steering committee members missing from the photo are: Paul Estabrooks, Phd, Lani (Chi Chi) Zimmerman, PhD, Jane Meza, PhD, and Babu Guda, PhD.

In addition to partnering with pharmaceutical companies to bring the latest clinical research studies to our patients, our faculty are actively engaged in investigator-initiated peer-reviewed research in order to advance knowledge and improve care for neurological disease.  Our physicians and scientists are the initiators and principal investigators of the following research grants.

Award Year(s): 2016 - 2021
Principal Investigator: Matthew Rizzo, MD
Funding Source: National Institutes of Health (NIH U54 GM115458)
Title: Great Plains IDeA-CTR

Award Year(s): 2016 - 2019
Principal Investigator:
Tony W. Wilson, PhD (Co-Principal Investigator)
Funding Source:  American Heart Association AHA Collaborative Sciences Award
Title: Exploring the Neurological Basis of Dyspnea and its Impact on Exercise Intolerance in Heart Failure

Award Year(s): 2016 - 2018
Principal Investigator:
Tony W. Wilson, PhD
Funding Source:
  National Institutes of Health (NIH R03 DA041917)
Title: The Impact of Marijuana Use on Brain and Cognitive Function in HIV-Infected Patients

Award Year(s): 2016 – 2017
Principal Investigator: David E. Warren, PhD
Funding Source: Nebraska EPSCoR
Title:
Transcranial Magnetic Stimulation (TMS) to Support Novel Neuroscience Research in Nebraska

Award Year(s): 2016 – 2017
Principal Investigator: David E. Warren, PhD
Funding Source: The Fremont Area Alzheimer's Fund
Title: Using Neuroimaging and Neurostimulation to Understand and Improve Cognition in Alzheimer's Disease

Award Year(s): 2015 – 2019
Principal Investigator: Tony W. Wilson, PhD (Co-Principal Investigator)
Funding Source: National Science Foundation (Cooperative Agreement 1539067)
Title: RII Track-2 FEC: Developmental Chronnecto-Genomics (Dev-CoG): A Next Generation Framework for Quantifying Brain Dynamics and Related Genetic Factors in Childhood

Award Year(s): 2015 – 2019
Principal Investigator: Tony W. Wilson, PhD
Funding Source: National Institutes of Health (NIH R01 MH103220-02S1)
Title: Sex Differences in the Neuronal Markers of HAND and the Impact of Aging (supplementary grant to support statistical testing for gender differences in healthy aging)

Award Year(s): 2015 – 2019
Principal Investigator: Tony W. Wilson, PhD
Funding Source: National institutes of Health (NIH R01 MH103220-02S2)
Title: Linking Molecular Markers of Aging, the Epigenome, and Functional Neuroimaging (supplement to support epigenetic analyses)

Award Year(s):  2015 – 2018
Principal Investigator: Deepak Madhavan, MD
Funding Source:  State of Nebraska
Title: Safety and Tolerability of Cannabidiol (CBD) in Subjects with Drug Resistant Epilepsy

Award Year(s): 2015 – 2017
Principal Investigator: Pariwat Thaisetthawatkul, MD
Funding Source:  University of Kansas
Title: Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (Pain Controls)

Award Year(s): 2015 – 2017
Principal Investigator: Tony W. Wilson, PhD
Funding Source: University of Nebraska Foundation Shoemaker Prize for Neurodegenerative Research
Title: Using Noninvasive Brain Stimulation to Normalize Neural Networks and Reduce Cognitive Impairment in Humans

Award Year(s): 2015 – 2016
Principal Investigator: Sachin Kedar, MD
Funding Source:  University of Nebraska
Title: Changes in Position of the Lamina Cribrosa in Patients Undergoing Lumbar Puncture

Award Year(s): 2015 – 2016
Principal Investigator: Sachin Kedar, MD
Funding Source:  Fremont Area Alzheimer’s Committee
Title: Retinal Imaging: A Window on Mind and Brain Health and Alzheimer’s Disease

Award Year(s): 2015 – 2016
Principal Investigator: Pariwat Thaisetthawatkul, MD
Funding Source:  University of Nebraska
Title: Differentiating parameters for an inflammatory neuropathy in diabetic patients

Award Year(s): 2015 – 2016
Principal Investigator: Tony W. Wilson, PhD
Funding Source: Nebraska Bankers Association Bankers Equipment Grant Program
Title: High-Definition Human Brain Stimulation in Nebraska: Building Key Infrastructure for the Next Frontier in Neuroscience

Award Year(s):  2015
Principal Investigator: Amy Hellman, MD
Funding Source:  University of Nebraska Foundation Parkinson’s Disease Skate-A-Thon Grant
Title: Optimizing Gait Variability in Parkinson’s Disease with a Structured Auditory Stimulus

Award Year(s): 2014 – 2019
Principal Investigator: Tony W. Wilson, PhD
Funding Source: National Institutes of Health (NIH R01 MH103220)
Title: Neurophysiological Markers of HAND and the Impact of Aging: Evidence from MEG

Award Year(s): 2014 - 2017
Principal Investigator: Matthew Rizzo, MD
Funding Source: Toyota Motor, Inc.
Title: Measuring and Mitigating Unintended Acceleration in Younger and Older Drivers

Award Year(s): 2013 – 2018; 2006 – 2012; 1999 – 2005
Principal Investigator: Matthew Rizzo, MD
Funding Source: National Institutes of Health (NIH R01 AG017177)
Title: Predictions of Driver Safety in Advancing Age

Award Year(s): 2013 – 2014 
Principal Investigator: Tony W. Wilson, PhD
Funding Source: University of Nebraska Foundation Oldfield Award
Title: Neurophysiology of HIV-Associated Neurocognitive Disorders

Award Year(s): 2013 – 2014
Principal Investigator: Tony W. Wilson, PhD
Funding Source: University of Nebraska Foundation Parkinson’s Disease Skate-A-Thon Grant
Title: Motor Deficits are Modulated by Movement Parameters in PD

Award Year(s): 2013
Principal Investigator: Matthew Rizzo, MD
Funding Source: American Academy of Neurology
Title: Moral Practice Under Accountable Care Organizations

Award Year(s): 2012 – 2015
Principal Investigator: Matthew Rizzo, MD
Funding Source: Toyota Motor Engineering of North America, Inc.
Title: Measuring Use and Impact of In-Vehicle Technologies on Older Drivers

Award Year(s):  2012 – 2014
Principal Investigator: John Bertoni, MD
Funding Source:  Creighton University
Title: Differentiation of Central versus Peripheral Fatigue in Parkinson’s Disease

Award Year(s): 2012 – 2013
Principal Investigator: Tony W. Wilson, PhD
Funding Source:  Nebraska Bankers Association Bankers Equipment Grant Program
Title: Improved Neuro-Computing Resources for the Center for Magnetoencephalography

Award Year(s): 2012
Principal Investigator: Amy Hellman, MD
Funding Source:  Parkinson’s Disease Research, Education, and Clinical Centers Home (PADRECC)
Title: Continuous Non-Invasive Arterial Pressure Monitoring to Detect Autonomic Dysfunction in Parkinson’s Disease

Award Year(s): 2011 – 2012
Principal Investigator: Pariwat Thaisetthawatkul, MD
Funding Source: University of Nebraska
Title: Utility of Diagnostic Methods for Small Fiber Neuropathy

Award Year(s): 2010 – 2015
Principal Investigator: Matthew Rizzo, MD
Funding Source:  National Institutes of Health (NIH R01 HL091917)
Title: PAP Adherence and Real-World Driving Safety in OSA

Award Year(s): 2010 – 2013
Principal Investigator: Matthew Rizzo, MD
Funding Source:  Nissan Motor C, Ltd.
Title: Nissan UI Collaborative Research (NRC)

Award Year(s): 2010 – 2012
Principal Investigator: Matthew Rizzo, MD
Funding Source:  Centers for Disease Control (CDC CE001167)
Title: Driving Safety and Real-Time Glucose Monitoring in Type 1 Insulin-Dependent Diabetes

Award Year(s): 2010 – 2012
Principal Investigator: Matthew Rizzo, MD
Funding Source:  Iowa Department of Transportation
Title: Diagnostic Tools for Identifying Sleepy Drivers in the Field

Award Year(s):  2010 - 2011
Principal Investigator:  Diego Torres-Russotto, MD (Co-Principal Investigator)
Funding Source:  University of Nebraska Foundation Shoemaker Prize
Title: T-Cell Subsets in Parkinson’s Disease

Award Year(s):  2010 – 2011
Principal Investigator: Pariwat Thaisetthawatkul, MD
Funding Source: University of Nebraska
Title: Vitamin D Deficiency in Patients with Painful Sensory Neuropathy

Award Year(s):  2010 – 2011
Principal Investigator: Matthew Rizzo, MD
Funding Source: Nissan Motor Co., Ltd.
Title: Nissan UI Collaborative Research (NTCNA)

Award Year(s): 2007 - 2009
Principal Investigator: Matthew Rizzo, MD
Funding Source:  Army Research Laboratory (Contract DAAD19-01-2-0009)
Title: Translational Neuroscience: Bringing Neuroscience to the Soldier’s Operational Environment

Award Year(s): 2007 - 2008
Principal Investigator: Matthew Rizzo, MD
Funding Source:  Nintendo
Title: Gaming and Cognition

Award Year(s): 2006 - 2011
Principal Investigator: Matthew Rizzo, MD
Funding Source:  National Institutes of Health (NIH R01 AG026027)
Title: In-Car Technology to Alert Attention Impaired Drivers

Award Year(s): 2006 – 2008
Principal Investigator: Matthew Rizzo, MD (Co-Principal Investigator)
Funding Source: Centers for Disease Control (R49/CCR 721682)
Title: Effects of Phenytoin on Driving Safety

Award Year(s): 2006 – 2007
Principal Investigator: Tony W. Wilson, PhD
Funding Source: National Institutes of Health (NIH F32 MH078359)
Title: Sensorimotor Interactions in Childhood Schizophrenia

Award Year(s): 2006
Principal Investigator: Tony W. Wilson, PhD
Funding Source:  University of Colorado Health Sciences Center DPEF Seed Grant
Title: Sensorimotor Interactions in Children with Schizophrenia

Award Year(s): 2005 – 2010
Principal Investigator: Matthew Rizzo, MD (Co-Principal Investigator)
Funding Source:  National Institutes of Health (NIH R01 DA17341)
Title: Residual Effects of Ecstasy on Decision-Making and Driving

Award Year(s): 2005 – 2008
Principal Investigator: Tony W. Wilson, PhD
Funding Source:  National Institutes of Health (NIH F32 MH078359)
Title: Sensorimotor Interactions in Childhood Schizophrenia

Award Year(s):  2004 – 2007
Principal Investigator: Daniel L. Murman, MD
Funding Source: Alzheimer’s Association, Senator Mark Hatfield Award for Clinical Research in Alzheimer’s Disease
Title: Quality Indicators in Ambulatory Dementia Care

Award Year(s): 2004 – 2007
Principal Investigator: Daniel L. Murman, MD
Funding Source:  Nebraska Tobacco Settlement Biomedical Research Development Fund
Title: Enhancing Clinical Research in Dementia and Translating Advances into Clinical Practice

Award Year(s): 2004 – 2005
Principal Investigator: Sachin Kedar, MD
Funding Source:  Research for the Prevention of Blindness
Title: A Study of Clinical and Natural Course of Homonymous Hemianopia

Award Year(s): 2003 – 2010
Principal Investigator: Matthew Rizzo, MD (Co-Principal Investigator)
Funding Source:  National Institutes of Health (NIH R01 NS044930)
Title: Predicting Driver Safety in Parkinson’s Disease

Award Year(s):  2000 – 2002
Principal Investigator: Daniel L. Murman, MD
Funding Source:  Michigan State University Foundation
Title: Genetic Predictors of Psychosis in Alzheimer’s Disease

Award Year(s): 1999 – 2006
Principal Investigator: Matthew Rizzo, MD
Funding Source:  National Institutes of Health (NIA R01 AG NS15071)
Title: Safe and Unsafe Driving in Old Age, Alzheimer’s Disease, and Stroke

Award Year(s): 1999 – 2004
Principal Investigator: Daniel L. Murman, MD
Funding Source:  National Institutes of Health (NIH K08 AG000864-05)
Title: Predictors of Direct Costs in Alzheimer’s Disease

Award Year(s): 1999 – 2004
Principal Investigator: Matthew Rizzo, MD
Funding Source:  National Institutes of Health (NIA R01 AG17177)
Title: Predictions of Driver Safety in Advancing Age

Award Year(s): 1999 – 2000
Principal Investigator: Daniel L. Murman, MD
Funding Source:  National Institute on Aging / Michigan Alzheimer’s Disease Research Center
Title: Measuring Determinants of Cost in Dementia Patients

Award Year(s):  1999
Principal Investigator: Daniel L. Murman, MD (Co-Principal Investigator)
Funding Source:  Michigan Public Health Institute Grant
Title: Michigan Dementia Postmortem Network Project

Award Year(s):  1996 – 1999
Principal Investigator: Matthew Rizzo, MD
Funding Source:  Centers for Disease Control (CDC R49/CCR 703640)
Title: Driving After Head Injury

Award Year(s):  1996 – 1999
Principal Investigator: Matthew Rizzo, MD
Funding Source:  Centers for Disease Control (CDC R49/CCR 710136)
Title: Driving Ability and Car Crashes in Old Age and Dementia

Award Year(s):  1994 – 1995 
Principal Investigator: Matthew Rizzo, MD
Funding Source:  Centers for Disease Control (CDC R49/CCR 703640)
Title: High Fidelity Driving Simulation

Award Year(s):  1985 - 1986
Principal Investigator: Matthew Rizzo, MD
Funding Source:  National Institutes of Health (NIH RR 05372)
Title: Biomedical Research Support Grant