{"id":123344,"date":"2025-06-25T14:15:00","date_gmt":"2025-06-25T19:15:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/?p=123344"},"modified":"2025-07-21T08:50:06","modified_gmt":"2025-07-21T13:50:06","slug":"resident-studies-outcomes-of-neoadjuvant-therapy-for-unmc-breast-cancer-patients","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2025\/06\/25\/resident-studies-outcomes-of-neoadjuvant-therapy-for-unmc-breast-cancer-patients\/","title":{"rendered":"Resident studies outcomes of neoadjuvant therapy for UNMC breast cancer patients"},"content":{"rendered":"
\n

Neoadjuvant, or presurgical, therapy has been an increasingly common treatment for breast cancer patients. And while there have been a number of studies looking at treatment outcomes, they have been narrowly focused. What if someone took a more comprehensive look at patient outcomes?<\/p>\n\n\n\n

That\u2019s exactly what Nila Jones, MD, a second-year anatomic and clinical pathology resident in UNMC\u2019s Department of Pathology, Microbiology and Immunology, aims to do. She plans to use the READi Core to extract from UNMC\u2019s database cancer synoptic reports and treatment data for breast cancer patients who received neoadjuvant therapy at UNMC between 2014 and 2024. With one to three patients receiving this therapy every week at UNMC, Dr. Jones figures to have up to 1,500 patient cases to review.<\/p>\n\n\n\n

\u201cWe want to look at patient outcomes through several lenses,\u201d she said, including relationship of outcome to the characteristics of each patient\u2019s cancer\u2014histological findings, hormone status, molecular subtype, and grade.<\/p>\n\n\n\n

\u201cWe\u2019re looking at different characteristics of each patient’s cancer and making note of how neoadjuvant treatment related to those characteristics and the patient\u2019s outcomes,\u201d she said. \u201cI think what\u2019s special about this type of approach is that it will be more generalized\u2014this is all the cancer we\u2019ve seen, and this is how it all has reacted. In contrast, our literature review led us to many articles focused on one malignant entity or one target.  We\u2019re going to parse through the data, see where connections exist, and determine if they\u2019re significant or not.\u201d<\/p>\n\n\n\n

Dr. Jones’ study is made possible by the department\u2019s Research Grant Awards, created in 2024. The awards provide up to $10,000 in research funding to residents and fellows. The aim of this program is to advance the experience and mentorship in clinical and translational research.\u00a0\u00a0<\/p>\n\n\n\n

The St. Louis native, who earned her MD at the University of Missouri-Kansas City before coming to UNMC for her residency, said her mentor, Dr. Mary Edgerton, suggested the study. \u201cShe had been thinking there had been so much change over the past few decades or so that we really should be reanalyzing everything,\u201d Dr. Jones said.<\/p>\n\n\n\n

They also hope that by using SNOMED coding coupled to College of American Pathologists (CAP) Cancer Protocols, they can create a data set that is interoperable with other institutions around the world using either CAP Cancer Protocols or International Consortium on Cancer Reporting, which has also been mapped to SNOMED.<\/p>\n\n\n\n

Dr. Edgerton added: \u201cWe are very excited both to demonstrate the utility of using the CAP Cancer Protocols to bypass time and tedium of excessive medical record curation, but also to be able to use SNOMED to make the data interoperable. We have already had an abstract on this topic accepted to present in person in an onsite oral presentation in the SNOMED CT Expo 2025 program in Antwerp, Belgium, this coming fall. This is a tremendous achievement for Dr. Jones.\u201d<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

Nila Jones, MD, a second-year resident in UNMC’s Department of Pathology, Microbiology and Immunology, is taking a comprehensive look at patient outcomes of neoadjuvant breast cancer therapy for UNMC patients between 2014 and 2024.<\/p>\n","protected":false},"author":146,"featured_media":123345,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[3603,3604,3263,3580],"class_list":["post-123344","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-breast-cancer","tag-neoadjuvant-therapy","tag-research","tag-residents-and-fellows","department-pathology-and-microbiology","author_override-duane-retzlaff-unmc-department-of-pathology-microbiology-and-immunology"],"yoast_head":"\nResident 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