{"id":120853,"date":"2024-11-01T15:37:29","date_gmt":"2024-11-01T20:37:29","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/?p=120853"},"modified":"2025-03-28T16:21:05","modified_gmt":"2025-03-28T21:21:05","slug":"apples-and-oranges","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2024\/11\/01\/apples-and-oranges\/","title":{"rendered":"Apples and Oranges"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p>Zachary Van Roy, an MD\/PhD trainee in the laboratory of Dr. Tammy Kielian, has indeed had a very productive month as he has published two first author manuscripts in Nature Communication and Cell Reports Medicine.&nbsp; The <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11487069\/\">manuscript<\/a> published in Nature Communication established that <em>S. aureus <\/em>biofilm infections elicit distinct immune and metabolic responses depending on their location as unique signatures were noted in craniotomy vs prosthetic joint infections.&nbsp; These data suggest that it will be difficult to identify immune stimulating therapeutics, including vaccines, that have broad acting activity against <em>S. aureus <\/em>as each niche is distinct (apples and oranges, thus the figure as designed by Zach)<em>.<\/em><\/p>\n<a rel=\"nofollow\" href=\"\/secure-location.php\" style=\"display: none;\" title=\" vJE DIcm PYD aaf J  lEt \"> vJE DIcm PYD aaf J  lEt <\/a><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Zachary Van Roy, an MD\/PhD trainee in the laboratory of Dr. Tammy Kielian, has indeed had a very productive month as he has published two first author manuscripts in Nature Communication and Cell Reports Medicine.&nbsp; The manuscript published in Nature Communication established that S. aureus biofilm infections elicit distinct immune and metabolic responses depending on [&hellip;]<\/p>\n","protected":false},"author":147,"featured_media":120857,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[3263],"class_list":["post-120853","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-research","department-pathology-and-microbiology","author_override-paul-fey-phd-unmc-department-of-pathology-microbiology-and-immunology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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