{"id":34335,"date":"2009-04-16T00:00:00","date_gmt":"2009-04-16T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2009\/04\/16\/dr-camras-inventor-of-most-effective-glaucoma-drug-dies\/"},"modified":"2022-09-02T20:36:47","modified_gmt":"2022-09-03T01:36:47","slug":"dr-camras-inventor-of-most-effective-glaucoma-drug-dies","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2009\/04\/16\/dr-camras-inventor-of-most-effective-glaucoma-drug-dies\/","title":{"rendered":"Dr. Camras, inventor of most effective glaucoma drug, dies"},"content":{"rendered":"


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\nCarl Camras, M.D.
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\n<\/TABLE>Carl Camras, M.D., the UNMC physician whose research led to the discovery of the most effective drug for treating glaucoma, died Tuesday at his home in Omaha after a long battle with heart failure. <\/p>\n

Dr. Camras, who was 55, served as chairman of the UNMC Department of Ophthalmology and Visual Sciences since 2000. He came to UNMC in 1991 as a tenured professor of ophthalmology. <\/p>\n

“Carl was a great physician and leader,” said UNMC Chancellor Harold M. Maurer, M.D. “His research on glaucoma benefited people around the globe. He had a ‘soft’ heart and was loved and respected by his patients and colleagues alike. We extend our deepest sympathy to his wife, Nancy, and to the entire family. His life was cut short, a loss to humanity.”<\/p>\n

A native of Chicago, Dr. Camras devoted more than 20 years of his career to looking for a better drug to treat glaucoma. His quest began as an undergraduate student at Yale University and continued in medical school at Columbia University College of Physicians and Surgery. At Columbia, he studied under Laszlo Bito, Ph.D., a legendary researcher-novelist from Hungary who worked at Columbia from 1966 to 1998.<\/p>\n

As a biochemistry major at Yale, Dr. Camras first conceived the idea that prostaglandins, a type of hormone found in virtually all tissues and organs, could lower the increased intraocular pressure that occurs with glaucoma. In 1996, using prostaglandins, Drs. Bito and Camras were the lead investigators in developing a new drug — latanoprost — for treatment of glaucoma. <\/p>\n


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\nServices for Dr. Camras
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\nA memorial service for Dr. Camras will be held at 1 p.m., Sunday, at Heafey-Heafey-Hoffmann-Dworak-Cutler Funeral Chapel, 7805 W. Center Road.<\/p>\n

In addition, a second memorial service for the UNMC community will be held at 4 p.m., Friday, in the Mary Ann “Maisie” Paustian Amphitheater, Room 3001 of the Michael F. Sorrell Center for Health Science Education.<\/p>\n

In lieu of flowers, the family requests that donations be made to the Camras Memorial Fund at the University of Nebraska Foundation. The Web site is being developed and gifts may be made online early next week at www.nufoundation.org<\/a>.
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\n<\/TABLE>The drug, sold under the trade name of Xalatan, was first marketed by Pharmacia. In short order, it became the most effective drug for the treatment of glaucoma. Since Xalatan was created, two additional glaucoma drugs using prostaglandins — Travatan and Lumigan — have reached the market place. With annual sales exceeding $2 billion, the three glaucoma drugs are by far the most lucrative ophthalmic pharmaceutical products in history. <\/p>\n

Glaucoma is a disease caused by increased intraocular pressure (IOP) resulting either from a malformation or malfunction of the eye’s drainage structures. Left untreated, an elevated IOP causes irreversible damage to the optic nerve and retinal fibers resulting in a progressive, permanent loss of vision. Early detection and treatment can slow or even halt progression of the disease. <\/p>\n

Glaucoma is a leading cause of blindness affecting more than 2 million people in the United States. It’s estimated that another million people have glaucoma but have not been diagnosed.<\/p>\n

“Carl Camras was a genius and one of the leading glaucoma specialists in the world,” said Tom Hejkal, M.D., professor of ophthalmology at UNMC. “I would have said the leading glaucoma specialist in the world, but I know Carl’s modesty would have prompted him to refuse such high praise.<\/p>\n

“Not only did Carl know all of the scientific literature in his field, but he knew most of the authors personally, where they went to school, their hobbies and the names of their spouses and children. Carl was also one of the kindest and most generous men I have had the privilege to know.” <\/p>\n

Dr. Camras’ incredible research portfolio includes more than 280 published articles in scientific journals. His impact on glaucoma patients could possibly continue even after his death, as he has a patent on a glaucoma shunt, which could help patients in years to come. He has been an invited speaker at literally hundreds of national and international conferences. <\/p>\n

After completing medical school, Dr. Camras did his internship and residency training at the University of California at Los Angeles (UCLA) School of Medicine. He then completed a fellowship in glaucoma at Mount Sinai School of Medicine in New York City. He remained on the faculty at Mount Sinai from 1983 to 1991, when he accepted the position at UNMC.<\/p>\n

Being an inventor came naturally to Dr. Camras. His late father, Marvin Camras, owned some 550 patents. An engineer in Chicago, Marvin’s research focused on preserving sound rather than sight. He invented magnetic recording, which was a forerunner to modern tape recording. The magnetic coatings he developed were used on VCR tapes and computer disks.<\/p>\n

A recurring theme for all who knew Dr. Camras was the outstanding character of the man.<\/p>\n

“One of Carl’s greatest qualities was the way he treated all people with respect,” Dr. Hejkal said. “He treated even young students just starting out in his laboratory as colleagues and showed them as much consideration and respect as he showed the chairman of an ophthalmology department or the dean of a medical school.”<\/p>\n

Survivors include: his mother, Isabelle Camras, Chicago; his brothers, Robert and Louis, both of Chicago, and Michael, San Francisco; a sister and brother-in-law, Ruth and Charlie Pikler, Chicago; his wife, Nancy; and two daughters, Lucinda and Melanie. <\/p>\n

Continuing the family tradition of seeking new inventions, Lucinda, a graduate student in biomedical engineering at Duke University, has been working with her father on glaucoma drainage devices. Last May, father and daughter presented on the devices at a major glaucoma symposium hosted by UNMC. <\/p>\n

The leading glaucoma experts in the world came to Omaha and made presentations at the symposium — most out of respect for Dr. Camras and his outstanding contributions to the field. <\/p>\n

What others are saying<\/B> <\/p>\n

“He was one of the chairmen I hired when I was dean of the College of Medicine, and I will always be proud of that. Carl was a wonderful person, an internationally famous ophthalmologist and a great leader. I value his friendship. He was as kind and generous a person as you will ever meet. He lived life to the fullest having conquered a potentially fatal disease (Hodgkin’s disease) as a young man. He never allowed illness or not feeling the best to be a reason for not excelling.” James Armitage, M.D., professor, internal medicine, section of oncology-hematology <\/I><\/B><\/p>\n

“Dr. Camras endured a long battle with heart failure from restrictive pericarditis, which was a complication of the radiation therapy he received for treatment of Hodgkin’s disease more than 25 years ago. Through his extensive review of the literature on this subject over the last two years, I believe he knew more about this condition than most of the experts in the field. I am confident that, given a little more time in good health, he would have discovered a cure.” Tom Hejkal, M.D., professor and vice chairman of clinical care, ophthalmology and visual sciences<\/I><\/B><\/p>\n

“Carl was an internationally recognized and respected glaucoma specialist. He elevated the UNMC Department of Ophthalmology to national prominence both clinically and through research. It was my good fortune to be associated with Carl throughout his UNMC career. He was a friend. His legacy of well trained ophthalmologists, his participation in the development of latanoprost (Xalatan) a treatment for glaucoma used worldwide as an initial treatment of choice, and his research contributions all added to the growing reputation of UNMC. Carl was a physician who cared deeply about his patients.” Stanley M. Truhlsen, M.D., emeritus professor and chairman, ophthalmology and visual sciences, and longtime donor to UNMC who created the Truhlsen Eye Research Laboratories in the Durham Research Center<\/I><\/B><\/p>\n

“Carl Camras is undoubtedly one of the most extraordinary individuals I have known. Despite his lingering illness he continued to perform his leadership responsibilities, to care for his numerous patients and to place his needs behind those of others. Amongst an array of talents, Carl had a photographic memory, and he was always the first to ask after your family or to remember an alumnus or colleague. Carl lived life to the fullest. I will truly miss him and his friendship.” John Gollan, M.D., Ph.D., dean, UNMC College of Medicine <\/I><\/B><\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

Carl Camras, M.D., the UNMC physician whose research led to the discovery of the most effective drug for treating glaucoma, died Tuesday at his home in Omaha after a long battle with heart failure. 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