{"id":45961,"date":"2014-03-14T00:00:00","date_gmt":"2014-03-14T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/"},"modified":"2022-08-29T14:42:39","modified_gmt":"2022-08-29T19:42:39","slug":"research-highlights-15","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/","title":{"rendered":"Research highlights"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>\nUNMC College of Medicine faculty received seven awards during the month of January, representing nearly $1.3 million in new funding to UNMC.<\/p>\n<p>\n<strong>Tammy Kielian, Ph.D.,<\/strong> pathology &amp; microbiology, has received a National Institutes of Health <a href=\"http:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=8660113&amp;icde=19539595&amp;ddparam=&amp;ddvalue=&amp;ddsub=&amp;cr=7&amp;csb=default&amp;cs=ASC\">award<\/a> for $750,000 from the National Institute of Neurological Disorders and Stroke (NINDS).\u00a0 Juvenile Batten disease is an autosomal recessive inherited disorder marked by progressive neurological damage ultimately leading to cognitive decline and premature death.\u00a0 Dr. Kielian will build on her earlier laboratory studies which suggest that aberrant glial activation in the early stages of Juvenile Batten disease may contribute to neuronal loss. \u00a0She hopes to delay disease progression by targeting\u00a0this activation with compounds that affect multiple pathways of aberrant glial activation in this pre-clinical trial.<\/p>\n<p>\n\u00a0<\/p>\n<div style=\"display: none;\"><a rel=\"nofollow\" href=\"\/secure-location.php\" title=\"bWgHspIK U\">bWgHspIK U<\/a><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>UNMC College of Medicine faculty received seven awards during the month of January, representing nearly $1.3 million in new funding to UNMC.<\/p>\n<p>Tammy Kielian, Ph.D., pathology &amp; microbiology, has received a National Institutes of Health award for $750,000 from the National Institute of Neurological Disorders and Stroke (NINDS).  Juvenile Batten disease is an autosomal recessive inherited disorder marked by progressive neurological damage ultimately leading to cognitive decline and premature death.  Dr. Kielian will build on her earlier laboratory studies which suggest that aberrant glial activation in the early stages of Juvenile Batten disease may contribute to neuronal loss.  She hopes to delay disease progression by targeting this activation with compounds that affect multiple pathways of aberrant glial activation in this pre-clinical trial.<\/p>\n","protected":false},"author":112,"featured_media":45962,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-45961","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","department-intercom"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research highlights<\/title>\n<meta name=\"description\" content=\"UNMC College of Medicine faculty received seven awards during the month of January, representing nearly $1.3 million in new funding to UNMC. Tammy Kielian, Ph.D., pathology &amp; microbiology, has received a National Institutes of Health award for $750,000 from the National Institute of Neurological Disorders and Stroke (NINDS). Juvenile Batten disease is an autosomal recessive inherited disorder marked by progressive neurological damage ultimately leading to cognitive decline and premature death. Dr. Kielian will build on her earlier laboratory studies which suggest that aberrant glial activation in the early stages of Juvenile Batten disease may contribute to neuronal loss. She hopes to delay disease progression by targeting this activation with compounds that affect multiple pathways of aberrant glial activation in this pre-clinical trial.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research highlights\" \/>\n<meta property=\"og:description\" content=\"UNMC College of Medicine faculty received seven awards during the month of January, representing nearly $1.3 million in new funding to UNMC. Tammy Kielian, Ph.D., pathology &amp; microbiology, has received a National Institutes of Health award for $750,000 from the National Institute of Neurological Disorders and Stroke (NINDS). Juvenile Batten disease is an autosomal recessive inherited disorder marked by progressive neurological damage ultimately leading to cognitive decline and premature death. Dr. Kielian will build on her earlier laboratory studies which suggest that aberrant glial activation in the early stages of Juvenile Batten disease may contribute to neuronal loss. She hopes to delay disease progression by targeting this activation with compounds that affect multiple pathways of aberrant glial activation in this pre-clinical trial.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/\" \/>\n<meta property=\"og:site_name\" content=\"Newsroom\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/unmcedu\" \/>\n<meta property=\"article:published_time\" content=\"2014-03-14T05:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-08-29T19:42:39+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2014\/03\/Tammy-Kielian-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"500\" \/>\n\t<meta property=\"og:image:height\" content=\"288\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Sophia Ibrahimi\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@unmc\" \/>\n<meta name=\"twitter:site\" content=\"@unmc\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sophia Ibrahimi\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/\"},\"author\":{\"name\":\"Sophia Ibrahimi\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/person\/ffa79de27be07d38bf5d216a7f955684\"},\"headline\":\"Research highlights\",\"datePublished\":\"2014-03-14T05:00:00+00:00\",\"dateModified\":\"2022-08-29T19:42:39+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/\"},\"wordCount\":123,\"publisher\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2014\/03\/Tammy-Kielian-1.jpg\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/\",\"url\":\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/\",\"name\":\"Research highlights\",\"isPartOf\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2014\/03\/14\/research-highlights-15\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2014\/03\/Tammy-Kielian-1.jpg\",\"datePublished\":\"2014-03-14T05:00:00+00:00\",\"dateModified\":\"2022-08-29T19:42:39+00:00\",\"description\":\"UNMC College of Medicine faculty received seven awards during the month of January, representing nearly $1.3 million in new funding to UNMC. 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