{"id":123357,"date":"2025-06-27T01:56:00","date_gmt":"2025-06-27T06:56:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/?p=123357"},"modified":"2025-06-26T14:53:55","modified_gmt":"2025-06-26T19:53:55","slug":"ku-medical-center-unmc-to-lead-clinical-trials-center","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2025\/06\/27\/ku-medical-center-unmc-to-lead-clinical-trials-center\/","title":{"rendered":"KU Medical Center, UNMC to lead clinical trials center"},"content":{"rendered":"
\n

The University of Kansas Medical Center has named UNMC its partner in the institution\u2019s five-year, $31 million grant from the National Institutes of Health to coordinate clinical trials for infants and children in rural and underserved areas.<\/p>\n\n\n\n

In partnership with UNMC, KU Medical Center will serve as the Data Coordinating and Operations Center for the Environmental influences on Child Health Outcomes<\/a> Institutional Development Award States Pediatric Clinical Trials Network. The grant, awarded earlier this month, is the largest five-year award in the history of KU Medical Center and one of the largest such awards ever received at the University of Kansas.<\/p>\n\n\n\n

The DCOC will provide data coordination and biostatistics support, facilitate multisite study design and results dissemination, help coordinate with local health systems and train researchers and clinicians to increase their capacity to conduct pediatric research.<\/p>\n\n\n\n

The NIH created the IDeA States Pediatric Clinical Trials Network in 2016 to provide access to clinical trials for rural or underserved children living in IDeA states. These states have historically low levels of research funding and limited access to vital clinical trials. The program was created to broaden the geographic distribution of NIH funding for biomedical and behavioral research.<\/p>\n\n\n\n

There are 18 clinical research sites in the IDeA States Pediatric Clinical Trials Network. The grant will enable the Data Coordinating and Operations Center to serve as the centralized unit that will support clinical trials across it.<\/p>\n\n\n\n

Both UNMC and KU Medical Center have been part of the IDeA States Pediatric Clinical Trials Network since its inception.<\/p>\n\n\n\n

\u201cWe have maintained a close working relationship through the first two cycles (of the ECHO program),\u201d said Russell McCulloh, MD, associate vice chancellor for clinical research at UNMC and a principal investigator. \u201cThe big strength that Nebraska provides is the experience of our clinical research center and our experienced pediatric clinical trialists who have longstanding engagement in the network. These strengths are an excellent complement to KU\u2019s outstanding expertise in biostatistics and informatics, and both sides have strong track records in conducting multi-site clinical trials.\u201d<\/p>\n\n\n\n

UNMC will receive at least $5 million over the five-year course of the grant.<\/p>\n\n\n\n

\u201cKU Medical Center has been building the biostatistics and informatics infrastructure necessary for the DCOC for 20 years,\u201d said Matthew Mayo, PhD, founding chair of the KU Medical Center Department of Biostatistics and Data Science and the lead investigator on the grant. \u201cThe ultimate goal is to support high-quality, multi-center trials that generate valuable knowledge and lead to improved health outcomes for a wider range of children across the country.\u201d<\/p>\n\n\n\n

The clinical trials in the ECHO program focus on environmental influences that may affect child health, such as air pollution, family support, stress, sleep habits and diet. Recently published research has shown that adverse birth outcomes may be associated with arsenic in public drinking water, and that obesity, diabetes and high blood pressure before and after pregnancy are associated with higher blood pressure in children. These trials also provide access to health care teams for children that would not have had access otherwise.<\/p>\n\n\n\n

UNMC Interim Chancellor H. Dele Davies, MD, said it was exciting to partner with KU Medical Center on the new grant and advance such important work.<\/p>\n\n\n\n

\u201cKU Medical Center has extensive experience in biostatistics and informatics, making them uniquely positioned to achieve success,\u201d Dr. Davies said. \u201cWe are proud to partner with them, leveraging our strong experience in pediatric clinical trials alongside their expertise. Together, we will improve the lives and health of children in Nebraska, Kansas and far beyond.\u201d<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

A new grant will support efforts, provide coordination and increase capacity to conduct multisite pediatric 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