{"id":44315,"date":"2013-09-05T00:00:00","date_gmt":"2013-09-05T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2013\/09\/05\/industry-sponsored-contracts-2\/"},"modified":"2013-09-05T00:00:00","modified_gmt":"2013-09-05T05:00:00","slug":"industry-sponsored-contracts-2","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2013\/09\/05\/industry-sponsored-contracts-2\/","title":{"rendered":"Industry-sponsored contracts"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>\nThe following industry-sponsored contracts have been received. Here is more <a href=\"http:\/\/net.unmc.edu\/ctsearch\/index_unmc.php\">information<\/a> on clinical trials enrolling patients at UNMC.<\/p>\n<p>\n<strong>James Gigantelli, M.D.,<\/strong> ophthalmology and visual sciences, is the UNMC lead for a multi-center Phase III clinical trial to evaluate the safety and effectiveness of a novel protein therapy for the treatment of thyroid eye disease (TED).<\/p>\n<p>\n<strong>Jue Wang, M.D.,<\/strong> internal medicine &ndash; oncology\/hematology, is the UNMC lead for a multi-center Phase I\/II clinical trial to evaluate the safety and effectiveness of a small molecule inhibitor of a heat shock protein believed to support the growth and spread of many cancer cells. Patients with non-responsive prostate cancer will either receive the inhibitor in combination with existing chemotherapeutics or alone and evaluated for a reduction in tumor cell growth.<\/p>\n<p>\n<strong>Pamela Carmines, Ph.D.,<\/strong> cellular and integrative physiology, is evaluating the impact of ROMK (renal outer medullary K+ channels) on renal arteriole function. K+ channels may play a role in the changes in renal function found early in diabetes which lead to diabetic nephropathy and the eventual decline in renal function in diabetic patients.<\/p>\n<p>\n<strong>Austin Thompson, M.D., <\/strong>internal medicine &ndash; pulmonary, is the UNMC lead for two multi-center clinical trials to evaluate the effectiveness of a new oral prostacyclin-like compound on the long-term outcome of patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension.<\/p>\n<p>\n<strong>Elizabeth Reed, M.D.,<\/strong> internal medicine &ndash; oncology\/hematology, is the UNMC lead for a multi-center Phase II clinical trial to evaluate the safety and effectiveness of adding an additional chemotherapeutic agent to current treatment for patients with HER2- breast cancer.<\/p>\n<p>\n<strong>William Burke, M.D.,<\/strong> psychiatry, is the UNMC lead for a multi-center Phase II clinical trial to evaluate an orally administered therapeutic agent for the treatment of Alzheimer&rsquo;s disease on the safety and effectiveness in treating the symptoms of agitation and aggression in Alzheimer&rsquo;s patients.<\/p>\n<p>\n<strong>Julia Bridge, M.D., <\/strong>pathology and microbiology, is investigating the clinical specificity of a new molecular assay for the detection of bladder cancer.<\/p>\n<p>\n<strong>Quan Dong Nguyen, M.D.,<\/strong> ophthalmology and visual sciences, is the UNMC lead on a Phase I\/II clinical trial to determine the safety and tolerability of a currently marketed anti-inflammatory agent for a new use in the treatment of patients with non-infectious uveitis.<\/p>\n<p>\n<strong>Andre Kalil, M.D.,<\/strong> internal medicine &ndash; infectious diseases, is the UNMC lead on a Phase III Clinical Trial to assess the safety and effectiveness of a recombinant human soluble thrombomodulin when used to treat complications of sepsis.<\/p>\n<p>\n<strong>Debra Reilly, M.D., <\/strong>surgery &ndash; plastic &amp; reconstructive surgery, is the UNMC collaborator for a study on injuries related to glass-fronted fireplaces.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The following industry-sponsored contracts have been received. Here is more information on clinical trials enrolling patients at UNMC. James Gigantelli, M.D., ophthalmology and visual sciences, is the UNMC lead for a multi-center Phase III clinical trial to evaluate the safety and effectiveness of a novel protein therapy for the treatment of thyroid eye disease (TED). [&hellip;]<\/p>\n","protected":false},"author":112,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-44315","post","type-post","status-publish","format-standard","hentry","category-uncategorized","department-intercom"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Industry-sponsored contracts<\/title>\n<meta name=\"description\" content=\"The following industry-sponsored contracts have been received. Here is more information on clinical trials enrolling patients at UNMC. James Gigantelli,\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.unmc.edu\/newsroom\/2013\/09\/05\/industry-sponsored-contracts-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Industry-sponsored contracts\" \/>\n<meta property=\"og:description\" content=\"The following industry-sponsored contracts have been received. Here is more information on clinical trials enrolling patients at UNMC. 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