{"id":110219,"date":"2024-05-08T16:10:20","date_gmt":"2024-05-08T21:10:20","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/?p=110219"},"modified":"2024-05-09T13:06:35","modified_gmt":"2024-05-09T18:06:35","slug":"medical-research-highlights-may-2024","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2024\/05\/08\/medical-research-highlights-may-2024\/","title":{"rendered":"Medical research highlights, May 2024"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p>The UNMC College of Medicine received grant&nbsp;and funding awards representing nearly $3 million in new funding in March. Awards included:<\/p>\n\n\n\n<p><strong>Sujata Chaudhari, PhD,<\/strong>\u00a0pathology, microbiology and immunology, received a grant of $1,229,964 from NSF for the study \u201cUnderstanding the Molecular Mechanisms of Insect Cuticular Chitin Maintenance.\u201d<\/p>\n\n\n\n<p><strong>Sunyoung Kim, PhD,<\/strong>&nbsp;surgery-cardiothoracic surgery, received a grant of $143,764 from the American Heart Association for the study \u201cAlcohol and Notch Pathway Mutations Synergistically Induce Atrioventricular Canal Defects: Potential Rescue by Folate.\u201d<\/p>\n\n\n\n<p><strong>Iraklis Pipinos, MD,<\/strong>&nbsp;surgery-vascular surgery, received a grant of $131,384 from the University of Nebraska at Omaha for the Center for Cardiovascular Research in Biomechanics.<\/p>\n\n\n\n<p><strong>Austin Wheeler, MD,<\/strong>&nbsp;internal medicine-rheumatology, received a grant of $125,000 from the Rheumatology Research Foundation for work on the development of a comprehensive risk score for rheumatoid arthritis-associated interstitial lung disease and progression.<\/p>\n\n\n\n<p><strong>Seema Singh, PhD, <\/strong>pharmacology and experimental neuroscience, received a grant of $76,750 from DHHS\/NIH\/NIAA for the study \u201cHIV Tat and alcohol-mediated activation of astrocytes involves ER stress\/NLRP6 inflammasome axis.\u201d<\/p>\n\n\n\n<p><strong>Steve Gliske, PhD, <\/strong>neurosurgery, received a grant of $412,862 from the University of Michigan for a study characterizing High-frequency oscillations as an epilepsy biomarker with big data tools.<\/p>\n\n\n\n<p><strong>Shibiao Wan, PhD, <\/strong>genetics, cell biology and anatomy, received a grant of $25,000 from Nebraska EPSCoR for \u201cA Unified Machine Learning Framework to Integrate Large-Scale Single Cell and Bulk Multi-Omics Data for Cancer Subtyping.\u201d<\/p>\n\n\n\n<p><strong>Bryant England, MD, PhD,<\/strong>&nbsp;internal medicine-rheumatology, received a grant of $16,380 from the University of Pennsylvania School of Medicine for a study of genetic predictors of metabolic adverse effects with glucocorticoid treatment in patients with rheumatoid arthritis.<\/p>\n\n\n\n<p><strong>Scott Lundgren, DO,<\/strong>&nbsp;internal medicine-cardiovascular, received a grant of $16,000 from Tufts Medical Center for the Pulmonary Artery Catheter in Cardiogenic Shock Trial.<\/p>\n\n\n\n<p><strong>Prasanth Ravipati, MD,<\/strong>&nbsp;internal medicine-nephrology, received a grant of $1,000 from Benaroya Research Institute at Virginia Mason for a study on the efficacy of Belimumab and Rituximab compared to Rituximab alone for the treatment of primary membranous nephropathy.<\/p>\n\n\n\n<p><strong>Industry-sponsored grants and contracts:<\/strong><\/p>\n\n\n\n<p>The following industry-sponsored grants and contracts were received.<\/p>\n\n\n\n<p><strong>Cyrus Desouza, MBBS,<\/strong>&nbsp;internal medicine-DEM, received funding for a study to evaluate the effect of inclisiran on preventing major adverse cardiovascular events in high-risk primary prevention patients.<\/p>\n\n\n\n<p><strong>Scott Westphal, MD,<\/strong>&nbsp;internal medicine-nephrology, received funding for a study evaluating the safety and efficacy of Tegoprubart in patients undergoing kKidney transplantation.<\/p>\n\n\n\n<p><strong>Pukhraj Rishi, MBBS,<\/strong>&nbsp;ophthalmology and visual sciences, received funding for a trial to evaluate efficacy and safety of belzupacap sarotalocan (AU-011) treatment compared to sham control in subjects with primary indeterminate lesions or small choroidal melanoma.<\/p>\n\n\n\n<p><strong>Soonjo Hwang, MD,<\/strong>&nbsp;psychiatry, received funding for a study of OLZ\/SAM vs. Olanzapine to evaluate weight gain as assessed by change in BMI Z-score in pediatric subjects with schizophrenia or bipolar I disorder.<\/p>\n\n\n\n<p><strong>Erin Barrett, MD,<\/strong>&nbsp;dermatology, received funding for a study of patients receiving Dupilumab for prurigo nodularis.<\/p>\n\n\n\n<p><strong>Carlos Gomez, MD,<\/strong>&nbsp;internal medicine-infectious diseases, received funding to evaluate the efficacy and safety of CAL02 administered intravenously in addition to standard of care in subjects with severe community-acquired bacterial pneumonia.<\/p>\n\n\n\n<p><strong>Scott Koepsell, MD, PhD,<\/strong>&nbsp;pathology\/microbiology, received funding for a study of HemosIL CL HIT-IgG(PF4-H) reagents on the ACL TOP 970 CL instrument.<\/p>\n\n\n\n<p><strong>Christopher D\u2019Angelo, MD,<\/strong>&nbsp;internal medicine-oncology\/hematology, received funding for an intermediate-size population expanded access program for cilta-cel out-of specification (OOS) in patients with multiple myeloma.<\/p>\n\n\n\n<p><strong>Hani Haider, PhD,<\/strong>&nbsp;orthopedic surgery, received funding for a work order: Dynamic post fatigue testing of the Optimotion PS Total Knee Replacement System.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The college received grant\u00a0and funding awards representing nearly $3 million in new funding in March. <\/p>\n","protected":false},"author":27,"featured_media":109914,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"21146,93454,70840,70324,66401,37372","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-110219","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","department-intercom","author_override-intercom"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Medical research highlights, May 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