{"id":121317,"date":"2025-04-09T13:50:31","date_gmt":"2025-04-09T18:50:31","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/?p=121317"},"modified":"2025-04-09T17:36:35","modified_gmt":"2025-04-09T22:36:35","slug":"medical-research-highlights-april-2025","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2025\/04\/09\/medical-research-highlights-april-2025\/","title":{"rendered":"Medical research highlights, April 2025"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\">\n<p>The UNMC College of Medicine recently received grants\u00a0and awards representing nearly $5 million in new funding. Awards included:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Benson Edagwa, PhD,<\/strong>&nbsp;pharmacology and experimental neuroscience, received a grant of $978,661 from the DHHS\/NIH\/NIAID to study dose-flexible, ultra-long-acting prodrug formulations for pediatric populations.<\/li>\n\n\n\n<li><strong>Mabruka Alfaidi, MD, PhD,&nbsp;<\/strong>cellular and integrative physiology, received a grant of $410,370 from the DHHS\/NIH\/NHLBI for a study of IL-1R1 in endothelial-to-mesenchymal activation.<\/li>\n\n\n\n<li><strong>Wasim Nasser, PhD,<\/strong>&nbsp;biochemistry and molecular biology, received a grant of $183,220 from U.S. Army\/USAMRAA\/CDMRP for a study targeting the CCL17\/CCR4 axis to eradicate lung cancer brain metastasis.<\/li>\n\n\n\n<li><strong>Isuzu Meyer, MD,<\/strong>&nbsp;obstetrics\/gynecology, received a grant of $97,567 from Mary Hitchcock Memorial Hospital for a study of reduced dose OnabotulinumtoxinA for urgency urinary incontinence among older women.<\/li>\n\n\n\n<li><strong>Rick Starlin, MD,<\/strong>&nbsp;internal medicine-infectious diseases, received a grant of $60,000 from COPD Foundation for the Bronchiectasis and NTM Care Center Network.<\/li>\n\n\n\n<li><strong>Cyrus Desouza, MBBS,&nbsp;<\/strong>internal medicine-DEM, received a grant of $42,141 from the Nebraska Educational Biomedical Research Foundation as an ICA for Nate Hudnall.<\/li>\n\n\n\n<li><strong>Eleanor Gradidge, MD,<\/strong>&nbsp;pediatrics-critical care, received a grant of $18,618 from Children\u2019s Hospital of Los Angeles for the study \u201cDead Space and Inhaled Nitric Oxide in Pediatric Acute Respiratory Distress Syndrome.\u201d<\/li>\n\n\n\n<li><strong>Santhi Gorantla, PhD,<\/strong>&nbsp;pharmacology and experimental neuroscience, received a grant of $16,885 from the University of Arizona for a study of ionic liquid-based nanoemulsion containing combination antiretroviral drugs for the oral and transdermal treatment of HIV infection.<\/li>\n\n\n\n<li><strong>Jeffrey Salomon, MD,<\/strong>&nbsp;pediatrics-critical care, received a grant of $2,800 from the University of Pennsylvania for the MANTIS study.<\/li>\n<\/ul>\n\n\n\n<p><strong>Industry-sponsored grants and contracts:<\/strong><\/p>\n\n\n\n<p>The following industry-sponsored grants and contracts were received.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mridula Krishnan, MBBS,&nbsp;<\/strong>internal medicine-oncology\/hematology, received funding for a study of the efficacy of AMG 193 in combination with other therapies in subjects with advanced gastrointestinal, biliary tract or pancreatic cancers with homozygous MTAP-deletion.<\/li>\n\n\n\n<li><strong>Apar Ganti, MD,<\/strong>&nbsp;internal medicine-oncology\/hematology, received funding for a dose escalation and dose expansion, safety and tolerability study of onCARlytics (CF33-CD19), administered intravenously or intratumorally in combination with Blinatumomab in adults with advanced or metastatic solid tumors.<\/li>\n\n\n\n<li><strong>Dr. Edagwa <\/strong>also received funding for development of novel prodrugs of central nervous (CNS) and cardiometabolic medicine, and parenteral injectable formulations.<\/li>\n\n\n\n<li><strong>Soonjo Hwang, MD,<\/strong>&nbsp;psychiatry, received funding for a long-term, safety extension study of OLZ\/SAM in pediatric subjects with schizophrenia or bipolar I disorder.<\/li>\n\n\n\n<li><strong>Ronald Zolty, MD, PhD,<\/strong>&nbsp;internal medicine-cardiovascular, received funding for a study evaluating the long-term safety and efficacy of Seralutinib orally inhaled for the treatment of pulmonary arterial hypertension.<\/li>\n\n\n\n<li><strong>Alfred Fisher, MD, PhD,<\/strong>&nbsp;internal medicine-geriatrics, received funding to study a novel platform to facilitate provider adoption of cognitive care planning.<\/li>\n\n\n\n<li><strong>Scott Koepsell, MD, PhD,<\/strong>&nbsp;pathology, microbiology and immunology, received funding for validation of the clinical performance of HemosIL CL Anti-Cardiolipin IgG and HemosIL CL Anti-\u00df2 Glycoprotein-I IgG on the ACL TOP 970 CL Matrix Comparison.<\/li>\n<\/ul>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The UNMC College of Medicine recently received grants\u00a0and awards representing nearly $5 million in new funding.<\/p>\n","protected":false},"author":27,"featured_media":121318,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"26872,42046,103544,34285,43177,44738","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-121317","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Medical research highlights, April 2025<\/title>\n<meta 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