{"id":44314,"date":"2013-09-05T00:00:00","date_gmt":"2013-09-05T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2013\/09\/05\/research-funding-during-past-month-exceeds-2-8-million\/"},"modified":"2022-08-29T14:37:54","modified_gmt":"2022-08-29T19:37:54","slug":"research-funding-during-past-month-exceeds-2-8-million","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2013\/09\/05\/research-funding-during-past-month-exceeds-2-8-million\/","title":{"rendered":"Research funding during past month exceeds $2.8 million"},"content":{"rendered":"

\nGrants will study HIV, gout, cell signaling<\/em><\/strong><\/p>\n

\nTwenty-six new research awards representing more than $2.8 million in new funding were received by College of Medicine faculty during the past month. They included:<\/p>\n

\nHoward Fox, M.D., Ph.D.,<\/strong> pharmacology and experimental neuroscience, has received a National Institutes of Health U24 grant<\/a> from the National Institutes of Mental Health (NIMH). This $883,000 award designates Dr. Fox and UNMC as the data coordinating center to the National NeuroAIDS Tissue Consortium (NNTC), a resource for investigators conducting NeuroAIDS research to identify the neuropathogenic mechanisms involved in HIV disease of the central and peripheral nervous systems. Investigators using this resource examine emerging research topics in the NeuroAIDS field such as: (a) eradication of HIV from persistent CNS reservoirs; (b) pathogenic mechanisms of HIV-associated neurocognitive disorders (HAND) in setting of long-term Highly Active Antiretroviral Therapy (HAART); and (c) HIV and aging.<\/p>\n

\nNora Sarvetnick, Ph.D.,<\/strong> director of the Mary and Dick Holland Regenerative Medicine Program and professor, surgery-transplant, will be the UNMC lead for a $260,000 collaborative research project translating cellular markers of diabetes from existing immunophenotyping techniques to new mass cytometry technologies. Mass cytometry combines the single cellular imaging power of flow cytometry with the proteomics strategies of mass spectrometry increasing the amount of information that can be determined from very small samples. Dr. Sarvetnick will apply this technology to the discovery of novel immunological markers in pediatric diabetes patients.<\/p>\n

\nPaul Sorgen, Ph.D., <\/strong>biochemistry and molecular biology, is the UNMC lead for a National Institutes of Health, National Institute of General Medical Sciences (NIGM) funded project<\/a> initiated through the University of Medicine and Dentistry of New Jersey. This $135,000 project will explore the mechanisms by which intercellular molecular signaling throughout the body is modulated. Defects in cellular signaling are responsible for a number of human pathologies. Understanding these mechanisms will contribute to the design of interventions for these defects.<\/p>\n

\nTed Mikuls, M.D.,<\/strong> internal medicine-rheumatology, is the UNMC lead for a National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) program project grant<\/a>. This $120,000 award will compare the effectiveness of a novel pharmacy-based “virtual” Gout Clinic that includes protocol-driven care to usual care in the treatment of chronic gout. This study hopes to address the current gaps in the quality of care for gout patients by furthering the understanding of the genetic and environmental influences on gout and hyperuricemia in different races and ethnicities.<\/p>\n

\nAngela Hewlett, M.D.,<\/strong> internal medicine-infectious diseases, is the recipient of a National Strategic Research Institute (NSRI) award. Dr. Hewlett will be developing surveillance assays for the diagnosis of microbial contamination.<\/p>\n

\nThe American Heart Association awards pre- and post-doctoral fellowships to help trainees initiate careers in cardiovascular and stroke research while obtaining significant research results under the supervision of a mentor. The following investigators have received American Heart Association (Midwest Affiliate) fellowship awards:<\/p>\n