{"id":41041,"date":"2012-09-01T00:00:00","date_gmt":"2012-09-01T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2012\/09\/01\/research-highlights-unmc-researchers-procure-major-nih-grants\/"},"modified":"2012-09-01T00:00:00","modified_gmt":"2012-09-01T05:00:00","slug":"research-highlights-unmc-researchers-procure-major-nih-grants","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2012\/09\/01\/research-highlights-unmc-researchers-procure-major-nih-grants\/","title":{"rendered":"Research Highlights &#8211; UNMC researchers procure major NIH grants"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p><strong>Nora Sarvetnick,  Ph.D.,<\/strong> surgery-transplantation, has been awarded a $2.6 million National  Institutes of Health grant by the National Institutes of Allergy and Infectious  Diseases (NIAID).\u00a0 She will study the role of a subset of immune cells &#8211;  CD8 T cells expressed in the interleukin 18 receptor &#8211; in precipitating the  onset of autoimmune diabetes.\u00a0The role of these cells will provide a new  model for understanding how diabetes develops in humans and open avenues for  the prevention and treatment of type 1 diabetes.\u00a0 <a href=\"http:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=8374068&#038;icde=13611984&#038;ddparam=&#038;ddvalue=&#038;ddsub=&#038;cr=1&#038;csb=default&#038;cs=ASC\" target=\"_blank\" rel=\"noopener\">For more information,  click here.<\/a><br \/>\n  <a href=\"http:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=8374068&#038;icde=13611984&#038;ddparam=&#038;ddvalue=&#038;ddsub=&#038;cr=1&#038;csb=default&#038;cs=ASC\"><\/a><\/p>\n<p><strong>Huangui Xiong, M.D.,  Ph.D.,<\/strong> pharmacology\/experimental neuroscience, has been awarded a $1.8  million National Institutes of Health grant by the National Institutes of  Neurological Disorders and Stroke (NINDS) to study how HIV-1 triggers microglia  activation, a phagocytic cell strongly linked to HIV-1 activated neurocognitive  disorders (HAND).\u00a0 Dr. Xiong will explore the ion-channel, Kv1.3 as a  potential target for the development of therapeutic strategies in HAND. <a href=\"http:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=8329859&#038;icde=13612057&#038;ddparam=&#038;ddvalue=&#038;ddsub=&#038;cr=1&#038;csb=default&#038;cs=ASC\" target=\"_blank\" rel=\"noopener\">For  more information, click here.<\/a><br \/>\n  <a href=\"http:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=8329859&#038;icde=13612057&#038;ddparam=&#038;ddvalue=&#038;ddsub=&#038;cr=1&#038;csb=default&#038;cs=ASC\"><\/a><\/p>\n<p><strong>Surinder Batra, Ph.D.,<\/strong> biochemistry and molecular biology, has been awarded a $147,000 National  Institutes of Health grant by the National Cancer Institute (NCI) to further his  work in the role of MUC4 in pancreatic cancer.\u00a0 He aims to investigate  whether down regulating the expression of MUC4 can be used in combination with  other chemotherapeutic drugs to treat pancreatic cancer. <a href=\"http:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=8386424&#038;icde=13611881&#038;ddparam=&#038;ddvalue=&#038;ddsub=&#038;cr=1&#038;csb=default&#038;cs=ASC\" target=\"_blank\" rel=\"noopener\">For more information,  click here.<\/a><\/p>\n<p><strong>Paul Sorgen, Ph.D.,<\/strong> biochemistry and molecular biology, was the recipient of a University of  Nebraska Foundation equipment grant.\u00a0 He will use the grant to purchase an  EmulsiFlex-C3 Homogenizer to be used in the rupture of cellular  membranes.\u00a0This equipment will be available to campus researchers who need  a more gentle method of cellular disruption to further their structural biology and  biophysics studies. <\/p>\n<p>The School of Allied Health Professions has received two  grants aimed at improving health care in rural communities. The largest grant &#8211;  from the Health Resources and Services  Administration &#8211; provides $993,910 over  five years and will allow UNMC to host a biennial Physician  Assistants Rural Primary Care National Conference in 2014 and 2016. <strong>Michael Huckabee, Ph.D.,<\/strong> and <strong>Kyle Meyer, Ph.D.,<\/strong> are co-primary  investigators. The second grant &#8211; from the Agency for Healthcare Research and  Quality &#8211; provides $593,088 to improve patient care and safety by reducing  inpatient falls in critical access hospitals that primarily serve rural older  adult populations. Katherine Jones, Ph.D. is the primary investigator. \u00a0<\/p>\n<p>The <strong>UNMC  Department of Ophthalmology and Visual Sciences<\/strong> has received a $110,000  grant<strong> <\/strong>from Research to Prevent  Blindness to conduct research to discover causes of and cures for eye  diseases such as macular degeneration and glaucoma. RPB is the world&#8217;s leading  voluntary organization in support of eye research.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Will study diabetes, neurocognitive disorders, pancreatic cancer.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-41041","post","type-post","status-publish","format-standard","hentry","category-uncategorized","department-intercom"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research Highlights - UNMC researchers procure major NIH grants<\/title>\n<meta name=\"description\" content=\"Will study diabetes, neurocognitive disorders, pancreatic cancer.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.unmc.edu\/newsroom\/2012\/09\/01\/research-highlights-unmc-researchers-procure-major-nih-grants\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research Highlights - UNMC researchers procure major NIH grants\" \/>\n<meta property=\"og:description\" content=\"Will study diabetes, neurocognitive disorders, pancreatic cancer.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.unmc.edu\/newsroom\/2012\/09\/01\/research-highlights-unmc-researchers-procure-major-nih-grants\/\" \/>\n<meta property=\"og:site_name\" content=\"Newsroom\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/unmcedu\" \/>\n<meta property=\"article:published_time\" content=\"2012-09-01T05:00:00+00:00\" \/>\n<meta name=\"author\" content=\"Ryan Shaw\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@unmc\" \/>\n<meta name=\"twitter:site\" content=\"@unmc\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ryan Shaw\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2012\/09\/01\/research-highlights-unmc-researchers-procure-major-nih-grants\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2012\/09\/01\/research-highlights-unmc-researchers-procure-major-nih-grants\/\"},\"author\":{\"name\":\"Ryan Shaw\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/person\/f532918153ff234280992910aad23556\"},\"headline\":\"Research Highlights &#8211; 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