{"id":120874,"date":"2024-11-01T21:35:18","date_gmt":"2024-11-02T02:35:18","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/?p=120874"},"modified":"2025-03-28T16:45:42","modified_gmt":"2025-03-28T21:45:42","slug":"dr-sturd-publishes-a-first-author-manuscript-in-msphere","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2024\/11\/01\/dr-sturd-publishes-a-first-author-manuscript-in-msphere\/","title":{"rendered":"Dr. Sturd publishes a first author manuscript in mSphere"},"content":{"rendered":"
\n

Chlamydia trachomatis <\/em>is a leading cause of sexually transmitted infections worldwide.\u00a0 As an obligate intracellular pathogen, it has been selected to establish a niche within the host cell in a membrane-derived vacuole called the chlamydial inclusion.\u00a0 Chlamydial proteins recruit host proteins to the chlamydial inclusion that are critical for infection development.\u00a0 Two of these host-derived chlamydial inclusion proteins include FLI1 and LRRF1.\u00a0 Dr. Natalie Sturd and her PI and mentor, Dr. Lisa Rucks, identified that the FLI1 and LRRF1 localization was dependent upon the chlamydial effector ct226 and that FLI1 localization was independent of LRRF1 localization.\u00a0 However, FLI1 co-immunoprecipitated with Ct226 but only in the presence of LRRF1 suggesting that these proteins have both independent and overlapping mechanisms for localization.\u00a0Article can be read here<\/a>. Dr. Sturd is current an M3 trainee in the MD\/PhD scholars’ program and defended her dissertation in January of 2024.\u00a0<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

Chlamydia trachomatis is a leading cause of sexually transmitted infections worldwide.\u00a0 As an obligate intracellular pathogen, it has been selected to establish a niche within the host cell in a membrane-derived vacuole called the chlamydial inclusion.\u00a0 Chlamydial proteins recruit host proteins to the chlamydial inclusion that are critical for infection development.\u00a0 Two of these host-derived […]<\/p>\n","protected":false},"author":147,"featured_media":120876,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[3263],"class_list":["post-120874","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-research","department-pathology-and-microbiology","author_override-paul-fey-phd-unmc-department-of-pathology-microbiology-and-immunology"],"yoast_head":"\nDr. Sturd publishes a first author manuscript in mSphere<\/title>\n<meta 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